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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR53
Full Name:
WD repeat-containing protein 53
Alias:
Type:
Mass (Da):
38989
Number AA:
358
UniProt ID:
Q7Z5U6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
W
T
G
G
H
S
S
P
V
L
C
L
N
A
Site 2
S26
S
K
E
G
L
L
A
S
G
A
E
G
G
D
L
Site 3
T34
G
A
E
G
G
D
L
T
A
W
G
E
D
G
T
Site 4
T41
T
A
W
G
E
D
G
T
P
L
G
H
T
R
F
Site 5
Y68
P
S
C
P
T
K
L
Y
A
S
H
G
E
T
I
Site 6
S82
I
S
V
L
D
V
R
S
L
K
D
S
L
D
H
Site 7
S86
D
V
R
S
L
K
D
S
L
D
H
F
H
V
N
Site 8
S101
E
E
E
I
N
C
L
S
L
N
Q
T
E
N
L
Site 9
T105
N
C
L
S
L
N
Q
T
E
N
L
L
A
S
A
Site 10
S111
Q
T
E
N
L
L
A
S
A
D
D
S
G
A
I
Site 11
S131
E
N
K
K
V
I
R
S
L
K
R
H
S
N
I
Site 12
S136
I
R
S
L
K
R
H
S
N
I
C
S
S
V
A
Site 13
S140
K
R
H
S
N
I
C
S
S
V
A
F
R
P
Q
Site 14
S141
R
H
S
N
I
C
S
S
V
A
F
R
P
Q
R
Site 15
S151
F
R
P
Q
R
P
Q
S
L
V
S
C
G
L
D
Site 16
S165
D
M
Q
V
M
L
W
S
L
Q
K
A
R
P
L
Site 17
T175
K
A
R
P
L
W
I
T
N
L
Q
E
D
E
T
Site 18
T182
T
N
L
Q
E
D
E
T
E
E
M
E
G
P
Q
Site 19
S190
E
E
M
E
G
P
Q
S
P
G
Q
L
L
N
P
Site 20
S213
A
S
C
G
N
I
F
S
C
G
A
E
D
G
K
Site 21
S245
K
G
H
T
S
G
V
S
Q
V
C
F
L
P
E
Site 22
T266
G
G
N
D
G
K
I
T
L
W
D
A
N
S
E
Site 23
S272
I
T
L
W
D
A
N
S
E
V
E
K
K
Q
K
Site 24
S280
E
V
E
K
K
Q
K
S
P
T
K
R
T
H
R
Site 25
T285
Q
K
S
P
T
K
R
T
H
R
K
K
P
K
R
Site 26
T294
R
K
K
P
K
R
G
T
C
T
K
Q
G
G
N
Site 27
S305
Q
G
G
N
T
N
A
S
V
T
D
E
E
E
H
Site 28
S351
A
D
Q
T
S
C
I
S
V
Y
P
L
N
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation