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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PATL1
Full Name:
Protein PAT1 homolog 1
Alias:
DKFZp451I053; FLJ36874; protein associated with topoisomerase II 1
Type:
Unknown function
Mass (Da):
86850
Number AA:
770
UniProt ID:
Q86TB9
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000932
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T36
I
D
Q
F
N
D
D
T
F
G
S
G
A
V
D
Site 2
S91
E
N
L
A
E
R
L
S
K
M
V
I
E
N
E
Site 3
S120
V
L
Q
P
Q
P
G
S
L
N
S
S
I
W
D
Site 4
S124
Q
P
G
S
L
N
S
S
I
W
D
G
S
E
V
Site 5
S129
N
S
S
I
W
D
G
S
E
V
L
R
R
I
R
Site 6
Y152
P
T
V
S
V
L
E
Y
A
L
P
Q
R
P
P
Site 7
S169
P
E
D
D
R
D
L
S
E
R
A
L
P
R
R
Site 8
S177
E
R
A
L
P
R
R
S
T
S
P
I
I
G
S
Site 9
T178
R
A
L
P
R
R
S
T
S
P
I
I
G
S
P
Site 10
S179
A
L
P
R
R
S
T
S
P
I
I
G
S
P
P
Site 11
S184
S
T
S
P
I
I
G
S
P
P
V
R
A
V
P
Site 12
T194
V
R
A
V
P
I
G
T
P
P
K
Q
M
A
V
Site 13
Y224
R
P
P
M
P
P
R
Y
P
A
P
Y
G
E
R
Site 14
Y228
P
P
R
Y
P
A
P
Y
G
E
R
M
S
P
N
Site 15
S233
A
P
Y
G
E
R
M
S
P
N
Q
L
C
S
V
Site 16
S239
M
S
P
N
Q
L
C
S
V
P
N
S
S
L
L
Site 17
S259
P
S
V
P
P
V
L
S
P
L
Q
R
A
Q
L
Site 18
S278
Q
L
Q
P
G
R
M
S
P
S
Q
F
A
R
V
Site 19
S280
Q
P
G
R
M
S
P
S
Q
F
A
R
V
P
G
Site 20
S320
P
G
F
R
A
F
F
S
A
P
P
S
A
T
P
Site 21
S324
A
F
F
S
A
P
P
S
A
T
P
P
P
Q
Q
Site 22
T326
F
S
A
P
P
S
A
T
P
P
P
Q
Q
H
P
Site 23
S345
P
H
L
Q
N
L
R
S
Q
A
P
M
F
R
P
Site 24
T354
A
P
M
F
R
P
D
T
T
H
L
H
P
Q
H
Site 25
T355
P
M
F
R
P
D
T
T
H
L
H
P
Q
H
R
Site 26
S374
Q
R
Q
Q
Q
N
R
S
Q
H
R
N
L
N
G
Site 27
S387
N
G
A
G
D
R
G
S
H
R
S
S
H
Q
D
Site 28
S390
G
D
R
G
S
H
R
S
S
H
Q
D
H
L
R
Site 29
S391
D
R
G
S
H
R
S
S
H
Q
D
H
L
R
K
Site 30
Y401
D
H
L
R
K
D
P
Y
A
N
L
M
L
Q
R
Site 31
Y427
Q
L
Q
S
T
D
P
Y
L
D
D
F
Y
Y
Q
Site 32
Y432
D
P
Y
L
D
D
F
Y
Y
Q
N
Y
F
E
K
Site 33
Y433
P
Y
L
D
D
F
Y
Y
Q
N
Y
F
E
K
L
Site 34
Y436
D
D
F
Y
Y
Q
N
Y
F
E
K
L
E
K
L
Site 35
T459
D
G
P
K
K
E
R
T
K
L
I
T
P
Q
V
Site 36
T463
K
E
R
T
K
L
I
T
P
Q
V
A
K
L
E
Site 37
Y473
V
A
K
L
E
H
A
Y
K
P
V
Q
F
E
G
Site 38
T486
E
G
S
L
G
K
L
T
V
S
S
V
N
N
P
Site 39
S488
S
L
G
K
L
T
V
S
S
V
N
N
P
R
K
Site 40
S489
L
G
K
L
T
V
S
S
V
N
N
P
R
K
M
Site 41
S505
D
A
V
V
T
S
R
S
E
D
D
E
T
K
E
Site 42
T510
S
R
S
E
D
D
E
T
K
E
K
Q
V
R
D
Site 43
T522
V
R
D
K
R
R
K
T
L
V
I
I
E
K
T
Site 44
Y539
L
L
L
D
V
E
D
Y
E
R
R
Y
L
L
S
Site 45
Y543
V
E
D
Y
E
R
R
Y
L
L
S
L
E
E
E
Site 46
S546
Y
E
R
R
Y
L
L
S
L
E
E
E
R
P
A
Site 47
Y566
K
H
K
I
C
S
M
Y
D
N
L
R
G
K
L
Site 48
S580
L
P
G
Q
E
R
P
S
D
D
H
F
V
Q
I
Site 49
T668
N
L
P
Q
S
A
A
T
P
A
L
S
N
P
H
Site 50
S701
S
R
G
E
D
L
Q
S
S
D
P
A
T
E
S
Site 51
S702
R
G
E
D
L
Q
S
S
D
P
A
T
E
S
T
Site 52
T706
L
Q
S
S
D
P
A
T
E
S
T
Q
N
N
Q
Site 53
Y750
L
V
S
L
F
S
R
Y
V
D
R
Q
K
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation