PhosphoNET

           
Protein Info 
   
Short Name:  AIDA-1b
Full Name:  Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Alias:  AIDA-1; Amyloid-beta protein intracellular domain-associated protein 1; ANKS1B; ANKS2; Ankyrin repeat and sterile alpha motif domain containing 1B; Cajalin-2; E2A-PBX1-associated protein; EB-1
Type:  Plasma membrane, Cytoplasm, Nucleus, Postsynaptic membrane, Synapse, Cell projection, Cell junction protein
Mass (Da):  138185
Number AA:  1249
UniProt ID:  Q7Z6G8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0015030  GO:0030054  GO:0005737 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T55RGPNVNCTDSSGYTA
Site 2S57PNVNCTDSSGYTALH
Site 3Y93NVADNKGYFPIHLAA
Site 4S119IHHGPSHSRVNEQNN
Site 5T155LEELTDPTIRNSKLE
Site 6S159TDPTIRNSKLETPLD
Site 7T163IRNSKLETPLDLAAL
Site 8T196SCNTRKHTPLHLAAR
Site 9S221LEAGMDVSCQTEKGS
Site 10S257IDANIKDSLGRTVLD
Site 11T261IKDSLGRTVLDILKE
Site 12S271DILKEHPSQKSLQIA
Site 13S274KEHPSQKSLQIATLL
Site 14T293EGVGKYATVLEEPVQ
Site 15T304EPVQEDATQETHISS
Site 16S310ATQETHISSPVESPS
Site 17S311TQETHISSPVESPSQ
Site 18S315HISSPVESPSQKTKS
Site 19S317SSPVESPSQKTKSET
Site 20S322SPSQKTKSETVTGEL
Site 21T324SQKTKSETVTGELSK
Site 22T326KTKSETVTGELSKLL
Site 23Y344KLCQEKDYSFEDLCH
Site 24T352SFEDLCHTISDHYLD
Site 25S354EDLCHTISDHYLDNL
Site 26Y357CHTISDHYLDNLSKI
Site 27S362DHYLDNLSKISEEEL
Site 28S365LDNLSKISEEELGKN
Site 29S374EELGKNGSQSVRTSS
Site 30S376LGKNGSQSVRTSSTI
Site 31S380GSQSVRTSSTINLSP
Site 32S381SQSVRTSSTINLSPG
Site 33T382QSVRTSSTINLSPGE
Site 34S386TSSTINLSPGEVEEE
Site 35T399EEDDDENTCGPSGLW
Site 36T410SGLWEALTPCNGCRN
Site 37S427FPMLAQESYPKKRNY
Site 38Y428PMLAQESYPKKRNYT
Site 39Y434SYPKKRNYTMEIVPS
Site 40T435YPKKRNYTMEIVPSA
Site 41S443MEIVPSASLDTFPSE
Site 42T446VPSASLDTFPSENEN
Site 43S469AVTKKPCSLEIARAP
Site 44S477LEIARAPSPRTDNAS
Site 45T480ARAPSPRTDNASEVA
Site 46S484SPRTDNASEVAVTTP
Site 47T489NASEVAVTTPGTSNH
Site 48T490ASEVAVTTPGTSNHR
Site 49S494AVTTPGTSNHRNSST
Site 50S499GTSNHRNSSTGPTPD
Site 51S500TSNHRNSSTGPTPDC
Site 52T504RNSSTGPTPDCSPPS
Site 53S508TGPTPDCSPPSPDTA
Site 54S511TPDCSPPSPDTALKN
Site 55T514CSPPSPDTALKNIVK
Site 56T531RPQPKQRTSIVSSLD
Site 57S532PQPKQRTSIVSSLDF
Site 58S535KQRTSIVSSLDFHRM
Site 59S536QRTSIVSSLDFHRMN
Site 60Y548RMNHNQEYFEINTST
Site 61T555YFEINTSTGCTSFTA
Site 62S559NTSTGCTSFTASPPA
Site 63T561STGCTSFTASPPASP
Site 64S563GCTSFTASPPASPPT
Site 65S567FTASPPASPPTSSVG
Site 66T570SPPASPPTSSVGTTE
Site 67S571PPASPPTSSVGTTEV
Site 68S572PASPPTSSVGTTEVK
Site 69T575PPTSSVGTTEVKNEG
Site 70T576PTSSVGTTEVKNEGT
Site 71S590TNHTDDLSRQDDNDP
Site 72S614AGLLHGSSPACESPE
Site 73S619GSSPACESPENPFHL
Site 74Y627PENPFHLYGKREQCE
Site 75S641EKGQDEVSLANSPLP
Site 76S645DEVSLANSPLPFKQS
Site 77S652SPLPFKQSPIENNSE
Site 78S692HTIVGTRSTRSGSRN
Site 79T693TIVGTRSTRSGSRNG
Site 80S695VGTRSTRSGSRNGDQ
Site 81S697TRSTRSGSRNGDQWV
Site 82S733ALIDMHLSKSVSKSD
Site 83S735IDMHLSKSVSKSDSD
Site 84S737MHLSKSVSKSDSDLI
Site 85S739LSKSVSKSDSDLIAY
Site 86S741KSVSKSDSDLIAYPS
Site 87Y746SDSDLIAYPSNEKTS
Site 88S748SDLIAYPSNEKTSRV
Site 89T752AYPSNEKTSRVNWSE
Site 90S758KTSRVNWSESSTAEH
Site 91S760SRVNWSESSTAEHSS
Site 92S761RVNWSESSTAEHSSK
Site 93T762VNWSESSTAEHSSKG
Site 94S767SSTAEHSSKGNSERT
Site 95S771EHSSKGNSERTPSFT
Site 96T774SKGNSERTPSFTSEW
Site 97S776GNSERTPSFTSEWEE
Site 98T778SERTPSFTSEWEEID
Site 99S789EEIDKIMSSIDVGIN
Site 100S790EIDKIMSSIDVGINN
Site 101T806LKEMNGETTRPRCPV
Site 102T815RPRCPVQTVGQWLES
Site 103Y828ESIGLPQYENHLMAN
Site 104S861LEIGILNSGHRQRIL
Site 105Y885RPIGHDGYHPTSVAE
Site 106S889HDGYHPTSVAEWLDS
Site 107S896SVAEWLDSIELGDYT
Site 108Y902DSIELGDYTKAFLIN
Site 109S943HRKRILASLGDRLHD
Site 110S959PPQKPPRSITLREPS
Site 111T961QKPPRSITLREPSGN
Site 112S966SITLREPSGNHTPPQ
Site 113T970REPSGNHTPPQLSPS
Site 114S975NHTPPQLSPSLSQST
Site 115S977TPPQLSPSLSQSTYT
Site 116S979PQLSPSLSQSTYTTG
Site 117S981LSPSLSQSTYTTGGS
Site 118Y983PSLSQSTYTTGGSLD
Site 119T984SLSQSTYTTGGSLDV
Site 120T985LSQSTYTTGGSLDVP
Site 121S988STYTTGGSLDVPHII
Site 122Y1008RRRRNENYFDDIPRS
Site 123S1015YFDDIPRSKLERQMA
Site 124T1024LERQMAQTGDWGEPS
Site 125S1031TGDWGEPSITLRPPN
Site 126T1033DWGEPSITLRPPNEA
Site 127S1043PPNEATASTPVQYWQ
Site 128T1044PNEATASTPVQYWQH
Site 129Y1048TASTPVQYWQHHPEK
Site 130T1079LIKELRGTESTQDAC
Site 131S1081KELRGTESTQDACAK
Site 132T1082ELRGTESTQDACAKM
Site 133S1135EHEIRNISCAAQDPE
Site 134S1145AQDPEDLSTFAYITK
Site 135T1146QDPEDLSTFAYITKD
Site 136Y1149EDLSTFAYITKDLKS
Site 137Y1160DLKSNHHYCHVFTAF
Site 138S1199QARKGGHSSTLPESF
Site 139S1200ARKGGHSSTLPESFE
Site 140T1201RKGGHSSTLPESFEN
Site 141S1205HSSTLPESFENKPSK
Site 142S1211ESFENKPSKPIPKPR
Site 143S1220PIPKPRVSIRKSVDL
Site 144S1224PRVSIRKSVDLLHAS
Site 145S1231SVDLLHASHTGQEPS
Site 146S1238SHTGQEPSERHTEEA
Site 147T1242QEPSERHTEEALRKF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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