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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADCK2
Full Name:
Uncharacterized aarF domain-containing protein kinase 2
Alias:
Type:
Mass (Da):
68982
Number AA:
626
UniProt ID:
Q7Z695
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
F
E
L
R
Q
G
L
S
L
L
R
P
S
E
C
Site 2
S31
G
L
S
L
L
R
P
S
E
C
P
R
D
A
R
Site 3
S66
E
G
A
P
D
V
L
S
R
R
R
V
R
C
S
Site 4
S73
S
R
R
R
V
R
C
S
G
A
A
G
A
G
P
Site 5
S83
A
G
A
G
P
A
E
S
L
P
R
A
G
P
L
Site 6
T138
L
H
L
L
L
K
A
T
E
T
S
G
P
T
Y
Site 7
T140
L
L
L
K
A
T
E
T
S
G
P
T
Y
I
K
Site 8
Y145
T
E
T
S
G
P
T
Y
I
K
L
G
Q
W
A
Site 9
S153
I
K
L
G
Q
W
A
S
T
R
R
D
L
F
S
Site 10
T154
K
L
G
Q
W
A
S
T
R
R
D
L
F
S
E
Site 11
S160
S
T
R
R
D
L
F
S
E
A
F
C
A
Q
F
Site 12
T175
S
K
L
H
V
R
V
T
P
H
P
W
T
H
T
Site 13
T180
R
V
T
P
H
P
W
T
H
T
E
R
F
L
R
Site 14
T182
T
P
H
P
W
T
H
T
E
R
F
L
R
Q
A
Site 15
S196
A
F
G
D
D
W
G
S
I
L
S
F
E
N
R
Site 16
S199
D
D
W
G
S
I
L
S
F
E
N
R
E
P
V
Site 17
S208
E
N
R
E
P
V
G
S
G
C
V
A
Q
V
Y
Site 18
Y218
V
A
Q
V
Y
K
A
Y
A
N
T
A
F
L
E
Site 19
S228
T
A
F
L
E
T
D
S
V
Q
R
L
G
R
A
Site 20
S236
V
Q
R
L
G
R
A
S
C
L
P
P
F
S
H
Site 21
Y256
G
L
R
E
L
F
G
Y
L
G
N
G
R
K
P
Site 22
S271
P
E
N
L
A
D
Q
S
F
L
E
R
L
L
L
Site 23
S286
P
K
A
D
L
V
G
S
N
A
G
V
S
R
A
Site 24
S291
V
G
S
N
A
G
V
S
R
A
Q
V
P
G
H
Site 25
Y365
V
Q
Q
I
D
L
R
Y
E
A
Q
N
L
E
H
Site 26
T387
V
K
A
V
K
F
P
T
P
L
R
P
F
V
T
Site 27
Y402
R
E
V
L
V
E
T
Y
E
E
S
V
P
V
S
Site 28
S405
L
V
E
T
Y
E
E
S
V
P
V
S
S
Y
Q
Site 29
S409
Y
E
E
S
V
P
V
S
S
Y
Q
Q
A
G
I
Site 30
S410
E
E
S
V
P
V
S
S
Y
Q
Q
A
G
I
P
Site 31
Y411
E
S
V
P
V
S
S
Y
Q
Q
A
G
I
P
V
Site 32
S462
G
A
N
G
L
S
S
S
Q
E
A
Q
L
Q
Q
Site 33
S534
I
L
H
H
A
R
A
S
E
C
R
D
V
E
G
Site 34
T544
R
D
V
E
G
F
K
T
E
M
A
M
L
V
T
Site 35
T557
V
T
Q
A
R
K
N
T
I
T
L
E
K
L
H
Site 36
T559
Q
A
R
K
N
T
I
T
L
E
K
L
H
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation