PhosphoNET

           
Protein Info 
   
Short Name:  K77
Full Name:  Keratin, type II cytoskeletal 1b
Alias:  Cytokeratin-1B; K2C1B; Keratin 77; Keratin-77; KRT1B
Type: 
Mass (Da):  61670
Number AA:  576
UniProt ID:  Q7Z794
International Prot ID:  IPI00376379
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0045095     Uniprot OncoNet
Molecular Function:  GO:0005198     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSHQFSSQSAFSS
Site 2S7_MSHQFSSQSAFSSM
Site 3S9SHQFSSQSAFSSMSR
Site 4S12FSSQSAFSSMSRRVY
Site 5S13SSQSAFSSMSRRVYS
Site 6S15QSAFSSMSRRVYSTS
Site 7Y19SSMSRRVYSTSSSAG
Site 8S20SMSRRVYSTSSSAGS
Site 9T21MSRRVYSTSSSAGSG
Site 10S22SRRVYSTSSSAGSGG
Site 11S23RRVYSTSSSAGSGGG
Site 12S24RVYSTSSSAGSGGGS
Site 13S27STSSSAGSGGGSPAV
Site 14S36GGSPAVGSVCYARGR
Site 15Y49GRCGGGGYGIHGRGF
Site 16S58IHGRGFGSRSLYNLG
Site 17S60GRGFGSRSLYNLGGS
Site 18Y62GFGSRSLYNLGGSRS
Site 19S67SLYNLGGSRSISINL
Site 20S69YNLGGSRSISINLMG
Site 21S71LGGSRSISINLMGRS
Site 22S78SINLMGRSTSGFCQG
Site 23T79INLMGRSTSGFCQGG
Site 24S80NLMGRSTSGFCQGGG
Site 25T140PGGIQEVTINQSLLE
Site 26T162PEIQRIKTQEREQIM
Site 27S177VLNNKFASFIDKVFL
Site 28S229RRQVDLLSAEQMRQN
Site 29Y249MQDVVEDYKSKYEDE
Site 30S251DVVEDYKSKYEDEIN
Site 31Y253VEDYKSKYEDEINKR
Site 32S263EINKRTGSENDFVVL
Site 33Y278KKDVDAAYVSKVDLE
Site 34S280DVDAAYVSKVDLESR
Site 35S286VSKVDLESRVDTLTG
Site 36T290DLESRVDTLTGEVNF
Site 37T292ESRVDTLTGEVNFLK
Site 38T311TELSQVQTHISDTNV
Site 39S321SDTNVILSMDNNRSL
Site 40S327LSMDNNRSLDLDSII
Site 41S332NRSLDLDSIIDAVRT
Site 42Y341IDAVRTQYELIAQRS
Site 43Y356KDEAEALYQTKYQEL
Site 44Y360EALYQTKYQELQITA
Site 45T366KYQELQITAGRHGDD
Site 46T387EIAELNRTVQRLQAE
Site 47S396QRLQAEISNVKKQIE
Site 48S407KQIEQMQSLISDAEE
Site 49Y465LDVEIATYRQLLEGE
Site 50S474QLLEGEESRMSGELQ
Site 51S477EGEESRMSGELQSHV
Site 52S482RMSGELQSHVSISVQ
Site 53S485GELQSHVSISVQNSQ
Site 54S487LQSHVSISVQNSQVS
Site 55S491VSISVQNSQVSVNGG
Site 56S494SVQNSQVSVNGGAGG
Site 57S504GGAGGGGSYGSGGYG
Site 58Y505GAGGGGSYGSGGYGG
Site 59S507GGGGSYGSGGYGGGS
Site 60Y510GSYGSGGYGGGSGGG
Site 61S514SGGYGGGSGGGYGGG
Site 62Y518GGGSGGGYGGGRSYR
Site 63S523GGYGGGRSYRGGGAR
Site 64Y524GYGGGRSYRGGGARG
Site 65S533GGGARGRSGGGYGSG
Site 66Y537RGRSGGGYGSGCGGG
Site 67S539RSGGGYGSGCGGGGS
Site 68S546SGCGGGGSYGGSGRS
Site 69Y547GCGGGGSYGGSGRSG
Site 70S550GGGSYGGSGRSGRGS
Site 71S553SYGGSGRSGRGSSRV
Site 72S557SGRSGRGSSRVQIIQ
Site 73S558GRSGRGSSRVQIIQT
Site 74T565SRVQIIQTSTNTSHR
Site 75S570IQTSTNTSHRRILE_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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