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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRR6
Full Name:
Centromere protein V
Alias:
CENP-V; Centromere protein V; Nuclear protein p30; P30
Type:
Mass (Da):
29946
Number AA:
275
UniProt ID:
Q7Z7K6
International Prot ID:
IPI00761082
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000777
GO:0005634
GO:0051233
Uniprot
OncoNet
Molecular Function:
GO:0016846
GO:0016829
GO:0016846
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0031508
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
R
R
S
R
S
S
A
A
A
K
L
R
Site 2
S7
_
M
R
R
S
R
S
S
A
A
A
K
L
R
G
Site 3
S18
K
L
R
G
Q
K
R
S
G
A
S
G
A
S
A
Site 4
S21
G
Q
K
R
S
G
A
S
G
A
S
A
A
P
A
Site 5
S24
R
S
G
A
S
G
A
S
A
A
P
A
A
S
A
Site 6
S30
A
S
A
A
P
A
A
S
A
A
A
A
L
A
P
Site 7
S38
A
A
A
A
L
A
P
S
A
T
R
T
R
R
S
Site 8
T40
A
A
L
A
P
S
A
T
R
T
R
R
S
A
S
Site 9
T42
L
A
P
S
A
T
R
T
R
R
S
A
S
Q
A
Site 10
S45
S
A
T
R
T
R
R
S
A
S
Q
A
G
S
K
Site 11
S47
T
R
T
R
R
S
A
S
Q
A
G
S
K
S
Q
Site 12
S51
R
S
A
S
Q
A
G
S
K
S
Q
A
V
E
K
Site 13
S53
A
S
Q
A
G
S
K
S
Q
A
V
E
K
P
P
Site 14
S61
Q
A
V
E
K
P
P
S
E
K
P
R
L
R
R
Site 15
S69
E
K
P
R
L
R
R
S
S
P
R
A
Q
E
E
Site 16
S70
K
P
R
L
R
R
S
S
P
R
A
Q
E
E
G
Site 17
T98
P
P
P
P
P
P
P
T
P
A
T
P
T
S
S
Site 18
T101
P
P
P
P
T
P
A
T
P
T
S
S
A
S
N
Site 19
T103
P
P
T
P
A
T
P
T
S
S
A
S
N
L
D
Site 20
S104
P
T
P
A
T
P
T
S
S
A
S
N
L
D
L
Site 21
S105
T
P
A
T
P
T
S
S
A
S
N
L
D
L
G
Site 22
S107
A
T
P
T
S
S
A
S
N
L
D
L
G
E
Q
Site 23
T120
E
Q
R
E
R
W
E
T
F
Q
K
R
Q
K
L
Site 24
T128
F
Q
K
R
Q
K
L
T
S
E
G
A
A
K
L
Site 25
S129
Q
K
R
Q
K
L
T
S
E
G
A
A
K
L
L
Site 26
S190
R
H
F
I
V
P
A
S
R
F
K
L
L
K
G
Site 27
T203
K
G
A
E
H
I
T
T
Y
T
F
N
T
H
K
Site 28
T205
A
E
H
I
T
T
Y
T
F
N
T
H
K
A
Q
Site 29
T214
N
T
H
K
A
Q
H
T
F
C
K
R
C
G
V
Site 30
Y225
R
C
G
V
Q
S
F
Y
T
P
R
S
N
P
G
Site 31
T226
C
G
V
Q
S
F
Y
T
P
R
S
N
P
G
G
Site 32
S229
Q
S
F
Y
T
P
R
S
N
P
G
G
F
G
I
Site 33
T245
P
H
C
L
D
E
G
T
V
R
S
M
V
T
E
Site 34
S248
L
D
E
G
T
V
R
S
M
V
T
E
E
F
N
Site 35
S257
V
T
E
E
F
N
G
S
D
W
E
K
A
M
K
Site 36
T268
K
A
M
K
E
H
K
T
I
K
N
M
S
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation