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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARHGAP30
Full Name:
Rho GTPase-activating protein 30
Alias:
FLJ00267; RHG30; Rho GTPase activating protein 30; Rho-type GTPase-activating protein 30
Type:
GTPase-activating protein for G protein
Mass (Da):
95528
Number AA:
890
UniProt ID:
Q7Z6I6
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
Q
K
G
K
K
K
G
S
A
K
E
R
V
F
G
Site 2
S39
E
V
P
Q
V
L
K
S
C
A
E
F
V
E
E
Site 3
S57
V
D
G
I
Y
R
L
S
G
V
S
S
N
I
Q
Site 4
S60
I
Y
R
L
S
G
V
S
S
N
I
Q
K
L
R
Site 5
S61
Y
R
L
S
G
V
S
S
N
I
Q
K
L
R
Q
Site 6
S72
K
L
R
Q
E
F
E
S
E
R
K
P
D
L
R
Site 7
Y83
P
D
L
R
R
D
V
Y
L
Q
D
I
H
C
V
Site 8
Y97
V
S
S
L
C
K
A
Y
F
R
E
L
P
D
P
Site 9
T107
E
L
P
D
P
L
L
T
Y
R
L
Y
D
K
F
Site 10
Y142
R
E
L
P
V
P
N
Y
R
T
L
E
F
L
M
Site 11
S157
R
H
L
V
H
M
A
S
F
S
A
Q
T
N
M
Site 12
S180
W
A
P
N
L
L
R
S
K
D
I
E
A
S
G
Site 13
S227
L
S
G
G
E
V
E
S
G
W
R
S
L
P
G
Site 14
S231
E
V
E
S
G
W
R
S
L
P
G
T
R
A
S
Site 15
T235
G
W
R
S
L
P
G
T
R
A
S
G
S
P
E
Site 16
S238
S
L
P
G
T
R
A
S
G
S
P
E
D
L
M
Site 17
S240
P
G
T
R
A
S
G
S
P
E
D
L
M
P
R
Site 18
S255
P
L
P
Y
H
L
P
S
I
L
Q
A
G
D
G
Site 19
Y269
G
P
P
Q
M
R
P
Y
H
T
I
I
E
I
A
Site 20
S283
A
E
H
K
R
K
G
S
L
K
V
R
K
W
R
Site 21
S291
L
K
V
R
K
W
R
S
I
F
N
L
G
R
S
Site 22
T302
L
G
R
S
G
H
E
T
K
R
K
L
P
R
G
Site 23
S317
A
E
D
R
E
D
K
S
N
K
G
T
L
R
P
Site 24
T321
E
D
K
S
N
K
G
T
L
R
P
A
K
S
M
Site 25
S327
G
T
L
R
P
A
K
S
M
D
S
L
S
A
A
Site 26
S330
R
P
A
K
S
M
D
S
L
S
A
A
A
G
A
Site 27
S332
A
K
S
M
D
S
L
S
A
A
A
G
A
S
D
Site 28
S348
P
E
G
L
V
G
P
S
S
P
R
P
S
P
L
Site 29
S349
E
G
L
V
G
P
S
S
P
R
P
S
P
L
L
Site 30
S353
G
P
S
S
P
R
P
S
P
L
L
P
E
S
L
Site 31
S359
P
S
P
L
L
P
E
S
L
E
N
D
S
I
E
Site 32
S364
P
E
S
L
E
N
D
S
I
E
A
A
E
G
E
Site 33
S384
E
A
L
G
G
T
N
S
E
P
G
T
P
R
A
Site 34
T388
G
T
N
S
E
P
G
T
P
R
A
G
R
S
A
Site 35
S394
G
T
P
R
A
G
R
S
A
I
R
A
G
G
S
Site 36
S401
S
A
I
R
A
G
G
S
S
R
A
E
R
C
A
Site 37
S402
A
I
R
A
G
G
S
S
R
A
E
R
C
A
G
Site 38
Y416
G
V
H
I
S
D
P
Y
N
V
N
L
P
L
H
Site 39
S457
P
A
L
Q
H
R
P
S
P
A
S
G
P
G
P
Site 40
S460
Q
H
R
P
S
P
A
S
G
P
G
P
G
P
G
Site 41
S480
P
D
E
K
L
E
A
S
P
A
S
S
P
L
A
Site 42
S484
L
E
A
S
P
A
S
S
P
L
A
D
S
G
P
Site 43
S489
A
S
S
P
L
A
D
S
G
P
D
D
L
A
P
Site 44
S501
L
A
P
A
L
E
D
S
L
S
Q
E
V
Q
D
Site 45
S503
P
A
L
E
D
S
L
S
Q
E
V
Q
D
S
F
Site 46
S509
L
S
Q
E
V
Q
D
S
F
S
F
L
E
D
S
Site 47
S511
Q
E
V
Q
D
S
F
S
F
L
E
D
S
S
S
Site 48
S516
S
F
S
F
L
E
D
S
S
S
S
E
P
E
W
Site 49
S517
F
S
F
L
E
D
S
S
S
S
E
P
E
W
V
Site 50
S518
S
F
L
E
D
S
S
S
S
E
P
E
W
V
G
Site 51
S542
E
A
A
G
A
A
F
S
P
G
E
D
D
P
G
Site 52
Y552
E
D
D
P
G
M
G
Y
L
E
E
L
L
G
V
Site 53
S567
G
P
Q
V
E
E
F
S
V
E
P
P
L
D
D
Site 54
S576
E
P
P
L
D
D
L
S
L
D
E
A
Q
F
V
Site 55
S593
P
S
C
C
S
L
D
S
A
G
P
R
P
E
V
Site 56
S611
N
G
E
E
V
F
L
S
A
Y
D
D
L
S
P
Site 57
S617
L
S
A
Y
D
D
L
S
P
L
L
G
P
K
P
Site 58
S630
K
P
P
I
W
K
G
S
G
S
L
E
G
E
A
Site 59
S632
P
I
W
K
G
S
G
S
L
E
G
E
A
A
G
Site 60
T678
I
R
E
E
A
E
G
T
P
E
T
K
V
E
A
Site 61
S698
D
R
G
E
A
G
G
S
Q
E
T
K
V
R
L
Site 62
S709
K
V
R
L
R
E
G
S
R
E
E
T
E
A
K
Site 63
T713
R
E
G
S
R
E
E
T
E
A
K
E
E
K
S
Site 64
S728
K
G
Q
K
K
A
D
S
M
E
A
K
G
V
E
Site 65
Y742
E
E
P
G
G
D
E
Y
T
D
E
K
E
K
E
Site 66
T743
E
P
G
G
D
E
Y
T
D
E
K
E
K
E
I
Site 67
Y807
K
G
Q
R
E
K
G
Y
H
E
A
R
K
D
Q
Site 68
S820
D
Q
G
D
G
E
D
S
R
S
P
E
A
A
T
Site 69
S822
G
D
G
E
D
S
R
S
P
E
A
A
T
E
G
Site 70
S835
E
G
G
A
G
E
V
S
K
E
R
E
S
G
D
Site 71
S840
E
V
S
K
E
R
E
S
G
D
G
E
A
E
G
Site 72
Y855
D
Q
R
A
G
G
Y
Y
L
E
E
D
T
L
S
Site 73
T860
G
Y
Y
L
E
E
D
T
L
S
E
G
S
G
V
Site 74
S862
Y
L
E
E
D
T
L
S
E
G
S
G
V
A
S
Site 75
S865
E
D
T
L
S
E
G
S
G
V
A
S
L
E
V
Site 76
S869
S
E
G
S
G
V
A
S
L
E
V
D
C
A
K
Site 77
S882
A
K
E
G
N
P
H
S
S
E
M
E
E
V
A
Site 78
S883
K
E
G
N
P
H
S
S
E
M
E
E
V
A
P
Site 79
S905
M
E
P
E
G
Q
P
S
P
D
G
C
L
C
P
Site 80
S926
G
V
G
M
R
L
A
S
T
L
V
Q
V
Q
Q
Site 81
S936
V
Q
V
Q
Q
V
R
S
V
P
V
V
P
P
K
Site 82
T974
R
P
G
R
L
D
G
T
P
G
E
R
A
W
G
Site 83
S982
P
G
E
R
A
W
G
S
R
A
S
R
S
S
W
Site 84
S985
R
A
W
G
S
R
A
S
R
S
S
W
R
N
G
Site 85
S987
W
G
S
R
A
S
R
S
S
W
R
N
G
G
S
Site 86
S988
G
S
R
A
S
R
S
S
W
R
N
G
G
S
L
Site 87
S994
S
S
W
R
N
G
G
S
L
S
F
D
A
A
V
Site 88
S996
W
R
N
G
G
S
L
S
F
D
A
A
V
A
L
Site 89
T1010
L
A
R
D
R
Q
R
T
E
A
Q
G
V
R
R
Site 90
T1018
E
A
Q
G
V
R
R
T
Q
T
C
T
E
G
G
Site 91
T1020
Q
G
V
R
R
T
Q
T
C
T
E
G
G
D
Y
Site 92
T1022
V
R
R
T
Q
T
C
T
E
G
G
D
Y
C
L
Site 93
Y1027
T
C
T
E
G
G
D
Y
C
L
I
P
R
T
S
Site 94
S1037
I
P
R
T
S
P
C
S
M
I
S
A
H
S
P
Site 95
S1040
T
S
P
C
S
M
I
S
A
H
S
P
R
P
L
Site 96
S1048
A
H
S
P
R
P
L
S
C
L
E
L
P
S
E
Site 97
S1054
L
S
C
L
E
L
P
S
E
G
A
E
G
S
G
Site 98
S1060
P
S
E
G
A
E
G
S
G
S
R
S
R
L
S
Site 99
S1062
E
G
A
E
G
S
G
S
R
S
R
L
S
L
P
Site 100
S1064
A
E
G
S
G
S
R
S
R
L
S
L
P
P
R
Site 101
S1067
S
G
S
R
S
R
L
S
L
P
P
R
E
P
Q
Site 102
S1081
Q
V
P
D
P
L
L
S
S
Q
R
R
S
Y
A
Site 103
S1082
V
P
D
P
L
L
S
S
Q
R
R
S
Y
A
F
Site 104
S1086
L
L
S
S
Q
R
R
S
Y
A
F
E
T
Q
A
Site 105
Y1087
L
S
S
Q
R
R
S
Y
A
F
E
T
Q
A
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation