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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRPF39
Full Name:
Pre-mRNA-processing factor 39
Alias:
PRP39 homolog
Type:
Mass (Da):
78430
Number AA:
669
UniProt ID:
Q86UA1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
Q
N
S
H
M
D
E
Y
R
N
S
S
N
G
S
Site 2
S12
H
M
D
E
Y
R
N
S
S
N
G
S
T
G
N
Site 3
S13
M
D
E
Y
R
N
S
S
N
G
S
T
G
N
S
Site 4
S16
Y
R
N
S
S
N
G
S
T
G
N
S
S
E
V
Site 5
T17
R
N
S
S
N
G
S
T
G
N
S
S
E
V
V
Site 6
S20
S
N
G
S
T
G
N
S
S
E
V
V
V
E
H
Site 7
S32
V
E
H
P
T
D
F
S
T
E
I
M
N
V
T
Site 8
S44
N
V
T
E
M
E
Q
S
P
D
D
S
P
N
V
Site 9
S48
M
E
Q
S
P
D
D
S
P
N
V
N
A
S
T
Site 10
S54
D
S
P
N
V
N
A
S
T
E
E
T
E
M
A
Site 11
T58
V
N
A
S
T
E
E
T
E
M
A
S
A
V
D
Site 12
T69
S
A
V
D
L
P
V
T
L
T
E
T
E
A
N
Site 13
Y81
E
A
N
F
P
P
E
Y
E
K
F
W
K
T
V
Site 14
T87
E
Y
E
K
F
W
K
T
V
E
N
N
P
Q
D
Site 15
Y104
G
W
V
Y
L
L
Q
Y
V
E
Q
E
N
H
L
Site 16
Y135
C
Y
G
Y
W
K
K
Y
A
D
L
E
K
R
H
Site 17
S148
R
H
D
N
I
K
P
S
D
E
V
Y
R
R
G
Site 18
Y152
I
K
P
S
D
E
V
Y
R
R
G
L
Q
A
I
Site 19
T176
Y
I
N
F
L
K
E
T
L
D
P
G
D
P
E
Site 20
T184
L
D
P
G
D
P
E
T
N
N
T
I
R
G
T
Site 21
T187
G
D
P
E
T
N
N
T
I
R
G
T
F
E
H
Site 22
T191
T
N
N
T
I
R
G
T
F
E
H
A
V
L
A
Site 23
Y212
S
D
R
L
W
E
M
Y
I
N
W
E
N
E
Q
Site 24
T226
Q
G
N
L
R
E
V
T
A
I
Y
D
R
I
L
Site 25
T237
D
R
I
L
G
I
P
T
Q
L
Y
S
H
H
F
Site 26
Y240
L
G
I
P
T
Q
L
Y
S
H
H
F
Q
R
F
Site 27
T261
N
L
P
R
D
L
L
T
G
E
Q
F
I
Q
L
Site 28
S274
Q
L
R
R
E
L
A
S
V
N
G
H
S
G
D
Site 29
S279
L
A
S
V
N
G
H
S
G
D
D
G
P
P
G
Site 30
S291
P
P
G
D
D
L
P
S
G
I
E
D
I
T
D
Site 31
T297
P
S
G
I
E
D
I
T
D
P
A
K
L
I
T
Site 32
Y323
I
H
Q
E
M
F
N
Y
N
E
H
E
V
S
K
Site 33
T333
H
E
V
S
K
R
W
T
F
E
E
G
I
K
R
Site 34
Y342
E
E
G
I
K
R
P
Y
F
H
V
K
P
L
E
Site 35
Y359
Q
L
K
N
W
K
E
Y
L
E
F
E
I
E
N
Site 36
T368
E
F
E
I
E
N
G
T
H
E
R
V
V
V
L
Site 37
S401
A
K
Y
M
E
N
H
S
I
E
G
V
R
H
V
Site 38
T414
H
V
F
S
R
A
C
T
I
H
L
P
K
K
P
Site 39
T446
E
A
R
N
I
L
K
T
F
E
E
C
V
L
G
Site 40
S463
M
V
R
L
R
R
V
S
L
E
R
R
H
G
N
Site 41
S487
D
A
I
K
N
A
K
S
N
N
E
S
S
F
Y
Site 42
S491
N
A
K
S
N
N
E
S
S
F
Y
A
V
K
L
Site 43
S492
A
K
S
N
N
E
S
S
F
Y
A
V
K
L
A
Site 44
Y494
S
N
N
E
S
S
F
Y
A
V
K
L
A
R
H
Site 45
S512
I
Q
K
N
L
P
K
S
R
K
V
L
L
E
A
Site 46
Y530
D
K
E
N
T
K
L
Y
L
N
L
L
E
M
E
Site 47
S539
N
L
L
E
M
E
Y
S
G
D
L
K
Q
N
E
Site 48
S560
F
D
K
A
V
H
G
S
L
P
I
K
M
R
I
Site 49
T568
L
P
I
K
M
R
I
T
F
S
Q
R
K
V
E
Site 50
S570
I
K
M
R
I
T
F
S
Q
R
K
V
E
F
L
Site 51
S582
E
F
L
E
D
F
G
S
D
V
N
K
L
L
N
Site 52
S603
T
L
L
K
E
Q
D
S
L
K
R
K
A
E
N
Site 53
S612
K
R
K
A
E
N
G
S
E
E
P
E
E
K
K
Site 54
T625
K
K
A
H
T
E
D
T
T
S
S
S
T
Q
M
Site 55
S627
A
H
T
E
D
T
T
S
S
S
T
Q
M
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation