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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Kaiso
Full Name:
Transcriptional regulator Kaiso
Alias:
DKFZp686L0369; Zinc finger and BTB domain-containing protein 33
Type:
Intracellular, Plasma membrane, Nucleolus, Cytoplasm, Nucleus protein
Mass (Da):
74484
Number AA:
672
UniProt ID:
Q86T24
International Prot ID:
IPI00465140
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0007242
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
S
R
K
L
I
S
A
T
D
I
Q
Y
S
G
S
Site 2
Y14
I
S
A
T
D
I
Q
Y
S
G
S
L
L
N
S
Site 3
S15
S
A
T
D
I
Q
Y
S
G
S
L
L
N
S
L
Site 4
S17
T
D
I
Q
Y
S
G
S
L
L
N
S
L
N
E
Site 5
S21
Y
S
G
S
L
L
N
S
L
N
E
Q
R
G
H
Site 6
S51
R
A
H
K
N
I
L
S
A
S
S
T
Y
F
H
Site 7
S53
H
K
N
I
L
S
A
S
S
T
Y
F
H
Q
L
Site 8
S87
E
I
L
N
Y
I
Y
S
S
K
I
V
R
V
R
Site 9
S125
V
P
L
S
Q
V
K
S
I
S
G
T
A
Q
D
Site 10
T129
Q
V
K
S
I
S
G
T
A
Q
D
G
N
T
E
Site 11
T135
G
T
A
Q
D
G
N
T
E
P
L
P
P
D
S
Site 12
S142
T
E
P
L
P
P
D
S
G
D
K
N
L
V
I
Site 13
S152
K
N
L
V
I
Q
K
S
K
D
E
A
Q
D
N
Site 14
S172
P
I
I
T
E
S
F
S
L
S
A
E
D
Y
E
Site 15
S174
I
T
E
S
F
S
L
S
A
E
D
Y
E
M
K
Site 16
T186
E
M
K
K
I
I
V
T
D
S
D
D
D
D
D
Site 17
S188
K
K
I
I
V
T
D
S
D
D
D
D
D
D
V
Site 18
T204
F
C
S
E
I
L
P
T
K
E
T
L
P
S
N
Site 19
S210
P
T
K
E
T
L
P
S
N
N
T
V
A
Q
V
Site 20
T213
E
T
L
P
S
N
N
T
V
A
Q
V
Q
S
N
Site 21
S232
A
I
S
D
V
A
P
S
A
S
N
N
S
P
P
Site 22
S234
S
D
V
A
P
S
A
S
N
N
S
P
P
L
T
Site 23
S237
A
P
S
A
S
N
N
S
P
P
L
T
N
I
T
Site 24
T241
S
N
N
S
P
P
L
T
N
I
T
P
T
Q
K
Site 25
T244
S
P
P
L
T
N
I
T
P
T
Q
K
L
P
T
Site 26
T251
T
P
T
Q
K
L
P
T
P
V
N
Q
A
T
L
Site 27
T257
P
T
P
V
N
Q
A
T
L
S
Q
T
Q
G
S
Site 28
S259
P
V
N
Q
A
T
L
S
Q
T
Q
G
S
E
K
Site 29
T286
N
I
I
L
L
N
Q
T
P
L
S
T
P
P
N
Site 30
S289
L
L
N
Q
T
P
L
S
T
P
P
N
V
S
S
Site 31
T290
L
N
Q
T
P
L
S
T
P
P
N
V
S
S
S
Site 32
S295
L
S
T
P
P
N
V
S
S
S
L
P
N
H
M
Site 33
S296
S
T
P
P
N
V
S
S
S
L
P
N
H
M
P
Site 34
S297
T
P
P
N
V
S
S
S
L
P
N
H
M
P
S
Site 35
S304
S
L
P
N
H
M
P
S
S
I
N
L
L
V
Q
Site 36
S305
L
P
N
H
M
P
S
S
I
N
L
L
V
Q
N
Site 37
T315
L
L
V
Q
N
Q
Q
T
P
N
S
A
I
L
T
Site 38
S318
Q
N
Q
Q
T
P
N
S
A
I
L
T
G
N
K
Site 39
T322
T
P
N
S
A
I
L
T
G
N
K
A
N
E
E
Site 40
T341
I
I
D
D
D
D
D
T
I
S
S
S
P
D
S
Site 41
S343
D
D
D
D
D
T
I
S
S
S
P
D
S
A
V
Site 42
S344
D
D
D
D
T
I
S
S
S
P
D
S
A
V
S
Site 43
S345
D
D
D
T
I
S
S
S
P
D
S
A
V
S
N
Site 44
S348
T
I
S
S
S
P
D
S
A
V
S
N
T
S
L
Site 45
S351
S
S
P
D
S
A
V
S
N
T
S
L
V
P
Q
Site 46
S354
D
S
A
V
S
N
T
S
L
V
P
Q
A
D
T
Site 47
T361
S
L
V
P
Q
A
D
T
S
Q
N
T
S
F
D
Site 48
S362
L
V
P
Q
A
D
T
S
Q
N
T
S
F
D
G
Site 49
S366
A
D
T
S
Q
N
T
S
F
D
G
S
L
I
Q
Site 50
S370
Q
N
T
S
F
D
G
S
L
I
Q
K
M
Q
I
Site 51
S386
T
L
L
Q
E
P
L
S
N
S
L
K
I
S
D
Site 52
S392
L
S
N
S
L
K
I
S
D
I
I
T
R
N
T
Site 53
T396
L
K
I
S
D
I
I
T
R
N
T
N
D
P
G
Site 54
T399
S
D
I
I
T
R
N
T
N
D
P
G
V
G
S
Site 55
S428
A
T
E
I
E
G
L
S
T
G
C
K
V
Y
A
Site 56
T429
T
E
I
E
G
L
S
T
G
C
K
V
Y
A
N
Site 57
Y434
L
S
T
G
C
K
V
Y
A
N
I
G
E
D
T
Site 58
T441
Y
A
N
I
G
E
D
T
Y
D
I
V
I
P
V
Site 59
Y442
A
N
I
G
E
D
T
Y
D
I
V
I
P
V
K
Site 60
T466
L
E
N
E
I
P
K
T
S
G
S
E
M
A
N
Site 61
S469
E
I
P
K
T
S
G
S
E
M
A
N
K
R
M
Site 62
Y484
K
V
K
H
D
D
H
Y
E
L
I
V
D
G
R
Site 63
T507
K
R
S
Y
V
C
L
T
S
L
R
R
H
F
N
Site 64
Y522
I
H
S
W
E
K
K
Y
P
C
R
Y
C
E
K
Site 65
Y526
E
K
K
Y
P
C
R
Y
C
E
K
V
F
P
L
Site 66
T545
T
K
H
E
I
H
H
T
G
E
R
R
Y
Q
C
Site 67
Y550
H
H
T
G
E
R
R
Y
Q
C
L
A
C
G
K
Site 68
S558
Q
C
L
A
C
G
K
S
F
I
N
Y
Q
F
M
Site 69
Y562
C
G
K
S
F
I
N
Y
Q
F
M
S
S
H
I
Site 70
S567
I
N
Y
Q
F
M
S
S
H
I
K
S
V
H
S
Site 71
S571
F
M
S
S
H
I
K
S
V
H
S
Q
D
P
S
Site 72
S574
S
H
I
K
S
V
H
S
Q
D
P
S
G
D
S
Site 73
S578
S
V
H
S
Q
D
P
S
G
D
S
K
L
Y
R
Site 74
S581
S
Q
D
P
S
G
D
S
K
L
Y
R
L
H
P
Site 75
Y597
R
S
L
Q
I
R
Q
Y
A
Y
L
S
D
R
S
Site 76
Y599
L
Q
I
R
Q
Y
A
Y
L
S
D
R
S
S
T
Site 77
S601
I
R
Q
Y
A
Y
L
S
D
R
S
S
T
I
P
Site 78
S605
A
Y
L
S
D
R
S
S
T
I
P
A
M
K
D
Site 79
T606
Y
L
S
D
R
S
S
T
I
P
A
M
K
D
D
Site 80
Y617
M
K
D
D
G
I
G
Y
K
V
D
T
G
K
E
Site 81
T621
G
I
G
Y
K
V
D
T
G
K
E
P
P
V
G
Site 82
S632
P
P
V
G
T
T
T
S
T
Q
N
K
P
M
T
Site 83
T639
S
T
Q
N
K
P
M
T
W
E
D
I
F
I
Q
Site 84
S661
K
Q
N
V
T
D
G
S
T
E
F
E
F
I
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation