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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPEB2
Full Name:
Cytoplasmic polyadenylation element-binding protein 2
Alias:
CPE-binding protein 2; CPE-BP2; cytoplasmic polyadenylation element binding protein 2; hCPEB-2
Type:
Mass (Da):
64926
Number AA:
589
UniProt ID:
Q7Z5Q1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0006417
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
P
P
P
S
P
D
S
E
N
G
F
Site 2
S8
M
P
P
P
S
P
D
S
E
N
G
F
Y
P
G
Site 3
Y13
P
D
S
E
N
G
F
Y
P
G
L
P
S
S
M
Site 4
S27
M
N
P
A
F
F
P
S
F
S
P
V
S
P
H
Site 5
S40
P
H
G
C
T
G
L
S
V
P
T
S
G
G
G
Site 6
S86
A
A
P
Q
Q
P
Q
S
R
R
S
P
V
S
P
Site 7
S89
Q
Q
P
Q
S
R
R
S
P
V
S
P
Q
L
Q
Site 8
S92
Q
S
R
R
S
P
V
S
P
Q
L
Q
Q
Q
H
Site 9
Y113
F
L
Q
Q
R
N
S
Y
N
H
H
Q
P
L
L
Site 10
S123
H
Q
P
L
L
K
Q
S
P
W
S
N
H
Q
S
Site 11
S126
L
L
K
Q
S
P
W
S
N
H
Q
S
S
G
W
Site 12
S130
S
P
W
S
N
H
Q
S
S
G
W
G
T
G
S
Site 13
T135
H
Q
S
S
G
W
G
T
G
S
M
S
W
G
A
Site 14
T151
H
G
R
D
H
R
R
T
G
N
M
G
I
P
G
Site 15
T159
G
N
M
G
I
P
G
T
M
N
Q
I
S
P
L
Site 16
S164
P
G
T
M
N
Q
I
S
P
L
K
K
P
F
S
Site 17
S171
S
P
L
K
K
P
F
S
G
N
V
I
A
P
P
Site 18
S183
A
P
P
K
F
T
R
S
T
P
S
L
T
P
K
Site 19
T184
P
P
K
F
T
R
S
T
P
S
L
T
P
K
S
Site 20
S186
K
F
T
R
S
T
P
S
L
T
P
K
S
W
I
Site 21
T188
T
R
S
T
P
S
L
T
P
K
S
W
I
E
D
Site 22
S191
T
P
S
L
T
P
K
S
W
I
E
D
N
V
F
Site 23
T200
I
E
D
N
V
F
R
T
D
N
N
S
N
T
L
Site 24
S204
V
F
R
T
D
N
N
S
N
T
L
L
P
L
Q
Site 25
T206
R
T
D
N
N
S
N
T
L
L
P
L
Q
V
R
Site 26
S223
L
Q
L
P
A
W
G
S
D
S
L
Q
D
S
W
Site 27
S225
L
P
A
W
G
S
D
S
L
Q
D
S
W
C
T
Site 28
S229
G
S
D
S
L
Q
D
S
W
C
T
A
A
G
T
Site 29
S244
S
R
I
D
Q
D
R
S
R
M
Y
D
S
L
N
Site 30
Y247
D
Q
D
R
S
R
M
Y
D
S
L
N
M
H
S
Site 31
S249
D
R
S
R
M
Y
D
S
L
N
M
H
S
L
E
Site 32
S254
Y
D
S
L
N
M
H
S
L
E
N
S
L
I
D
Site 33
S258
N
M
H
S
L
E
N
S
L
I
D
I
M
R
A
Site 34
S275
D
P
L
K
G
R
L
S
Y
P
H
P
G
T
D
Site 35
Y276
P
L
K
G
R
L
S
Y
P
H
P
G
T
D
N
Site 36
T281
L
S
Y
P
H
P
G
T
D
N
L
L
M
L
N
Site 37
S292
L
M
L
N
G
R
S
S
L
F
P
I
D
D
G
Site 38
S306
G
L
L
D
D
G
H
S
D
Q
V
G
V
L
N
Site 39
S314
D
Q
V
G
V
L
N
S
P
T
C
Y
S
A
H
Site 40
Y318
V
L
N
S
P
T
C
Y
S
A
H
Q
N
G
E
Site 41
S331
G
E
R
I
E
R
F
S
R
K
V
F
V
G
G
Site 42
T349
D
I
D
E
D
E
I
T
A
S
F
R
R
F
G
Site 43
S351
D
E
D
E
I
T
A
S
F
R
R
F
G
P
L
Site 44
S368
D
W
P
H
K
A
E
S
K
S
Y
F
P
P
K
Site 45
S370
P
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
Site 46
Y371
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
A
Site 47
Y403
I
E
E
D
G
K
L
Y
L
C
V
S
S
P
T
Site 48
S407
G
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
Site 49
S408
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
P
Site 50
S424
Q
I
R
P
W
N
L
S
D
S
D
F
V
M
D
Site 51
S426
R
P
W
N
L
S
D
S
D
F
V
M
D
G
S
Site 52
S433
S
D
F
V
M
D
G
S
Q
P
L
D
P
R
K
Site 53
T441
Q
P
L
D
P
R
K
T
I
F
V
G
G
V
P
Site 54
Y464
A
M
I
M
D
R
L
Y
G
G
V
C
Y
A
G
Site 55
Y469
R
L
Y
G
G
V
C
Y
A
G
I
D
T
D
P
Site 56
T474
V
C
Y
A
G
I
D
T
D
P
E
L
K
Y
P
Site 57
Y480
D
T
D
P
E
L
K
Y
P
K
G
A
G
R
V
Site 58
S490
G
A
G
R
V
A
F
S
N
Q
Q
S
Y
I
A
Site 59
Y495
A
F
S
N
Q
Q
S
Y
I
A
A
I
S
A
R
Site 60
Y520
K
R
V
E
V
K
P
Y
V
L
D
D
Q
M
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation