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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf21
Full Name:
Pumilio domain-containing protein C14orf21
Alias:
Chromosome 14 open reading frame 21; CN021; KIAA2021
Type:
Mass (Da):
69438
Number AA:
636
UniProt ID:
Q86U38
International Prot ID:
IPI00216999
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
Q
G
P
R
S
P
H
K
V
G
R
R
Site 2
S28
R
G
R
G
A
K
G
S
G
R
P
L
P
G
R
Site 3
S47
W
P
P
P
D
G
R
S
E
P
A
P
D
S
H
Site 4
S53
R
S
E
P
A
P
D
S
H
P
H
L
S
P
E
Site 5
S58
P
D
S
H
P
H
L
S
P
E
A
L
G
Y
F
Site 6
S70
G
Y
F
R
R
A
L
S
A
L
K
E
A
P
E
Site 7
T78
A
L
K
E
A
P
E
T
G
E
E
R
D
L
M
Site 8
S101
E
T
Q
A
L
A
L
S
T
N
R
T
G
S
E
Site 9
T102
T
Q
A
L
A
L
S
T
N
R
T
G
S
E
M
Site 10
T105
L
A
L
S
T
N
R
T
G
S
E
M
L
Q
E
Site 11
S107
L
S
T
N
R
T
G
S
E
M
L
Q
E
L
L
Site 12
T135
A
L
R
S
N
L
R
T
V
A
C
H
R
C
G
Site 13
S221
L
G
G
T
I
L
E
S
E
R
A
R
P
R
G
Site 14
S229
E
R
A
R
P
R
G
S
Q
S
S
E
A
Q
K
Site 15
S231
A
R
P
R
G
S
Q
S
S
E
A
Q
K
T
P
Site 16
S232
R
P
R
G
S
Q
S
S
E
A
Q
K
T
P
A
Site 17
T237
Q
S
S
E
A
Q
K
T
P
A
Q
E
C
K
P
Site 18
T252
A
D
F
E
V
P
E
T
F
L
N
R
L
Q
D
Site 19
S261
L
N
R
L
Q
D
L
S
S
S
F
L
K
D
I
Site 20
S262
N
R
L
Q
D
L
S
S
S
F
L
K
D
I
A
Site 21
S308
N
A
V
I
G
Y
L
S
T
R
G
S
S
V
D
Site 22
S312
G
Y
L
S
T
R
G
S
S
V
D
G
S
P
L
Site 23
S313
Y
L
S
T
R
G
S
S
V
D
G
S
P
L
L
Site 24
T327
L
L
F
L
R
D
Q
T
S
S
R
L
L
E
Q
Site 25
S328
L
F
L
R
D
Q
T
S
S
R
L
L
E
Q
V
Site 26
S329
F
L
R
D
Q
T
S
S
R
L
L
E
Q
V
L
Site 27
S346
L
E
P
P
R
L
Q
S
L
F
E
E
H
L
Q
Site 28
T377
Q
R
L
L
D
A
V
T
T
P
E
L
L
S
P
Site 29
S437
F
H
C
A
E
P
S
S
R
Q
V
A
C
V
P
Site 30
S535
D
A
I
L
T
S
P
S
V
T
R
K
L
R
R
Site 31
Y552
L
Q
N
L
K
G
Q
Y
V
A
L
A
C
S
R
Site 32
S570
R
V
L
D
A
I
W
S
G
A
A
L
R
A
R
Site 33
T607
V
A
R
N
V
A
L
T
T
F
L
K
R
R
E
Site 34
T608
A
R
N
V
A
L
T
T
F
L
K
R
R
E
A
Site 35
S632
K
R
R
R
A
L
N
S
I
L
E
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation