KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
THAP5
Full Name:
THAP domain-containing protein 5
Alias:
Type:
Mass (Da):
45416
Number AA:
395
UniProt ID:
Q7Z6K1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
N
N
K
D
R
K
L
S
F
Y
P
F
P
L
H
Site 2
Y26
K
D
R
K
L
S
F
Y
P
F
P
L
H
D
K
Site 3
S47
L
K
N
M
K
R
D
S
W
V
P
S
K
Y
Q
Site 4
Y53
D
S
W
V
P
S
K
Y
Q
F
L
C
S
D
H
Site 5
S58
S
K
Y
Q
F
L
C
S
D
H
F
T
P
D
S
Site 6
T62
F
L
C
S
D
H
F
T
P
D
S
L
D
I
R
Site 7
S65
S
D
H
F
T
P
D
S
L
D
I
R
W
G
I
Site 8
Y74
D
I
R
W
G
I
R
Y
L
K
Q
T
A
V
P
Site 9
S96
D
N
Q
G
K
D
P
S
K
K
K
S
Q
K
K
Site 10
S100
K
D
P
S
K
K
K
S
Q
K
K
N
L
E
D
Site 11
S117
E
V
C
P
K
A
K
S
E
E
S
F
V
L
N
Site 12
S120
P
K
A
K
S
E
E
S
F
V
L
N
E
T
K
Site 13
T133
T
K
K
N
I
V
N
T
D
V
P
H
Q
H
P
Site 14
S145
Q
H
P
E
L
L
H
S
S
S
L
V
K
P
P
Site 15
S147
P
E
L
L
H
S
S
S
L
V
K
P
P
A
P
Site 16
T156
V
K
P
P
A
P
K
T
G
S
I
Q
N
N
M
Site 17
S158
P
P
A
P
K
T
G
S
I
Q
N
N
M
L
T
Site 18
T173
L
N
L
V
K
Q
H
T
G
K
P
E
S
T
L
Site 19
S178
Q
H
T
G
K
P
E
S
T
L
E
T
S
V
N
Site 20
T179
H
T
G
K
P
E
S
T
L
E
T
S
V
N
Q
Site 21
T182
K
P
E
S
T
L
E
T
S
V
N
Q
D
T
G
Site 22
S183
P
E
S
T
L
E
T
S
V
N
Q
D
T
G
R
Site 23
T188
E
T
S
V
N
Q
D
T
G
R
G
G
F
H
T
Site 24
T195
T
G
R
G
G
F
H
T
C
F
E
N
L
N
S
Site 25
T206
N
L
N
S
T
T
I
T
L
T
T
S
N
S
E
Site 26
T208
N
S
T
T
I
T
L
T
T
S
N
S
E
S
I
Site 27
S210
T
T
I
T
L
T
T
S
N
S
E
S
I
H
Q
Site 28
S212
I
T
L
T
T
S
N
S
E
S
I
H
Q
S
L
Site 29
S214
L
T
T
S
N
S
E
S
I
H
Q
S
L
E
T
Site 30
S218
N
S
E
S
I
H
Q
S
L
E
T
Q
E
V
L
Site 31
S230
E
V
L
E
V
T
T
S
H
L
A
N
P
N
F
Site 32
S239
L
A
N
P
N
F
T
S
N
S
M
E
I
K
S
Site 33
S241
N
P
N
F
T
S
N
S
M
E
I
K
S
A
Q
Site 34
S246
S
N
S
M
E
I
K
S
A
Q
E
N
P
F
L
Site 35
T260
L
F
S
T
I
N
Q
T
V
E
E
L
N
T
N
Site 36
T266
Q
T
V
E
E
L
N
T
N
K
E
S
V
I
A
Site 37
S281
I
F
V
P
A
E
N
S
K
P
S
V
N
S
F
Site 38
S284
P
A
E
N
S
K
P
S
V
N
S
F
I
S
A
Site 39
S287
N
S
K
P
S
V
N
S
F
I
S
A
Q
K
E
Site 40
T301
E
T
T
E
M
E
D
T
D
I
E
D
S
L
Y
Site 41
S306
E
D
T
D
I
E
D
S
L
Y
K
D
V
D
Y
Site 42
Y308
T
D
I
E
D
S
L
Y
K
D
V
D
Y
G
T
Site 43
Y313
S
L
Y
K
D
V
D
Y
G
T
E
V
L
Q
I
Site 44
T315
Y
K
D
V
D
Y
G
T
E
V
L
Q
I
E
H
Site 45
Y324
V
L
Q
I
E
H
S
Y
C
R
Q
D
I
N
K
Site 46
S339
E
H
L
W
Q
K
V
S
K
L
H
S
K
I
T
Site 47
S343
Q
K
V
S
K
L
H
S
K
I
T
L
L
E
L
Site 48
T355
L
E
L
K
E
Q
Q
T
L
G
R
L
K
S
L
Site 49
S361
Q
T
L
G
R
L
K
S
L
E
A
L
I
R
Q
Site 50
S376
L
K
Q
E
N
W
L
S
E
E
N
V
K
I
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation