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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MIST
Full Name:
Cytokine-dependent hematopoietic cell linker
Alias:
CLNK; Mast cell immunoreceptor signal transducer
Type:
Adaptor/scaffold
Mass (Da):
49554
Number AA:
428
UniProt ID:
Q7Z7G1
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005070
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
R
Q
G
N
R
K
T
T
K
E
G
S
N
D
Site 2
T10
R
Q
G
N
R
K
T
T
K
E
G
S
N
D
L
Site 3
S23
D
L
K
F
Q
N
F
S
L
P
K
N
R
S
W
Site 4
S29
F
S
L
P
K
N
R
S
W
P
R
I
N
S
A
Site 5
S35
R
S
W
P
R
I
N
S
A
T
G
Q
Y
Q
R
Site 6
Y40
I
N
S
A
T
G
Q
Y
Q
R
M
N
K
P
L
Site 7
S65
L
D
G
A
K
G
H
S
D
D
D
Y
D
D
P
Site 8
Y69
K
G
H
S
D
D
D
Y
D
D
P
E
L
R
M
Site 9
S82
R
M
E
E
T
W
Q
S
I
K
I
L
P
A
R
Site 10
S94
P
A
R
P
I
K
E
S
E
Y
A
D
T
H
Y
Site 11
Y96
R
P
I
K
E
S
E
Y
A
D
T
H
Y
F
K
Site 12
T99
K
E
S
E
Y
A
D
T
H
Y
F
K
V
A
M
Site 13
Y101
S
E
Y
A
D
T
H
Y
F
K
V
A
M
D
T
Site 14
T108
Y
F
K
V
A
M
D
T
P
L
P
L
D
T
R
Site 15
T114
D
T
P
L
P
L
D
T
R
T
S
I
S
I
G
Site 16
T116
P
L
P
L
D
T
R
T
S
I
S
I
G
Q
P
Site 17
S117
L
P
L
D
T
R
T
S
I
S
I
G
Q
P
T
Site 18
T127
I
G
Q
P
T
W
N
T
Q
T
R
L
E
R
V
Site 19
S139
E
R
V
D
K
P
I
S
K
D
V
R
S
Q
N
Site 20
S144
P
I
S
K
D
V
R
S
Q
N
I
K
G
D
A
Site 21
S152
Q
N
I
K
G
D
A
S
V
R
K
N
K
I
P
Site 22
T168
P
P
P
R
P
L
I
T
L
P
K
K
Y
Q
P
Site 23
Y173
L
I
T
L
P
K
K
Y
Q
P
L
P
P
E
P
Site 24
S182
P
L
P
P
E
P
E
S
S
R
P
P
L
S
Q
Site 25
S183
L
P
P
E
P
E
S
S
R
P
P
L
S
Q
R
Site 26
S188
E
S
S
R
P
P
L
S
Q
R
H
T
F
P
E
Site 27
T192
P
P
L
S
Q
R
H
T
F
P
E
V
Q
R
M
Site 28
S201
P
E
V
Q
R
M
P
S
Q
I
S
L
R
D
L
Site 29
S204
Q
R
M
P
S
Q
I
S
L
R
D
L
S
E
V
Site 30
S209
Q
I
S
L
R
D
L
S
E
V
L
E
A
E
K
Site 31
T227
N
Q
R
K
P
E
S
T
H
L
L
E
N
Q
N
Site 32
T235
H
L
L
E
N
Q
N
T
Q
E
I
P
L
A
I
Site 33
S243
Q
E
I
P
L
A
I
S
S
S
S
F
T
T
S
Site 34
S244
E
I
P
L
A
I
S
S
S
S
F
T
T
S
N
Site 35
S245
I
P
L
A
I
S
S
S
S
F
T
T
S
N
H
Site 36
S246
P
L
A
I
S
S
S
S
F
T
T
S
N
H
S
Site 37
T248
A
I
S
S
S
S
F
T
T
S
N
H
S
V
Q
Site 38
T249
I
S
S
S
S
F
T
T
S
N
H
S
V
Q
N
Site 39
S250
S
S
S
S
F
T
T
S
N
H
S
V
Q
N
R
Site 40
S253
S
F
T
T
S
N
H
S
V
Q
N
R
D
H
R
Site 41
S267
R
G
G
M
Q
P
C
S
P
Q
R
C
Q
P
P
Site 42
S276
Q
R
C
Q
P
P
A
S
C
S
P
H
E
N
I
Site 43
S278
C
Q
P
P
A
S
C
S
P
H
E
N
I
L
P
Site 44
Y286
P
H
E
N
I
L
P
Y
K
Y
T
S
W
R
P
Site 45
Y288
E
N
I
L
P
Y
K
Y
T
S
W
R
P
P
F
Site 46
T289
N
I
L
P
Y
K
Y
T
S
W
R
P
P
F
P
Site 47
S299
R
P
P
F
P
K
R
S
D
R
K
D
V
Q
H
Site 48
S331
M
K
E
N
K
D
G
S
F
L
V
R
D
C
S
Site 49
S338
S
F
L
V
R
D
C
S
T
K
S
K
E
E
P
Site 50
T339
F
L
V
R
D
C
S
T
K
S
K
E
E
P
Y
Site 51
S341
V
R
D
C
S
T
K
S
K
E
E
P
Y
V
L
Site 52
Y346
T
K
S
K
E
E
P
Y
V
L
A
V
F
Y
E
Site 53
Y352
P
Y
V
L
A
V
F
Y
E
N
K
V
Y
N
V
Site 54
Y357
V
F
Y
E
N
K
V
Y
N
V
K
I
R
F
L
Site 55
S384
R
G
D
E
K
F
D
S
V
E
D
I
I
E
H
Site 56
T406
L
I
D
G
K
D
K
T
G
V
H
R
K
Q
C
Site 57
T416
H
R
K
Q
C
H
L
T
Q
P
L
P
L
T
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation