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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRASP
Full Name:
General receptor for phosphoinositides 1-associated scaffold protein
Alias:
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein; GRP1-associated scaffold protein; Tamalin
Type:
Adaptor/scaffold
Mass (Da):
42623
Number AA:
395
UniProt ID:
Q7Z6J2
International Prot ID:
IPI00333325
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0048471
GO:0045211
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
Q
K
E
E
A
A
A
T
P
D
P
A
A
R
T
Site 2
T25
T
P
D
P
A
A
R
T
P
D
S
E
V
A
P
Site 3
S28
P
A
A
R
T
P
D
S
E
V
A
P
A
A
P
Site 4
T47
G
P
P
A
A
A
A
T
P
G
P
P
A
D
E
Site 5
Y56
G
P
P
A
D
E
L
Y
A
A
L
E
D
Y
H
Site 6
Y62
L
Y
A
A
L
E
D
Y
H
P
A
E
L
Y
R
Site 7
Y68
D
Y
H
P
A
E
L
Y
R
A
L
A
V
S
G
Site 8
S74
L
Y
R
A
L
A
V
S
G
G
T
L
P
R
R
Site 9
S84
T
L
P
R
R
K
G
S
G
F
R
W
K
N
L
Site 10
S92
G
F
R
W
K
N
L
S
Q
S
P
E
Q
Q
R
Site 11
S94
R
W
K
N
L
S
Q
S
P
E
Q
Q
R
K
V
Site 12
T111
L
E
K
E
D
N
Q
T
F
G
F
E
I
Q
T
Site 13
Y119
F
G
F
E
I
Q
T
Y
G
L
H
H
R
E
E
Site 14
S157
T
P
G
D
T
I
A
S
V
N
G
L
N
V
E
Site 15
T186
G
N
V
L
R
L
E
T
L
Y
G
T
S
I
R
Site 16
Y203
E
L
E
A
R
L
Q
Y
L
K
Q
T
L
Y
E
Site 17
Y209
Q
Y
L
K
Q
T
L
Y
E
K
W
G
E
Y
R
Site 18
S217
E
K
W
G
E
Y
R
S
L
M
V
Q
E
Q
R
Site 19
S235
G
L
V
V
K
D
P
S
I
Y
D
T
L
E
S
Site 20
Y237
V
V
K
D
P
S
I
Y
D
T
L
E
S
V
R
Site 21
T239
K
D
P
S
I
Y
D
T
L
E
S
V
R
S
C
Site 22
S242
S
I
Y
D
T
L
E
S
V
R
S
C
L
Y
G
Site 23
Y285
G
D
A
D
D
A
V
Y
H
T
C
F
F
G
D
Site 24
S293
H
T
C
F
F
G
D
S
E
P
P
A
L
P
P
Site 25
T315
F
G
P
G
P
A
E
T
P
A
V
G
P
G
P
Site 26
S329
P
G
P
R
A
A
L
S
R
S
A
S
V
R
C
Site 27
S331
P
R
A
A
L
S
R
S
A
S
V
R
C
A
G
Site 28
T368
C
G
P
G
L
R
K
T
K
Y
R
S
F
R
R
Site 29
Y370
P
G
L
R
K
T
K
Y
R
S
F
R
R
R
L
Site 30
S372
L
R
K
T
K
Y
R
S
F
R
R
R
L
L
K
Site 31
S387
F
I
P
G
L
N
R
S
L
E
E
E
E
S
Q
Site 32
S393
R
S
L
E
E
E
E
S
Q
L
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation