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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
APBB1IP
Full Name:
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Alias:
AB1IP; Amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; INAG1; PREL1; Proline-rich EVH1 ligand 1; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; RARP1; RIAM
Type:
Binding protein; Plasma membrane, cytoplasm, cell projection, cell junction, cytoskeleton protein
Mass (Da):
73183
Number AA:
666
UniProt ID:
Q7Z5R6
International Prot ID:
IPI00376219
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005829
GO:0019898
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
T
Q
S
L
G
V
D
T
L
P
P
P
D
P
N
Site 2
Y45
P
P
R
A
E
F
N
Y
S
V
G
F
K
D
L
Site 3
S46
P
R
A
E
F
N
Y
S
V
G
F
K
D
L
N
Site 4
S55
G
F
K
D
L
N
E
S
L
N
A
L
E
D
Q
Site 5
S76
A
D
L
V
A
D
I
S
E
A
E
Q
R
T
I
Site 6
S89
T
I
Q
A
Q
K
E
S
L
Q
N
Q
H
H
S
Site 7
S96
S
L
Q
N
Q
H
H
S
A
S
L
Q
A
S
I
Site 8
S98
Q
N
Q
H
H
S
A
S
L
Q
A
S
I
F
S
Site 9
Y124
A
A
T
G
I
S
Q
Y
E
D
D
L
P
P
P
Site 10
S150
P
P
P
P
E
P
L
S
Q
E
E
E
E
A
Q
Site 11
S191
M
N
D
N
S
T
K
S
L
M
V
D
E
R
Q
Site 12
Y225
D
W
C
L
Y
E
I
Y
P
E
L
Q
I
E
R
Site 13
S245
E
N
V
V
E
V
L
S
D
W
T
R
D
T
E
Site 14
T251
L
S
D
W
T
R
D
T
E
N
K
I
L
F
L
Site 15
Y264
F
L
E
K
E
E
K
Y
A
V
F
K
N
P
Q
Site 16
Y274
F
K
N
P
Q
N
F
Y
L
D
N
R
G
K
K
Site 17
S283
D
N
R
G
K
K
E
S
K
E
T
N
E
K
M
Site 18
T286
G
K
K
E
S
K
E
T
N
E
K
M
N
A
K
Site 19
S297
M
N
A
K
N
K
E
S
L
L
E
E
S
F
C
Site 20
Y318
P
E
L
E
G
A
L
Y
L
K
E
D
G
K
K
Site 21
S326
L
K
E
D
G
K
K
S
W
K
R
R
Y
F
L
Site 22
Y331
K
K
S
W
K
R
R
Y
F
L
L
R
A
S
G
Site 23
S337
R
Y
F
L
L
R
A
S
G
I
Y
Y
V
P
K
Site 24
Y340
L
L
R
A
S
G
I
Y
Y
V
P
K
G
K
T
Site 25
Y341
L
R
A
S
G
I
Y
Y
V
P
K
G
K
T
K
Site 26
T349
V
P
K
G
K
T
K
T
S
R
D
L
A
C
F
Site 27
Y365
Q
F
E
N
V
N
I
Y
Y
G
T
Q
H
K
M
Site 28
Y374
G
T
Q
H
K
M
K
Y
K
A
P
T
D
Y
C
Site 29
Y380
K
Y
K
A
P
T
D
Y
C
F
V
L
K
H
P
Site 30
Y398
K
E
S
Q
Y
I
K
Y
L
C
C
D
D
T
R
Site 31
T406
L
C
C
D
D
T
R
T
L
N
Q
W
V
M
G
Site 32
Y419
M
G
I
R
I
A
K
Y
G
K
T
L
Y
D
N
Site 33
T422
R
I
A
K
Y
G
K
T
L
Y
D
N
Y
Q
R
Site 34
Y424
A
K
Y
G
K
T
L
Y
D
N
Y
Q
R
A
V
Site 35
Y427
G
K
T
L
Y
D
N
Y
Q
R
A
V
A
K
A
Site 36
S455
A
A
A
P
A
Q
P
S
T
G
P
K
T
G
T
Site 37
T456
A
A
P
A
Q
P
S
T
G
P
K
T
G
T
T
Site 38
T460
Q
P
S
T
G
P
K
T
G
T
T
Q
P
N
G
Site 39
T462
S
T
G
P
K
T
G
T
T
Q
P
N
G
Q
I
Site 40
S475
Q
I
P
Q
A
T
H
S
V
S
A
V
L
Q
E
Site 41
S477
P
Q
A
T
H
S
V
S
A
V
L
Q
E
A
Q
Site 42
S490
A
Q
R
H
A
E
T
S
K
D
K
K
P
A
L
Site 43
S514
R
A
P
H
A
P
K
S
S
L
P
P
P
P
P
Site 44
S515
A
P
H
A
P
K
S
S
L
P
P
P
P
P
V
Site 45
S525
P
P
P
P
V
R
R
S
S
D
T
S
G
S
P
Site 46
S526
P
P
P
V
R
R
S
S
D
T
S
G
S
P
A
Site 47
T528
P
V
R
R
S
S
D
T
S
G
S
P
A
T
P
Site 48
S529
V
R
R
S
S
D
T
S
G
S
P
A
T
P
L
Site 49
S531
R
S
S
D
T
S
G
S
P
A
T
P
L
K
A
Site 50
T534
D
T
S
G
S
P
A
T
P
L
K
A
K
G
T
Site 51
Y590
V
P
P
P
P
P
S
Y
A
G
I
A
G
S
E
Site 52
S596
S
Y
A
G
I
A
G
S
E
L
P
P
P
P
P
Site 53
S616
A
P
A
P
V
P
D
S
A
R
P
P
P
A
V
Site 54
S652
G
G
E
Q
D
F
M
S
D
L
M
K
A
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation