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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF589
Full Name:
Zinc finger protein 589
Alias:
Stem cell zinc finger 1; SZF1; Zinc finger 589; ZN589
Type:
Transcription protein, repressor. Krueppel C2H2-type zinc-finger protein family.
Mass (Da):
41189
Number AA:
364
UniProt ID:
Q86UQ0
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
E
A
L
P
A
K
D
S
A
W
P
W
E
E
K
Site 2
Y31
P
W
E
E
K
P
R
Y
L
G
P
V
T
F
E
Site 3
S53
E
A
E
W
K
R
L
S
L
E
Q
R
N
L
Y
Site 4
Y60
S
L
E
Q
R
N
L
Y
K
E
V
M
L
E
N
Site 5
S73
E
N
L
R
N
L
V
S
L
A
E
S
K
P
E
Site 6
S77
N
L
V
S
L
A
E
S
K
P
E
V
H
T
C
Site 7
S93
S
C
P
L
A
F
G
S
Q
Q
F
L
S
Q
D
Site 8
S98
F
G
S
Q
Q
F
L
S
Q
D
E
L
H
N
H
Site 9
S129
C
P
E
D
Q
P
Q
S
Q
H
P
S
D
K
N
Site 10
S133
Q
P
Q
S
Q
H
P
S
D
K
N
H
R
G
A
Site 11
S157
G
V
R
P
L
F
W
S
T
N
E
R
G
A
L
Site 12
S177
L
F
Q
R
P
P
I
S
S
W
G
G
N
R
I
Site 13
S178
F
Q
R
P
P
I
S
S
W
G
G
N
R
I
L
Site 14
S190
R
I
L
E
I
Q
L
S
P
A
Q
N
A
S
S
Site 15
S204
S
E
E
V
D
R
I
S
K
R
A
E
T
P
G
Site 16
T209
R
I
S
K
R
A
E
T
P
G
F
G
A
V
T
Site 17
T237
L
F
R
Q
K
A
V
T
A
E
K
S
S
D
K
Site 18
S242
A
V
T
A
E
K
S
S
D
K
R
Q
S
Q
V
Site 19
S247
K
S
S
D
K
R
Q
S
Q
V
C
R
E
C
G
Site 20
S258
R
E
C
G
R
G
F
S
R
K
S
Q
L
I
I
Site 21
S261
G
R
G
F
S
R
K
S
Q
L
I
I
H
Q
R
Site 22
T269
Q
L
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 23
T271
I
I
H
Q
R
T
H
T
G
E
K
P
Y
V
C
Site 24
Y276
T
H
T
G
E
K
P
Y
V
C
G
E
C
G
R
Site 25
S289
G
R
G
F
I
V
E
S
V
L
R
N
H
L
S
Site 26
S296
S
V
L
R
N
H
L
S
T
H
S
G
E
K
P
Site 27
T297
V
L
R
N
H
L
S
T
H
S
G
E
K
P
Y
Site 28
Y304
T
H
S
G
E
K
P
Y
V
C
S
H
C
G
R
Site 29
S314
S
H
C
G
R
G
F
S
C
K
P
Y
L
I
R
Site 30
Y318
R
G
F
S
C
K
P
Y
L
I
R
H
Q
R
T
Site 31
T327
I
R
H
Q
R
T
H
T
R
E
K
S
F
M
C
Site 32
S345
G
R
G
F
R
E
K
S
E
L
I
K
H
Q
R
Site 33
T355
I
K
H
Q
R
I
H
T
G
D
K
P
Y
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation