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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBE2Q1
Full Name:
Ubiquitin-conjugating enzyme E2 Q1
Alias:
GTAP; NICE5; NICE-5; PRO3094; Protein NICE-5; UB2Q1; UBE2Q; Ubiquitin carrier protein Q1; Ubiquitin carrier Q1; Ubiquitin-conjugating enzyme E2Q family member 1; Ubiquitin-protein ligase Q1
Type:
EC 6.3.2.19; Ubiquitin ligase; Ligase; Ubiquitin conjugating system
Mass (Da):
46127
Number AA:
422
UniProt ID:
Q7Z7E8
International Prot ID:
IPI00333410
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0043687
GO:0051246
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S50
R
E
L
K
L
L
E
S
I
F
H
R
G
H
E
Site 2
S63
H
E
R
F
R
I
A
S
A
C
L
D
E
L
S
Site 3
S96
P
H
L
P
P
R
G
S
V
P
G
D
P
V
R
Site 4
S120
P
A
V
P
P
I
W
S
V
E
S
D
D
P
N
Site 5
S123
P
P
I
W
S
V
E
S
D
D
P
N
L
A
A
Site 6
S154
Q
H
L
K
R
I
I
S
D
L
C
K
L
Y
N
Site 7
Y160
I
S
D
L
C
K
L
Y
N
L
P
Q
H
P
D
Site 8
S186
Q
C
T
Q
E
D
V
S
S
E
D
E
D
E
E
Site 9
S187
C
T
Q
E
D
V
S
S
E
D
E
D
E
E
M
Site 10
Y204
D
T
E
D
L
D
H
Y
E
M
K
E
E
E
P
Site 11
S217
E
P
A
E
G
K
K
S
E
D
D
G
I
G
K
Site 12
Y241
K
K
N
Q
R
Q
D
Y
L
N
G
A
V
S
G
Site 13
S247
D
Y
L
N
G
A
V
S
G
S
V
Q
A
T
D
Site 14
S249
L
N
G
A
V
S
G
S
V
Q
A
T
D
R
L
Site 15
T253
V
S
G
S
V
Q
A
T
D
R
L
M
K
E
L
Site 16
Y264
M
K
E
L
R
D
I
Y
R
S
Q
S
F
K
G
Site 17
S266
E
L
R
D
I
Y
R
S
Q
S
F
K
G
G
N
Site 18
S268
R
D
I
Y
R
S
Q
S
F
K
G
G
N
Y
A
Site 19
S282
A
V
E
L
V
N
D
S
L
Y
D
W
N
V
K
Site 20
Y284
E
L
V
N
D
S
L
Y
D
W
N
V
K
L
L
Site 21
S297
L
L
K
V
D
Q
D
S
A
L
H
N
D
L
Q
Site 22
S361
L
L
T
K
Q
G
W
S
S
A
Y
S
I
E
S
Site 23
S362
L
T
K
Q
G
W
S
S
A
Y
S
I
E
S
V
Site 24
S365
Q
G
W
S
S
A
Y
S
I
E
S
V
I
M
Q
Site 25
S391
V
Q
F
G
A
N
K
S
Q
Y
S
L
T
R
A
Site 26
Y393
F
G
A
N
K
S
Q
Y
S
L
T
R
A
Q
Q
Site 27
S394
G
A
N
K
S
Q
Y
S
L
T
R
A
Q
Q
S
Site 28
T396
N
K
S
Q
Y
S
L
T
R
A
Q
Q
S
Y
K
Site 29
S401
S
L
T
R
A
Q
Q
S
Y
K
S
L
V
Q
I
Site 30
Y402
L
T
R
A
Q
Q
S
Y
K
S
L
V
Q
I
H
Site 31
S404
R
A
Q
Q
S
Y
K
S
L
V
Q
I
H
E
K
Site 32
Y415
I
H
E
K
N
G
W
Y
T
P
P
K
E
D
G
Site 33
T416
H
E
K
N
G
W
Y
T
P
P
K
E
D
G
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation