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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSEN54
Full Name:
tRNA-splicing endonuclease subunit Sen54
Alias:
tRNA-intron endonuclease Sen54
Type:
Mass (Da):
58819
Number AA:
526
UniProt ID:
Q7Z6J9
International Prot ID:
IPI00329143
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006397
GO:0006388
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
R
E
L
F
A
A
R
S
R
S
Q
K
L
P
Q
Site 2
S30
L
F
A
A
R
S
R
S
Q
K
L
P
Q
R
S
Site 3
S37
S
Q
K
L
P
Q
R
S
H
G
P
K
D
F
L
Site 4
S76
Q
R
V
E
R
L
G
S
L
V
A
A
E
W
R
Site 5
S93
E
G
F
V
E
L
K
S
P
A
G
K
F
W
Q
Site 6
S136
F
H
Q
D
L
P
L
S
I
Q
E
A
Y
Q
L
Site 7
Y155
H
T
V
T
F
L
Q
Y
Q
V
F
S
H
L
K
Site 8
Y166
S
H
L
K
R
L
G
Y
V
V
R
R
F
Q
P
Site 9
S174
V
V
R
R
F
Q
P
S
S
V
L
S
P
Y
E
Site 10
S175
V
R
R
F
Q
P
S
S
V
L
S
P
Y
E
R
Site 11
S178
F
Q
P
S
S
V
L
S
P
Y
E
R
Q
L
N
Site 12
Y180
P
S
S
V
L
S
P
Y
E
R
Q
L
N
L
D
Site 13
S189
R
Q
L
N
L
D
A
S
V
Q
H
L
E
D
G
Site 14
S203
G
D
G
K
R
K
R
S
S
S
S
P
R
S
I
Site 15
S204
D
G
K
R
K
R
S
S
S
S
P
R
S
I
N
Site 16
S205
G
K
R
K
R
S
S
S
S
P
R
S
I
N
K
Site 17
S206
K
R
K
R
S
S
S
S
P
R
S
I
N
K
K
Site 18
S209
R
S
S
S
S
P
R
S
I
N
K
K
A
K
A
Site 19
S220
K
A
K
A
L
D
N
S
L
Q
P
K
S
L
A
Site 20
S225
D
N
S
L
Q
P
K
S
L
A
A
S
S
P
P
Site 21
S229
Q
P
K
S
L
A
A
S
S
P
P
P
C
S
Q
Site 22
S230
P
K
S
L
A
A
S
S
P
P
P
C
S
Q
P
Site 23
S235
A
S
S
P
P
P
C
S
Q
P
S
Q
C
P
E
Site 24
S238
P
P
P
C
S
Q
P
S
Q
C
P
E
E
K
P
Site 25
S248
P
E
E
K
P
Q
E
S
S
P
M
K
G
P
G
Site 26
S249
E
E
K
P
Q
E
S
S
P
M
K
G
P
G
G
Site 27
S263
G
P
F
Q
L
L
G
S
L
G
P
S
P
G
P
Site 28
S267
L
L
G
S
L
G
P
S
P
G
P
A
R
E
G
Site 29
S278
A
R
E
G
V
G
C
S
W
E
S
G
R
A
E
Site 30
S281
G
V
G
C
S
W
E
S
G
R
A
E
N
G
V
Site 31
T289
G
R
A
E
N
G
V
T
G
A
G
K
R
R
W
Site 32
S308
I
S
F
P
N
M
A
S
D
S
R
H
T
L
L
Site 33
S310
F
P
N
M
A
S
D
S
R
H
T
L
L
R
A
Site 34
T313
M
A
S
D
S
R
H
T
L
L
R
A
P
A
P
Site 35
T332
A
N
V
A
G
R
E
T
D
A
E
S
W
C
Q
Site 36
S336
G
R
E
T
D
A
E
S
W
C
Q
K
L
N
Q
Site 37
S349
N
Q
R
K
E
N
L
S
R
R
E
R
E
H
H
Site 38
S376
D
P
E
V
Q
R
C
S
S
W
R
E
Y
K
E
Site 39
S377
P
E
V
Q
R
C
S
S
W
R
E
Y
K
E
L
Site 40
Y381
R
C
S
S
W
R
E
Y
K
E
L
L
Q
R
R
Site 41
S393
Q
R
R
Q
V
Q
R
S
Q
R
R
A
P
H
L
Site 42
T406
H
L
W
G
Q
P
V
T
P
L
L
S
P
G
Q
Site 43
S410
Q
P
V
T
P
L
L
S
P
G
Q
A
S
S
P
Site 44
T429
Q
H
I
S
V
L
Q
T
T
H
L
P
D
G
G
Site 45
T460
Y
Q
A
D
A
V
A
T
F
R
K
N
N
P
G
Site 46
Y470
K
N
N
P
G
K
P
Y
A
R
M
C
I
S
G
Site 47
S487
E
P
V
P
D
L
C
S
L
K
R
L
S
Y
Q
Site 48
S492
L
C
S
L
K
R
L
S
Y
Q
S
G
D
V
P
Site 49
Y493
C
S
L
K
R
L
S
Y
Q
S
G
D
V
P
L
Site 50
S511
L
V
D
H
G
D
I
S
F
Y
S
F
R
D
F
Site 51
S514
H
G
D
I
S
F
Y
S
F
R
D
F
T
L
P
Site 52
T519
F
Y
S
F
R
D
F
T
L
P
Q
D
V
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation