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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCA12
Full Name:
ATP-binding cassette sub-family A member 12
Alias:
ABC12; ABCAC; ATP-binding cassette 12; ATP-binding cassette transporter 12; ATP-binding cassette, sub-family A (ABC1) member 12; ATP-binding cassette, sub-family A (ABC1), member 12; ATP-binding cassette, sub-family A, member 12; DKFZP434G232; Ichthyosis congenita II, lamellar ichthyosis B; ICR2B; LI2
Type:
Transporter
Mass (Da):
293251
Number AA:
2595
UniProt ID:
Q86UK0
International Prot ID:
IPI00457109
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
PhosphoSite+
KinaseNET
Biological Process:
GO:0019725
GO:0006869
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T50
T
R
T
K
F
P
P
T
A
K
P
T
C
Y
L
Site 2
Y56
P
T
A
K
P
T
C
Y
L
A
P
R
N
L
P
Site 3
T65
A
P
R
N
L
P
S
T
G
F
F
P
F
L
Q
Site 4
S80
T
L
L
C
D
T
D
S
K
C
K
D
T
P
Y
Site 5
T85
T
D
S
K
C
K
D
T
P
Y
G
P
Q
D
L
Site 6
Y87
S
K
C
K
D
T
P
Y
G
P
Q
D
L
L
R
Site 7
S112
D
S
E
I
L
R
K
S
S
N
L
D
K
D
S
Site 8
S113
S
E
I
L
R
K
S
S
N
L
D
K
D
S
S
Site 9
S119
S
S
N
L
D
K
D
S
S
L
S
F
Q
S
T
Site 10
S120
S
N
L
D
K
D
S
S
L
S
F
Q
S
T
Q
Site 11
S122
L
D
K
D
S
S
L
S
F
Q
S
T
Q
V
P
Site 12
T126
S
S
L
S
F
Q
S
T
Q
V
P
E
R
R
H
Site 13
S135
V
P
E
R
R
H
A
S
L
A
T
V
F
P
S
Site 14
T138
R
R
H
A
S
L
A
T
V
F
P
S
P
S
S
Site 15
S144
A
T
V
F
P
S
P
S
S
D
L
E
I
P
G
Site 16
S145
T
V
F
P
S
P
S
S
D
L
E
I
P
G
T
Site 17
T152
S
D
L
E
I
P
G
T
Y
T
F
N
G
S
Q
Site 18
S175
E
K
L
L
K
Q
N
S
T
S
E
D
I
R
R
Site 19
S177
L
L
K
Q
N
S
T
S
E
D
I
R
R
E
L
Site 20
S187
I
R
R
E
L
C
D
S
Y
S
G
Y
I
V
D
Site 21
Y188
R
R
E
L
C
D
S
Y
S
G
Y
I
V
D
D
Site 22
S189
R
E
L
C
D
S
Y
S
G
Y
I
V
D
D
A
Site 23
S230
Q
E
L
N
K
Q
F
S
Q
L
S
S
D
P
N
Site 24
S234
K
Q
F
S
Q
L
S
S
D
P
N
N
Q
K
I
Site 25
S251
Q
E
I
V
R
M
L
S
F
F
S
Q
V
Q
E
Site 26
S254
V
R
M
L
S
F
F
S
Q
V
Q
E
Q
K
A
Site 27
T277
P
N
V
F
Q
N
D
T
S
L
S
N
L
F
D
Site 28
S278
N
V
F
Q
N
D
T
S
L
S
N
L
F
D
V
Site 29
S291
D
V
L
R
K
A
N
S
V
L
L
V
V
Q
K
Site 30
T305
K
V
Y
P
R
F
A
T
N
E
G
F
R
T
L
Site 31
T311
A
T
N
E
G
F
R
T
L
Q
K
S
V
K
H
Site 32
S315
G
F
R
T
L
Q
K
S
V
K
H
L
L
Y
T
Site 33
Y321
K
S
V
K
H
L
L
Y
T
L
D
S
P
A
Q
Site 34
T322
S
V
K
H
L
L
Y
T
L
D
S
P
A
Q
G
Site 35
S325
H
L
L
Y
T
L
D
S
P
A
Q
G
D
S
D
Site 36
S331
D
S
P
A
Q
G
D
S
D
N
I
T
H
V
W
Site 37
T345
W
N
E
D
D
G
Q
T
L
S
P
S
S
L
A
Site 38
S347
E
D
D
G
Q
T
L
S
P
S
S
L
A
A
Q
Site 39
S387
C
V
R
N
V
T
D
S
L
A
R
G
S
P
E
Site 40
S392
T
D
S
L
A
R
G
S
P
E
N
L
R
L
L
Site 41
S401
E
N
L
R
L
L
Q
S
T
I
R
F
K
K
S
Site 42
T402
N
L
R
L
L
Q
S
T
I
R
F
K
K
S
F
Site 43
S408
S
T
I
R
F
K
K
S
F
L
R
N
G
S
Y
Site 44
S414
K
S
F
L
R
N
G
S
Y
E
D
Y
F
P
P
Site 45
Y415
S
F
L
R
N
G
S
Y
E
D
Y
F
P
P
V
Site 46
Y418
R
N
G
S
Y
E
D
Y
F
P
P
V
P
E
V
Site 47
S428
P
V
P
E
V
L
K
S
K
L
S
Q
L
R
N
Site 48
S431
E
V
L
K
S
K
L
S
Q
L
R
N
L
T
E
Site 49
T437
L
S
Q
L
R
N
L
T
E
L
L
C
E
S
E
Site 50
T445
E
L
L
C
E
S
E
T
F
S
L
I
E
K
S
Site 51
S447
L
C
E
S
E
T
F
S
L
I
E
K
S
C
Q
Site 52
S452
T
F
S
L
I
E
K
S
C
Q
L
S
D
M
S
Site 53
S456
I
E
K
S
C
Q
L
S
D
M
S
F
G
S
L
Site 54
S459
S
C
Q
L
S
D
M
S
F
G
S
L
C
E
E
Site 55
S462
L
S
D
M
S
F
G
S
L
C
E
E
S
E
F
Site 56
T503
K
K
V
R
D
L
L
T
G
D
P
S
K
I
N
Site 57
S507
D
L
L
T
G
D
P
S
K
I
N
L
N
M
D
Site 58
Y525
E
Q
A
L
Q
M
N
Y
L
E
N
I
T
Q
L
Site 59
S545
A
M
L
H
V
N
N
S
A
D
A
S
E
K
P
Site 60
S549
V
N
N
S
A
D
A
S
E
K
P
G
Q
L
L
Site 61
T572
L
K
E
D
L
R
R
T
T
G
M
S
N
R
T
Site 62
T573
K
E
D
L
R
R
T
T
G
M
S
N
R
T
I
Site 63
S576
L
R
R
T
T
G
M
S
N
R
T
I
D
K
L
Site 64
T611
S
C
D
T
N
I
T
T
P
K
L
E
D
A
M
Site 65
S625
M
K
E
F
C
N
L
S
L
S
E
R
S
R
Q
Site 66
S627
E
F
C
N
L
S
L
S
E
R
S
R
Q
S
Y
Site 67
S633
L
S
E
R
S
R
Q
S
Y
L
I
G
L
T
L
Site 68
Y634
S
E
R
S
R
Q
S
Y
L
I
G
L
T
L
L
Site 69
Y643
I
G
L
T
L
L
H
Y
L
N
I
Y
N
F
T
Site 70
Y651
L
N
I
Y
N
F
T
Y
K
V
F
F
P
R
K
Site 71
S682
E
I
L
N
Q
M
A
S
G
T
H
P
L
L
D
Site 72
S693
P
L
L
D
K
M
R
S
L
K
Q
M
H
L
P
Site 73
S702
K
Q
M
H
L
P
R
S
V
P
L
T
Q
A
M
Site 74
T706
L
P
R
S
V
P
L
T
Q
A
M
Y
R
S
N
Site 75
Y710
V
P
L
T
Q
A
M
Y
R
S
N
R
M
N
T
Site 76
T717
Y
R
S
N
R
M
N
T
P
Q
G
S
F
S
T
Site 77
S721
R
M
N
T
P
Q
G
S
F
S
T
I
S
Q
A
Site 78
S723
N
T
P
Q
G
S
F
S
T
I
S
Q
A
L
C
Site 79
S726
Q
G
S
F
S
T
I
S
Q
A
L
C
S
Q
G
Site 80
S731
T
I
S
Q
A
L
C
S
Q
G
I
T
T
E
Y
Site 81
Y738
S
Q
G
I
T
T
E
Y
L
T
A
M
L
P
S
Site 82
S746
L
T
A
M
L
P
S
S
Q
R
P
K
G
N
H
Site 83
T759
N
H
T
K
D
F
L
T
Y
K
L
T
K
E
Q
Site 84
T763
D
F
L
T
Y
K
L
T
K
E
Q
I
A
S
K
Site 85
S769
L
T
K
E
Q
I
A
S
K
Y
G
I
P
I
N
Site 86
Y771
K
E
Q
I
A
S
K
Y
G
I
P
I
N
T
T
Site 87
Y811
M
L
L
G
R
I
L
Y
A
P
Y
N
P
V
T
Site 88
Y814
G
R
I
L
Y
A
P
Y
N
P
V
T
K
A
I
Site 89
S825
T
K
A
I
M
E
K
S
N
V
T
L
R
Q
L
Site 90
T828
I
M
E
K
S
N
V
T
L
R
Q
L
A
E
L
Site 91
S839
L
A
E
L
R
E
K
S
Q
E
W
M
D
K
S
Site 92
S852
K
S
P
L
F
M
N
S
F
H
L
L
N
Q
A
Site 93
T866
A
I
P
M
L
Q
N
T
L
R
N
P
F
V
Q
Site 94
S916
D
Q
L
N
T
L
S
S
L
T
V
N
I
S
S
Site 95
Y927
N
I
S
S
C
V
L
Y
D
R
I
Q
A
A
K
Site 96
T935
D
R
I
Q
A
A
K
T
I
D
E
M
E
R
E
Site 97
Y947
E
R
E
A
K
R
L
Y
K
S
N
E
L
F
G
Site 98
S949
E
A
K
R
L
Y
K
S
N
E
L
F
G
S
V
Site 99
S955
K
S
N
E
L
F
G
S
V
I
F
K
L
P
S
Site 100
S962
S
V
I
F
K
L
P
S
N
R
S
W
H
R
G
Site 101
S965
F
K
L
P
S
N
R
S
W
H
R
G
Y
D
S
Site 102
Y970
N
R
S
W
H
R
G
Y
D
S
G
N
V
F
L
Site 103
S972
S
W
H
R
G
Y
D
S
G
N
V
F
L
P
P
Site 104
S988
I
K
Y
T
I
R
M
S
L
K
T
A
Q
T
T
Site 105
T991
T
I
R
M
S
L
K
T
A
Q
T
T
R
S
L
Site 106
T994
M
S
L
K
T
A
Q
T
T
R
S
L
R
T
K
Site 107
S997
K
T
A
Q
T
T
R
S
L
R
T
K
I
W
A
Site 108
T1000
Q
T
T
R
S
L
R
T
K
I
W
A
P
G
P
Site 109
S1010
W
A
P
G
P
H
N
S
P
S
H
N
Q
I
Y
Site 110
S1012
P
G
P
H
N
S
P
S
H
N
Q
I
Y
G
R
Site 111
Y1017
S
P
S
H
N
Q
I
Y
G
R
A
F
I
Y
L
Site 112
Y1023
I
Y
G
R
A
F
I
Y
L
Q
D
S
I
E
R
Site 113
T1037
R
A
I
I
E
L
Q
T
G
R
N
S
Q
E
I
Site 114
S1041
E
L
Q
T
G
R
N
S
Q
E
I
A
V
Q
V
Site 115
Y1053
V
Q
V
Q
A
I
P
Y
P
C
F
M
K
D
N
Site 116
T1063
F
M
K
D
N
F
L
T
S
V
S
Y
S
L
P
Site 117
Y1099
K
D
L
R
L
H
E
Y
M
K
M
M
G
V
N
Site 118
S1220
P
T
A
F
S
Y
A
S
Q
Y
I
A
R
Y
E
Site 119
Y1222
A
F
S
Y
A
S
Q
Y
I
A
R
Y
E
E
Q
Site 120
Y1226
A
S
Q
Y
I
A
R
Y
E
E
Q
G
I
G
L
Site 121
Y1239
G
L
Q
W
E
N
M
Y
T
S
P
V
Q
D
D
Site 122
T1247
T
S
P
V
Q
D
D
T
T
S
F
G
W
L
C
Site 123
T1248
S
P
V
Q
D
D
T
T
S
F
G
W
L
C
C
Site 124
Y1279
R
N
V
F
P
G
T
Y
G
M
A
A
P
W
Y
Site 125
Y1293
Y
F
P
I
L
P
S
Y
W
K
E
R
F
G
C
Site 126
S1326
Q
N
T
N
P
S
A
S
P
E
Y
M
F
S
S
Site 127
Y1329
N
P
S
A
S
P
E
Y
M
F
S
S
N
I
E
Site 128
S1332
A
S
P
E
Y
M
F
S
S
N
I
E
P
E
P
Site 129
S1333
S
P
E
Y
M
F
S
S
N
I
E
P
E
P
K
Site 130
T1343
E
P
E
P
K
D
L
T
V
G
V
A
L
H
G
Site 131
Y1369
D
N
L
N
L
N
F
Y
E
G
H
I
T
S
L
Site 132
T1374
N
F
Y
E
G
H
I
T
S
L
L
G
P
N
G
Site 133
S1375
F
Y
E
G
H
I
T
S
L
L
G
P
N
G
A
Site 134
T1385
G
P
N
G
A
G
K
T
T
T
I
S
M
L
T
Site 135
Y1405
S
A
G
T
I
F
V
Y
G
K
D
I
K
T
D
Site 136
T1411
V
Y
G
K
D
I
K
T
D
L
H
T
V
R
K
Site 137
T1415
D
I
K
T
D
L
H
T
V
R
K
N
M
G
V
Site 138
Y1432
Q
H
D
V
L
F
S
Y
L
T
T
K
E
H
L
Site 139
Y1442
T
K
E
H
L
L
L
Y
G
S
I
K
V
P
H
Site 140
T1462
L
H
E
E
V
K
R
T
L
K
D
T
G
L
Y
Site 141
T1466
V
K
R
T
L
K
D
T
G
L
Y
S
H
R
H
Site 142
S1470
L
K
D
T
G
L
Y
S
H
R
H
K
R
V
G
Site 143
T1478
H
R
H
K
R
V
G
T
L
S
G
G
M
K
R
Site 144
S1480
H
K
R
V
G
T
L
S
G
G
M
K
R
K
L
Site 145
S1488
G
G
M
K
R
K
L
S
I
S
I
A
L
I
G
Site 146
S1497
S
I
A
L
I
G
G
S
R
V
V
I
L
D
E
Site 147
T1507
V
I
L
D
E
P
S
T
G
V
D
P
C
S
R
Site 148
S1513
S
T
G
V
D
P
C
S
R
R
S
I
W
D
V
Site 149
S1516
V
D
P
C
S
R
R
S
I
W
D
V
I
S
K
Site 150
S1522
R
S
I
W
D
V
I
S
K
N
K
T
A
R
T
Site 151
T1526
D
V
I
S
K
N
K
T
A
R
T
I
I
L
S
Site 152
T1529
S
K
N
K
T
A
R
T
I
I
L
S
T
H
H
Site 153
S1533
T
A
R
T
I
I
L
S
T
H
H
L
D
E
A
Site 154
S1560
G
G
L
R
C
C
G
S
P
F
Y
L
K
E
A
Site 155
Y1563
R
C
C
G
S
P
F
Y
L
K
E
A
F
G
D
Site 156
Y1572
K
E
A
F
G
D
G
Y
H
L
T
L
T
K
K
Site 157
T1575
F
G
D
G
Y
H
L
T
L
T
K
K
K
S
P
Site 158
T1577
D
G
Y
H
L
T
L
T
K
K
K
S
P
N
L
Site 159
S1581
L
T
L
T
K
K
K
S
P
N
L
N
A
N
A
Site 160
Y1631
S
T
K
V
S
G
A
Y
L
S
L
L
R
A
L
Site 161
S1668
F
L
N
L
T
K
E
S
Q
K
N
S
A
M
S
Site 162
S1672
T
K
E
S
Q
K
N
S
A
M
S
L
E
H
L
Site 163
S1675
S
Q
K
N
S
A
M
S
L
E
H
L
T
Q
K
Site 164
T1680
A
M
S
L
E
H
L
T
Q
K
K
I
G
N
S
Site 165
S1693
N
S
N
A
N
G
I
S
T
P
D
D
L
S
V
Site 166
T1694
S
N
A
N
G
I
S
T
P
D
D
L
S
V
S
Site 167
S1699
I
S
T
P
D
D
L
S
V
S
S
S
N
F
T
Site 168
S1701
T
P
D
D
L
S
V
S
S
S
N
F
T
D
R
Site 169
S1703
D
D
L
S
V
S
S
S
N
F
T
D
R
D
D
Site 170
T1706
S
V
S
S
S
N
F
T
D
R
D
D
K
I
L
Site 171
T1740
L
I
K
R
F
H
H
T
R
R
N
W
K
G
L
Site 172
T1766
T
T
A
M
G
L
G
T
L
R
N
S
S
N
S
Site 173
S1770
G
L
G
T
L
R
N
S
S
N
S
Y
P
E
I
Site 174
S1771
L
G
T
L
R
N
S
S
N
S
Y
P
E
I
Q
Site 175
S1773
T
L
R
N
S
S
N
S
Y
P
E
I
Q
I
S
Site 176
Y1774
L
R
N
S
S
N
S
Y
P
E
I
Q
I
S
P
Site 177
S1780
S
Y
P
E
I
Q
I
S
P
S
L
Y
G
T
S
Site 178
S1782
P
E
I
Q
I
S
P
S
L
Y
G
T
S
E
Q
Site 179
Y1784
I
Q
I
S
P
S
L
Y
G
T
S
E
Q
T
A
Site 180
T1786
I
S
P
S
L
Y
G
T
S
E
Q
T
A
F
Y
Site 181
Y1793
T
S
E
Q
T
A
F
Y
A
N
Y
H
P
S
T
Site 182
T1800
Y
A
N
Y
H
P
S
T
E
A
L
V
S
A
M
Site 183
S1830
L
Q
C
L
N
K
D
S
L
E
K
W
N
T
S
Site 184
T1836
D
S
L
E
K
W
N
T
S
G
E
P
I
T
N
Site 185
T1842
N
T
S
G
E
P
I
T
N
F
G
V
C
S
C
Site 186
Y1861
Q
E
C
P
K
F
N
Y
S
P
P
H
R
R
T
Site 187
S1862
E
C
P
K
F
N
Y
S
P
P
H
R
R
T
Y
Site 188
T1868
Y
S
P
P
H
R
R
T
Y
S
S
Q
V
I
Y
Site 189
Y1869
S
P
P
H
R
R
T
Y
S
S
Q
V
I
Y
N
Site 190
S1870
P
P
H
R
R
T
Y
S
S
Q
V
I
Y
N
L
Site 191
S1871
P
H
R
R
T
Y
S
S
Q
V
I
Y
N
L
T
Site 192
Y1875
T
Y
S
S
Q
V
I
Y
N
L
T
G
Q
R
V
Site 193
Y1885
T
G
Q
R
V
E
N
Y
L
I
S
T
A
N
E
Site 194
Y1898
N
E
F
V
Q
K
R
Y
G
G
W
S
F
G
L
Site 195
S1902
Q
K
R
Y
G
G
W
S
F
G
L
P
L
T
K
Site 196
T1916
K
D
L
R
F
D
I
T
G
V
P
A
N
R
T
Site 197
T1923
T
G
V
P
A
N
R
T
L
A
K
V
W
Y
D
Site 198
Y1929
R
T
L
A
K
V
W
Y
D
P
E
G
Y
H
S
Site 199
S1936
Y
D
P
E
G
Y
H
S
L
P
A
Y
L
N
S
Site 200
Y1940
G
Y
H
S
L
P
A
Y
L
N
S
L
N
N
F
Site 201
S1954
F
L
L
R
V
N
M
S
K
Y
D
A
A
R
H
Site 202
Y1956
L
R
V
N
M
S
K
Y
D
A
A
R
H
G
I
Site 203
Y1966
A
R
H
G
I
I
M
Y
S
H
P
Y
P
G
V
Site 204
Y1970
I
I
M
Y
S
H
P
Y
P
G
V
Q
D
Q
E
Site 205
Y2007
T
T
A
S
F
V
T
Y
V
V
R
E
H
Q
T
Site 206
S2124
L
S
V
V
Y
F
L
S
K
E
K
P
N
D
P
Site 207
T2132
K
E
K
P
N
D
P
T
L
E
L
I
S
E
T
Site 208
T2139
T
L
E
L
I
S
E
T
L
K
R
I
F
L
I
Site 209
S2160
G
Y
G
L
I
E
L
S
Q
Q
Q
S
V
L
D
Site 210
S2164
I
E
L
S
Q
Q
Q
S
V
L
D
F
L
K
A
Site 211
Y2172
V
L
D
F
L
K
A
Y
G
V
E
Y
P
N
E
Site 212
Y2176
L
K
A
Y
G
V
E
Y
P
N
E
T
F
E
M
Site 213
T2180
G
V
E
Y
P
N
E
T
F
E
M
N
K
L
G
Site 214
S2224
L
F
F
R
K
F
N
S
S
H
V
R
E
T
I
Site 215
S2225
F
F
R
K
F
N
S
S
H
V
R
E
T
I
D
Site 216
T2230
N
S
S
H
V
R
E
T
I
D
E
D
E
D
V
Site 217
S2246
A
E
R
L
R
V
E
S
G
A
A
E
F
D
L
Site 218
Y2257
E
F
D
L
V
Q
L
Y
C
L
T
K
T
Y
Q
Site 219
S2310
L
T
G
D
I
I
P
S
S
G
N
I
L
I
R
Site 220
S2311
T
G
D
I
I
P
S
S
G
N
I
L
I
R
N
Site 221
T2320
N
I
L
I
R
N
K
T
G
S
L
G
H
V
D
Site 222
S2322
L
I
R
N
K
T
G
S
L
G
H
V
D
S
H
Site 223
S2328
G
S
L
G
H
V
D
S
H
S
S
L
V
G
Y
Site 224
S2330
L
G
H
V
D
S
H
S
S
L
V
G
Y
C
P
Site 225
S2331
G
H
V
D
S
H
S
S
L
V
G
Y
C
P
Q
Site 226
Y2335
S
H
S
S
L
V
G
Y
C
P
Q
E
D
A
L
Site 227
Y2353
V
T
V
E
E
H
L
Y
F
Y
A
R
V
H
G
Site 228
Y2355
V
E
E
H
L
Y
F
Y
A
R
V
H
G
I
P
Site 229
T2369
P
E
K
D
I
K
E
T
V
H
K
L
L
R
R
Site 230
T2387
M
P
F
K
D
R
A
T
S
M
C
S
Y
G
T
Site 231
S2388
P
F
K
D
R
A
T
S
M
C
S
Y
G
T
K
Site 232
Y2392
R
A
T
S
M
C
S
Y
G
T
K
R
K
L
S
Site 233
S2399
Y
G
T
K
R
K
L
S
T
A
L
A
L
I
G
Site 234
T2400
G
T
K
R
K
L
S
T
A
L
A
L
I
G
K
Site 235
S2417
I
L
L
L
D
E
P
S
S
G
M
D
P
K
S
Site 236
S2418
L
L
L
D
E
P
S
S
G
M
D
P
K
S
K
Site 237
S2424
S
S
G
M
D
P
K
S
K
R
H
L
W
K
I
Site 238
S2441
E
E
V
Q
N
K
C
S
V
I
L
T
S
H
S
Site 239
T2445
N
K
C
S
V
I
L
T
S
H
S
M
E
E
C
Site 240
S2446
K
C
S
V
I
L
T
S
H
S
M
E
E
C
E
Site 241
S2472
G
K
F
Q
C
I
G
S
L
Q
H
I
K
S
R
Site 242
S2478
G
S
L
Q
H
I
K
S
R
F
G
R
G
F
T
Site 243
T2485
S
R
F
G
R
G
F
T
V
K
V
H
L
K
N
Site 244
T2511
M
Q
L
H
F
P
K
T
Y
L
K
D
Q
H
L
Site 245
T2544
D
L
L
E
T
N
K
T
A
L
N
I
T
N
F
Site 246
S2571
N
F
A
K
D
Q
K
S
Y
E
T
A
D
T
S
Site 247
T2574
K
D
Q
K
S
Y
E
T
A
D
T
S
S
Q
G
Site 248
T2577
K
S
Y
E
T
A
D
T
S
S
Q
G
S
T
I
Site 249
S2578
S
Y
E
T
A
D
T
S
S
Q
G
S
T
I
S
Site 250
S2579
Y
E
T
A
D
T
S
S
Q
G
S
T
I
S
V
Site 251
S2582
A
D
T
S
S
Q
G
S
T
I
S
V
D
S
Q
Site 252
T2583
D
T
S
S
Q
G
S
T
I
S
V
D
S
Q
D
Site 253
S2585
S
S
Q
G
S
T
I
S
V
D
S
Q
D
D
Q
Site 254
S2588
G
S
T
I
S
V
D
S
Q
D
D
Q
M
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation