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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZER1
Full Name:
Protein zer-1 homolog
Alias:
Hzyg;Zyg-11 homolog B-like protein
Type:
Mass (Da):
88169
Number AA:
766
UniProt ID:
Q7Z7L7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
C
L
R
N
L
D
G
T
L
G
Y
L
L
D
K
Site 2
T33
G
Y
L
L
D
K
E
T
L
R
L
H
P
D
I
Site 3
S69
C
N
F
E
P
H
E
S
F
F
S
L
F
S
D
Site 4
S72
E
P
H
E
S
F
F
S
L
F
S
D
P
R
S
Site 5
S75
E
S
F
F
S
L
F
S
D
P
R
S
T
R
L
Site 6
S79
S
L
F
S
D
P
R
S
T
R
L
T
R
I
H
Site 7
T80
L
F
S
D
P
R
S
T
R
L
T
R
I
H
L
Site 8
T83
D
P
R
S
T
R
L
T
R
I
H
L
R
E
D
Site 9
Y109
K
Q
D
L
V
E
L
Y
L
T
N
C
E
K
L
Site 10
S117
L
T
N
C
E
K
L
S
A
K
S
L
Q
T
L
Site 11
S120
C
E
K
L
S
A
K
S
L
Q
T
L
R
S
F
Site 12
T123
L
S
A
K
S
L
Q
T
L
R
S
F
S
H
T
Site 13
S126
K
S
L
Q
T
L
R
S
F
S
H
T
L
V
S
Site 14
Y144
F
G
C
T
N
I
F
Y
E
E
E
N
P
G
G
Site 15
Y156
P
G
G
C
E
D
E
Y
L
V
N
P
T
C
Q
Site 16
S175
D
F
T
F
E
G
F
S
R
L
R
F
L
N
L
Site 17
S212
D
L
S
G
I
Q
T
S
D
A
A
F
L
T
Q
Site 18
T218
T
S
D
A
A
F
L
T
Q
W
K
D
S
L
V
Site 19
Y230
S
L
V
S
L
V
L
Y
N
M
D
L
S
D
D
Site 20
S254
K
L
R
H
L
D
I
S
R
D
R
L
S
S
Y
Site 21
S259
D
I
S
R
D
R
L
S
S
Y
Y
K
F
K
L
Site 22
S260
I
S
R
D
R
L
S
S
Y
Y
K
F
K
L
T
Site 23
Y261
S
R
D
R
L
S
S
Y
Y
K
F
K
L
T
R
Site 24
Y262
R
D
R
L
S
S
Y
Y
K
F
K
L
T
R
E
Site 25
T267
S
Y
Y
K
F
K
L
T
R
E
V
L
S
L
F
Site 26
S283
Q
K
L
G
N
L
M
S
L
D
I
S
G
H
M
Site 27
T307
M
E
E
E
A
G
Q
T
S
I
E
P
S
K
S
Site 28
S308
E
E
E
A
G
Q
T
S
I
E
P
S
K
S
S
Site 29
S312
G
Q
T
S
I
E
P
S
K
S
S
I
I
P
F
Site 30
S314
T
S
I
E
P
S
K
S
S
I
I
P
F
R
A
Site 31
S315
S
I
E
P
S
K
S
S
I
I
P
F
R
A
L
Site 32
T340
E
N
S
L
C
R
L
T
H
I
P
A
Y
K
V
Site 33
Y345
R
L
T
H
I
P
A
Y
K
V
S
G
D
K
N
Site 34
S372
E
H
R
P
E
I
T
S
R
A
I
N
L
L
F
Site 35
Y406
T
A
L
K
C
H
K
Y
D
R
N
I
Q
V
T
Site 36
T413
Y
D
R
N
I
Q
V
T
G
S
A
A
L
F
Y
Site 37
Y420
T
G
S
A
A
L
F
Y
L
T
N
S
E
Y
R
Site 38
T422
S
A
A
L
F
Y
L
T
N
S
E
Y
R
S
E
Site 39
S424
A
L
F
Y
L
T
N
S
E
Y
R
S
E
Q
S
Site 40
Y426
F
Y
L
T
N
S
E
Y
R
S
E
Q
S
V
K
Site 41
S428
L
T
N
S
E
Y
R
S
E
Q
S
V
K
L
R
Site 42
Y475
P
E
E
L
E
F
Q
Y
R
R
V
N
E
L
L
Site 43
S484
R
V
N
E
L
L
L
S
I
L
N
P
T
R
Q
Site 44
T539
Q
K
K
L
L
D
K
T
C
D
Q
V
M
E
F
Site 45
Y680
N
S
R
R
N
I
N
Y
R
S
F
E
P
I
L
Site 46
S682
R
R
N
I
N
Y
R
S
F
E
P
I
L
R
L
Site 47
S695
R
L
L
P
Q
G
I
S
P
V
S
Q
H
W
A
Site 48
Y717
V
S
V
Y
P
D
K
Y
C
P
L
L
I
K
E
Site 49
T743
M
A
T
A
R
Q
E
T
K
E
M
A
R
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation