KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ARHGAP13
Full Name:
SLIT-ROBO Rho GTPase-activating protein 1
Alias:
KIAA1304; Rho GTPase-activating protein 13; Rho-GTPase-activating protein 13; SLIT-ROBO Rho GTPase activating protein 1; SRGAP1; SRGP1
Type:
GTPase-activating protein for G protein
Mass (Da):
124264
Number AA:
1085
UniProt ID:
Q7Z6B7
International Prot ID:
IPI00376259
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005096
GO:0005099
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
GO:0007154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
D
K
E
I
I
A
E
Y
E
S
Q
V
K
E
I
Site 2
S19
E
I
I
A
E
Y
E
S
Q
V
K
E
I
R
A
Site 3
Y63
K
A
E
I
E
T
E
Y
S
R
N
L
E
K
L
Site 4
S64
A
E
I
E
T
E
Y
S
R
N
L
E
K
L
A
Site 5
T78
A
E
R
F
M
A
K
T
R
S
T
K
D
H
Q
Site 6
S80
R
F
M
A
K
T
R
S
T
K
D
H
Q
Q
Y
Site 7
T81
F
M
A
K
T
R
S
T
K
D
H
Q
Q
Y
K
Site 8
S95
K
K
D
Q
N
L
L
S
P
V
N
C
W
Y
L
Site 9
S111
L
N
Q
V
R
R
E
S
K
D
H
A
T
L
S
Site 10
T116
R
E
S
K
D
H
A
T
L
S
D
I
Y
L
N
Site 11
S118
S
K
D
H
A
T
L
S
D
I
Y
L
N
N
V
Site 12
S136
F
M
Q
I
S
E
D
S
T
R
M
F
K
K
S
Site 13
T137
M
Q
I
S
E
D
S
T
R
M
F
K
K
S
K
Site 14
S143
S
T
R
M
F
K
K
S
K
E
I
A
F
Q
L
Site 15
Y162
M
K
V
L
N
E
L
Y
T
V
M
K
T
Y
H
Site 16
T163
K
V
L
N
E
L
Y
T
V
M
K
T
Y
H
M
Site 17
Y171
V
M
K
T
Y
H
M
Y
H
A
E
S
I
S
A
Site 18
S175
Y
H
M
Y
H
A
E
S
I
S
A
E
S
K
L
Site 19
S213
E
E
R
H
Q
R
R
S
S
V
K
K
I
E
K
Site 20
S214
E
R
H
Q
R
R
S
S
V
K
K
I
E
K
M
Site 21
Y229
K
E
K
R
Q
A
K
Y
S
E
N
K
L
K
S
Site 22
S230
E
K
R
Q
A
K
Y
S
E
N
K
L
K
S
I
Site 23
S236
Y
S
E
N
K
L
K
S
I
K
A
R
N
E
Y
Site 24
Y243
S
I
K
A
R
N
E
Y
L
L
T
L
E
A
T
Site 25
T246
A
R
N
E
Y
L
L
T
L
E
A
T
N
A
S
Site 26
Y257
T
N
A
S
V
F
K
Y
Y
I
H
D
L
S
D
Site 27
Y273
I
D
C
C
D
L
G
Y
H
A
S
L
N
R
A
Site 28
S276
C
D
L
G
Y
H
A
S
L
N
R
A
L
R
T
Site 29
Y284
L
N
R
A
L
R
T
Y
L
S
A
E
Y
N
L
Site 30
S286
R
A
L
R
T
Y
L
S
A
E
Y
N
L
E
T
Site 31
T293
S
A
E
Y
N
L
E
T
S
R
H
E
G
L
D
Site 32
S313
V
D
N
L
E
P
R
S
D
K
Q
R
F
M
E
Site 33
Y322
K
Q
R
F
M
E
M
Y
P
A
A
F
C
P
P
Site 34
Y359
Q
A
E
L
M
L
R
Y
Q
Q
L
Q
S
R
L
Site 35
T368
Q
L
Q
S
R
L
A
T
L
K
I
E
N
E
E
Site 36
T379
E
N
E
E
V
K
K
T
T
E
A
T
L
Q
T
Site 37
T392
Q
T
I
Q
D
M
V
T
I
E
D
Y
D
V
S
Site 38
Y396
D
M
V
T
I
E
D
Y
D
V
S
E
C
F
Q
Site 39
S405
V
S
E
C
F
Q
H
S
R
S
T
E
S
V
K
Site 40
S407
E
C
F
Q
H
S
R
S
T
E
S
V
K
S
T
Site 41
T408
C
F
Q
H
S
R
S
T
E
S
V
K
S
T
V
Site 42
S410
Q
H
S
R
S
T
E
S
V
K
S
T
V
S
E
Site 43
S413
R
S
T
E
S
V
K
S
T
V
S
E
T
Y
L
Site 44
T414
S
T
E
S
V
K
S
T
V
S
E
T
Y
L
S
Site 45
S416
E
S
V
K
S
T
V
S
E
T
Y
L
S
K
P
Site 46
Y419
K
S
T
V
S
E
T
Y
L
S
K
P
S
I
A
Site 47
S421
T
V
S
E
T
Y
L
S
K
P
S
I
A
K
R
Site 48
Y439
Q
Q
E
T
E
Q
F
Y
F
M
K
L
R
E
Y
Site 49
Y446
Y
F
M
K
L
R
E
Y
L
E
G
S
N
L
I
Site 50
T454
L
E
G
S
N
L
I
T
K
L
Q
A
K
H
D
Site 51
Y475
G
E
G
H
R
A
E
Y
M
T
T
R
P
P
N
Site 52
T477
G
H
R
A
E
Y
M
T
T
R
P
P
N
V
P
Site 53
T478
H
R
A
E
Y
M
T
T
R
P
P
N
V
P
P
Site 54
S493
K
P
Q
K
H
R
K
S
R
P
R
S
Q
Y
N
Site 55
S497
H
R
K
S
R
P
R
S
Q
Y
N
T
K
L
F
Site 56
Y499
K
S
R
P
R
S
Q
Y
N
T
K
L
F
N
G
Site 57
T501
R
P
R
S
Q
Y
N
T
K
L
F
N
G
D
L
Site 58
T510
L
F
N
G
D
L
E
T
F
V
K
D
S
G
Q
Site 59
S544
H
Q
G
I
F
R
V
S
G
S
Q
V
E
V
N
Site 60
S556
E
V
N
D
I
K
N
S
F
E
R
G
E
N
P
Site 61
S569
N
P
L
A
D
D
Q
S
N
H
D
I
N
S
V
Site 62
S575
Q
S
N
H
D
I
N
S
V
A
G
V
L
K
L
Site 63
S602
E
R
F
N
D
L
I
S
C
I
R
I
D
N
L
Site 64
Y610
C
I
R
I
D
N
L
Y
E
R
A
L
H
I
R
Site 65
S645
L
N
H
L
S
Q
Y
S
D
E
N
M
M
D
P
Site 66
Y653
D
E
N
M
M
D
P
Y
N
L
A
I
C
F
G
Site 67
Y705
K
E
L
D
G
P
V
Y
E
K
C
M
A
G
D
Site 68
Y714
K
C
M
A
G
D
D
Y
C
D
S
P
Y
S
E
Site 69
S717
A
G
D
D
Y
C
D
S
P
Y
S
E
H
G
T
Site 70
Y719
D
D
Y
C
D
S
P
Y
S
E
H
G
T
L
E
Site 71
S720
D
Y
C
D
S
P
Y
S
E
H
G
T
L
E
E
Site 72
T724
S
P
Y
S
E
H
G
T
L
E
E
V
D
Q
D
Site 73
T734
E
V
D
Q
D
A
G
T
E
P
H
T
S
E
D
Site 74
S739
A
G
T
E
P
H
T
S
E
D
E
C
E
P
I
Site 75
Y754
E
A
I
A
K
F
D
Y
V
G
R
S
A
R
E
Site 76
S758
K
F
D
Y
V
G
R
S
A
R
E
L
S
F
K
Site 77
S763
G
R
S
A
R
E
L
S
F
K
K
G
A
S
L
Site 78
Y773
K
G
A
S
L
L
L
Y
H
R
A
S
E
D
W
Site 79
S777
L
L
L
Y
H
R
A
S
E
D
W
W
E
G
R
Site 80
Y796
D
G
L
V
P
H
Q
Y
I
V
V
Q
D
M
D
Site 81
T805
V
V
Q
D
M
D
D
T
F
S
D
T
L
S
Q
Site 82
S807
Q
D
M
D
D
T
F
S
D
T
L
S
Q
K
A
Site 83
T809
M
D
D
T
F
S
D
T
L
S
Q
K
A
D
S
Site 84
S811
D
T
F
S
D
T
L
S
Q
K
A
D
S
E
A
Site 85
S816
T
L
S
Q
K
A
D
S
E
A
S
S
G
P
V
Site 86
S819
Q
K
A
D
S
E
A
S
S
G
P
V
T
E
D
Site 87
S820
K
A
D
S
E
A
S
S
G
P
V
T
E
D
K
Site 88
T824
E
A
S
S
G
P
V
T
E
D
K
S
S
S
K
Site 89
S828
G
P
V
T
E
D
K
S
S
S
K
D
M
N
S
Site 90
S829
P
V
T
E
D
K
S
S
S
K
D
M
N
S
P
Site 91
S830
V
T
E
D
K
S
S
S
K
D
M
N
S
P
T
Site 92
S835
S
S
S
K
D
M
N
S
P
T
D
R
H
P
D
Site 93
T837
S
K
D
M
N
S
P
T
D
R
H
P
D
G
Y
Site 94
Y844
T
D
R
H
P
D
G
Y
L
A
R
Q
R
K
R
Site 95
T864
P
V
R
R
P
G
R
T
S
D
G
H
C
P
L
Site 96
S865
V
R
R
P
G
R
T
S
D
G
H
C
P
L
H
Site 97
S878
L
H
P
P
H
A
L
S
N
S
S
V
D
L
G
Site 98
S880
P
P
H
A
L
S
N
S
S
V
D
L
G
S
P
Site 99
S881
P
H
A
L
S
N
S
S
V
D
L
G
S
P
S
Site 100
S886
N
S
S
V
D
L
G
S
P
S
L
A
S
H
P
Site 101
S888
S
V
D
L
G
S
P
S
L
A
S
H
P
R
G
Site 102
S891
L
G
S
P
S
L
A
S
H
P
R
G
L
L
Q
Site 103
S906
N
R
G
L
N
N
D
S
P
E
R
R
R
R
P
Site 104
S917
R
R
R
P
G
H
G
S
L
T
N
I
S
R
H
Site 105
T919
R
P
G
H
G
S
L
T
N
I
S
R
H
D
S
Site 106
S922
H
G
S
L
T
N
I
S
R
H
D
S
L
K
K
Site 107
S926
T
N
I
S
R
H
D
S
L
K
K
I
D
S
P
Site 108
S932
D
S
L
K
K
I
D
S
P
P
I
R
R
S
T
Site 109
S938
D
S
P
P
I
R
R
S
T
S
S
G
Q
Y
T
Site 110
T939
S
P
P
I
R
R
S
T
S
S
G
Q
Y
T
G
Site 111
S940
P
P
I
R
R
S
T
S
S
G
Q
Y
T
G
F
Site 112
S941
P
I
R
R
S
T
S
S
G
Q
Y
T
G
F
N
Site 113
Y944
R
S
T
S
S
G
Q
Y
T
G
F
N
D
H
K
Site 114
T945
S
T
S
S
G
Q
Y
T
G
F
N
D
H
K
P
Site 115
T957
H
K
P
L
D
P
E
T
I
A
Q
D
I
E
E
Site 116
T965
I
A
Q
D
I
E
E
T
M
N
T
A
L
N
E
Site 117
T968
D
I
E
E
T
M
N
T
A
L
N
E
L
R
E
Site 118
S980
L
R
E
L
E
R
Q
S
T
A
K
H
A
P
D
Site 119
T981
R
E
L
E
R
Q
S
T
A
K
H
A
P
D
V
Site 120
T992
A
P
D
V
V
L
D
T
L
E
Q
V
K
N
S
Site 121
S999
T
L
E
Q
V
K
N
S
P
T
P
A
T
S
T
Site 122
T1001
E
Q
V
K
N
S
P
T
P
A
T
S
T
E
S
Site 123
T1004
K
N
S
P
T
P
A
T
S
T
E
S
L
S
P
Site 124
S1005
N
S
P
T
P
A
T
S
T
E
S
L
S
P
L
Site 125
T1006
S
P
T
P
A
T
S
T
E
S
L
S
P
L
H
Site 126
S1008
T
P
A
T
S
T
E
S
L
S
P
L
H
N
V
Site 127
S1010
A
T
S
T
E
S
L
S
P
L
H
N
V
A
L
Site 128
S1020
H
N
V
A
L
R
S
S
E
P
Q
I
R
R
S
Site 129
S1027
S
E
P
Q
I
R
R
S
T
S
S
S
S
D
T
Site 130
T1028
E
P
Q
I
R
R
S
T
S
S
S
S
D
T
M
Site 131
S1029
P
Q
I
R
R
S
T
S
S
S
S
D
T
M
S
Site 132
S1030
Q
I
R
R
S
T
S
S
S
S
D
T
M
S
T
Site 133
S1031
I
R
R
S
T
S
S
S
S
D
T
M
S
T
F
Site 134
S1032
R
R
S
T
S
S
S
S
D
T
M
S
T
F
K
Site 135
T1034
S
T
S
S
S
S
D
T
M
S
T
F
K
P
M
Site 136
S1036
S
S
S
S
D
T
M
S
T
F
K
P
M
V
A
Site 137
T1037
S
S
S
D
T
M
S
T
F
K
P
M
V
A
P
Site 138
T1065
K
P
A
V
L
P
K
T
N
P
T
I
G
P
A
Site 139
T1068
V
L
P
K
T
N
P
T
I
G
P
A
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation