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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRRT2
Full Name:
Proline-rich transmembrane protein 2
Alias:
DKFZp547J199; Flj25513; IFITMD1; Interferon induced transmembrane protein domain containing 1
Type:
Mass (Da):
34940
Number AA:
340
UniProt ID:
Q7Z6L0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0009607
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
S
S
S
E
I
S
E
M
K
G
Site 2
S9
A
A
S
S
S
E
I
S
E
M
K
G
V
E
E
Site 3
S17
E
M
K
G
V
E
E
S
P
K
V
P
G
E
G
Site 4
S28
P
G
E
G
P
G
H
S
E
A
E
T
G
P
P
Site 5
T32
P
G
H
S
E
A
E
T
G
P
P
Q
V
L
A
Site 6
T55
P
Q
P
G
P
N
T
T
A
A
P
V
D
S
G
Site 7
T72
A
G
L
A
P
E
T
T
E
T
P
A
G
A
S
Site 8
T74
L
A
P
E
T
T
E
T
P
A
G
A
S
E
T
Site 9
S88
T
A
Q
A
T
D
L
S
L
S
P
G
G
E
S
Site 10
S90
Q
A
T
D
L
S
L
S
P
G
G
E
S
K
A
Site 11
S95
S
L
S
P
G
G
E
S
K
A
N
C
S
P
E
Site 12
S100
G
E
S
K
A
N
C
S
P
E
D
P
C
Q
E
Site 13
T108
P
E
D
P
C
Q
E
T
V
S
K
P
E
V
S
Site 14
T119
P
E
V
S
K
E
A
T
A
D
Q
G
S
R
L
Site 15
S124
E
A
T
A
D
Q
G
S
R
L
E
S
A
A
P
Site 16
S128
D
Q
G
S
R
L
E
S
A
A
P
P
E
P
A
Site 17
S148
Q
P
D
P
R
P
D
S
Q
P
T
P
K
P
A
Site 18
T151
P
R
P
D
S
Q
P
T
P
K
P
A
L
Q
P
Site 19
T167
L
P
T
Q
E
D
P
T
P
E
I
L
S
E
S
Site 20
S172
D
P
T
P
E
I
L
S
E
S
V
G
E
K
Q
Site 21
S174
T
P
E
I
L
S
E
S
V
G
E
K
Q
E
N
Site 22
S202
G
P
A
P
E
P
H
S
P
P
S
K
K
S
P
Site 23
S205
P
E
P
H
S
P
P
S
K
K
S
P
P
A
N
Site 24
S208
H
S
P
P
S
K
K
S
P
P
A
N
G
A
P
Site 25
S233
D
R
M
R
R
A
H
S
G
H
P
G
S
P
R
Site 26
S238
A
H
S
G
H
P
G
S
P
R
G
S
L
S
R
Site 27
S242
H
P
G
S
P
R
G
S
L
S
R
H
P
S
S
Site 28
S244
G
S
P
R
G
S
L
S
R
H
P
S
S
Q
L
Site 29
S248
G
S
L
S
R
H
P
S
S
Q
L
A
G
P
G
Site 30
S249
S
L
S
R
H
P
S
S
Q
L
A
G
P
G
V
Site 31
S294
A
F
A
Y
A
V
M
S
R
N
S
L
Q
Q
G
Site 32
S297
Y
A
V
M
S
R
N
S
L
Q
Q
G
D
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation