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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCA13
Full Name:
ATP-binding cassette sub-family A member 13
Alias:
ABCAD; ATP binding cassette transporter A13; ATP-binding cassette, sub-family A (ABC1) member 13; FLJ33876; FLJ33951
Type:
Membrane protein, integral
Mass (Da):
576240
Number AA:
UniProt ID:
Q86UQ4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y51
R
F
Q
E
P
P
R
Y
R
D
I
C
Y
L
Q
Site 2
Y56
P
R
Y
R
D
I
C
Y
L
Q
P
R
D
L
P
Site 3
S80
S
L
L
C
N
T
G
S
R
C
R
N
F
S
Y
Site 4
S86
G
S
R
C
R
N
F
S
Y
E
G
S
M
E
H
Site 5
Y87
S
R
C
R
N
F
S
Y
E
G
S
M
E
H
H
Site 6
S98
M
E
H
H
F
R
L
S
R
F
Q
T
A
A
D
Site 7
T102
F
R
L
S
R
F
Q
T
A
A
D
P
K
K
V
Site 8
S143
K
R
L
W
V
E
R
S
N
T
P
D
S
S
Y
Site 9
T145
L
W
V
E
R
S
N
T
P
D
S
S
Y
G
S
Site 10
S148
E
R
S
N
T
P
D
S
S
Y
G
S
S
F
F
Site 11
S149
R
S
N
T
P
D
S
S
Y
G
S
S
F
F
T
Site 12
Y150
S
N
T
P
D
S
S
Y
G
S
S
F
F
T
M
Site 13
S152
T
P
D
S
S
Y
G
S
S
F
F
T
M
D
L
Site 14
S153
P
D
S
S
Y
G
S
S
F
F
T
M
D
L
N
Site 15
T156
S
Y
G
S
S
F
F
T
M
D
L
N
K
T
E
Site 16
S171
E
V
I
L
K
L
E
S
L
H
Q
Q
P
H
I
Site 17
T190
L
L
L
P
R
L
H
T
S
H
D
H
V
E
D
Site 18
T227
D
W
L
P
L
N
Q
T
F
S
Q
V
S
E
L
Site 19
Y274
W
D
P
Q
K
V
Q
Y
D
L
K
S
Q
F
G
Site 20
S278
K
V
Q
Y
D
L
K
S
Q
F
G
F
D
D
L
Site 21
T287
F
G
F
D
D
L
H
T
E
Q
I
L
N
S
S
Site 22
S305
K
E
I
P
T
D
T
S
L
E
K
M
V
C
S
Site 23
S316
M
V
C
S
V
L
S
S
T
S
E
D
E
A
E
Site 24
Y341
K
W
S
E
A
K
N
Y
L
V
H
A
V
S
W
Site 25
S363
F
V
Q
W
Q
Q
G
S
L
L
Q
K
T
L
T
Site 26
T368
Q
G
S
L
L
Q
K
T
L
T
G
M
G
H
S
Site 27
T370
S
L
L
Q
K
T
L
T
G
M
G
H
S
L
E
Site 28
S375
T
L
T
G
M
G
H
S
L
E
A
L
R
N
Q
Site 29
S408
L
L
L
N
D
S
L
S
A
D
G
P
K
D
N
Site 30
T417
D
G
P
K
D
N
H
T
F
P
K
I
L
Q
H
Site 31
S430
Q
H
L
W
K
L
Q
S
L
L
Q
N
L
P
Q
Site 32
S511
V
C
P
N
G
R
F
S
E
K
E
V
F
L
P
Site 33
S523
F
L
P
P
G
N
S
S
I
W
G
G
L
Q
G
Site 34
Y534
G
L
Q
G
L
L
C
Y
C
N
S
S
E
T
S
Site 35
S538
L
L
C
Y
C
N
S
S
E
T
S
V
L
N
K
Site 36
S541
Y
C
N
S
S
E
T
S
V
L
N
K
L
L
G
Site 37
Y575
S
V
L
I
P
E
E
Y
L
D
W
Q
E
L
E
Site 38
S586
Q
E
L
E
M
Q
L
S
E
A
S
L
S
C
T
Site 39
S589
E
M
Q
L
S
E
A
S
L
S
C
T
R
L
F
Site 40
S604
L
L
L
G
A
D
P
S
P
E
N
D
V
F
S
Site 41
S612
P
E
N
D
V
F
S
S
D
C
K
H
Q
L
V
Site 42
Y639
F
F
L
E
Q
A
Y
Y
W
K
A
F
K
K
F
Site 43
Y656
K
T
C
E
V
A
Q
Y
V
N
M
Q
E
S
F
Site 44
S674
L
L
A
F
P
E
E
S
P
C
F
E
E
N
M
Site 45
Y690
W
K
M
I
S
D
N
Y
F
Q
F
L
N
N
L
Site 46
S700
F
L
N
N
L
L
K
S
P
T
A
S
I
S
R
Site 47
T702
N
N
L
L
K
S
P
T
A
S
I
S
R
A
L
Site 48
S759
S
I
V
P
S
F
H
S
L
P
S
L
T
E
D
Site 49
S762
P
S
F
H
S
L
P
S
L
T
E
D
I
L
N
Site 50
S772
E
D
I
L
N
I
S
S
L
W
T
N
H
L
K
Site 51
T775
L
N
I
S
S
L
W
T
N
H
L
K
S
L
K
Site 52
S780
L
W
T
N
H
L
K
S
L
K
R
D
P
S
A
Site 53
S786
K
S
L
K
R
D
P
S
A
T
D
A
Q
K
L
Site 54
T788
L
K
R
D
P
S
A
T
D
A
Q
K
L
L
E
Site 55
Y840
K
L
L
E
L
W
A
Y
G
I
S
K
G
K
R
Site 56
S868
V
P
E
N
E
I
L
S
T
S
F
N
F
S
Q
Site 57
T869
P
E
N
E
I
L
S
T
S
F
N
F
S
Q
L
Site 58
S870
E
N
E
I
L
S
T
S
F
N
F
S
Q
L
F
Site 59
S874
L
S
T
S
F
N
F
S
Q
L
F
H
S
D
W
Site 60
S879
N
F
S
Q
L
F
H
S
D
W
P
K
S
P
A
Site 61
T919
Q
I
S
E
A
L
N
T
V
Y
A
I
R
N
A
Site 62
Y921
S
E
A
L
N
T
V
Y
A
I
R
N
A
S
D
Site 63
S931
R
N
A
S
D
L
F
S
A
L
S
E
P
Q
K
Site 64
S934
S
D
L
F
S
A
L
S
E
P
Q
K
Q
E
V
Site 65
S958
N
V
F
Q
D
K
D
S
A
L
L
L
Q
I
Y
Site 66
Y973
S
S
F
Y
R
Y
I
Y
E
L
L
N
I
Q
S
Site 67
S980
Y
E
L
L
N
I
Q
S
R
G
S
S
L
T
F
Site 68
S983
L
N
I
Q
S
R
G
S
S
L
T
F
L
T
Q
Site 69
S984
N
I
Q
S
R
G
S
S
L
T
F
L
T
Q
I
Site 70
T986
Q
S
R
G
S
S
L
T
F
L
T
Q
I
S
K
Site 71
S1046
F
L
E
L
Q
A
Q
S
F
M
S
T
E
G
Q
Site 72
T1050
Q
A
Q
S
F
M
S
T
E
G
Q
E
L
E
V
Site 73
T1060
Q
E
L
E
V
I
H
T
T
L
T
G
L
K
Q
Site 74
Y1082
F
R
I
S
L
F
Q
Y
M
S
Q
F
F
N
S
Site 75
S1089
Y
M
S
Q
F
F
N
S
S
V
E
D
L
L
D
Site 76
S1090
M
S
Q
F
F
N
S
S
V
E
D
L
L
D
N
Site 77
S1109
S
D
N
K
H
I
S
S
V
N
Y
S
T
S
E
Site 78
Y1112
K
H
I
S
S
V
N
Y
S
T
S
E
E
S
S
Site 79
S1113
H
I
S
S
V
N
Y
S
T
S
E
E
S
S
F
Site 80
T1114
I
S
S
V
N
Y
S
T
S
E
E
S
S
F
V
Site 81
S1115
S
S
V
N
Y
S
T
S
E
E
S
S
F
V
F
Site 82
S1119
Y
S
T
S
E
E
S
S
F
V
F
P
L
A
Q
Site 83
S1195
D
D
V
K
V
S
K
S
C
Q
G
I
L
P
T
Site 84
T1202
S
C
Q
G
I
L
P
T
H
N
V
A
R
L
I
Site 85
S1256
N
L
E
Q
V
E
K
S
L
F
T
M
E
A
A
Site 86
T1269
A
A
L
H
Q
L
K
T
F
P
F
N
E
S
T
Site 87
S1275
K
T
F
P
F
N
E
S
T
S
R
E
F
L
N
Site 88
T1276
T
F
P
F
N
E
S
T
S
R
E
F
L
N
S
Site 89
Y1297
E
F
S
S
T
S
E
Y
I
V
R
N
L
D
S
Site 90
S1304
Y
I
V
R
N
L
D
S
I
N
D
F
L
S
N
Site 91
S1310
D
S
I
N
D
F
L
S
N
N
L
T
N
Y
G
Site 92
T1314
D
F
L
S
N
N
L
T
N
Y
G
E
K
F
E
Site 93
Y1316
L
S
N
N
L
T
N
Y
G
E
K
F
E
N
I
Site 94
T1325
E
K
F
E
N
I
I
T
E
L
R
E
A
I
V
Site 95
S1338
I
V
F
L
R
N
V
S
H
D
R
D
L
F
S
Site 96
Y1364
I
L
E
D
G
F
L
Y
V
N
T
S
Q
R
M
Site 97
T1377
R
M
L
R
I
L
D
T
L
N
S
T
F
S
S
Site 98
S1380
R
I
L
D
T
L
N
S
T
F
S
S
E
N
T
Site 99
T1381
I
L
D
T
L
N
S
T
F
S
S
E
N
T
I
Site 100
S1383
D
T
L
N
S
T
F
S
S
E
N
T
I
S
S
Site 101
S1384
T
L
N
S
T
F
S
S
E
N
T
I
S
S
L
Site 102
T1387
S
T
F
S
S
E
N
T
I
S
S
L
K
G
C
Site 103
S1390
S
S
E
N
T
I
S
S
L
K
G
C
I
V
W
Site 104
S1408
I
N
H
L
Y
L
L
S
N
S
S
F
S
Q
G
Site 105
S1410
H
L
Y
L
L
S
N
S
S
F
S
Q
G
R
L
Site 106
S1411
L
Y
L
L
S
N
S
S
F
S
Q
G
R
L
Q
Site 107
S1413
L
L
S
N
S
S
F
S
Q
G
R
L
Q
N
I
Site 108
S1450
N
I
K
K
P
L
C
S
S
N
G
S
H
I
N
Site 109
S1503
S
T
K
Q
V
R
M
S
I
N
N
L
T
T
D
Site 110
S1515
T
T
D
F
D
F
A
S
Q
S
N
W
R
Y
F
Site 111
Y1521
A
S
Q
S
N
W
R
Y
F
T
E
L
I
L
R
Site 112
T1523
Q
S
N
W
R
Y
F
T
E
L
I
L
R
P
I
Site 113
S1533
I
L
R
P
I
E
M
S
D
E
I
P
N
Q
F
Site 114
T1549
N
I
W
L
H
L
I
T
L
G
K
E
F
Q
K
Site 115
Y1562
Q
K
L
V
K
G
I
Y
F
N
I
L
E
N
N
Site 116
S1571
N
I
L
E
N
N
S
S
S
K
T
E
N
L
L
Site 117
T1574
E
N
N
S
S
S
K
T
E
N
L
L
N
I
F
Site 118
S1584
L
L
N
I
F
A
T
S
P
K
E
K
D
V
N
Site 119
S1592
P
K
E
K
D
V
N
S
V
G
N
S
I
Y
H
Site 120
S1596
D
V
N
S
V
G
N
S
I
Y
H
L
A
S
Y
Site 121
S1609
S
Y
L
A
F
S
L
S
H
D
L
Q
N
S
P
Site 122
S1615
L
S
H
D
L
Q
N
S
P
K
I
I
I
S
P
Site 123
S1621
N
S
P
K
I
I
I
S
P
E
I
M
K
A
T
Site 124
S1665
Q
A
L
K
K
V
T
S
V
M
R
T
L
K
K
Site 125
T1669
K
V
T
S
V
M
R
T
L
K
K
A
D
I
D
Site 126
S1722
K
F
A
D
S
S
H
S
W
N
V
N
H
L
L
Site 127
Y1773
T
E
G
L
K
D
V
Y
S
F
T
L
L
H
G
Site 128
S1836
N
S
G
F
R
Q
N
S
K
I
D
P
C
N
V
Site 129
S1865
I
L
D
H
F
H
L
S
P
Q
G
E
D
S
P
Site 130
S1871
L
S
P
Q
G
E
D
S
P
C
S
N
E
S
S
Site 131
S1874
Q
G
E
D
S
P
C
S
N
E
S
S
R
M
E
Site 132
S1877
D
S
P
C
S
N
E
S
S
R
M
E
I
T
R
Site 133
S1878
S
P
C
S
N
E
S
S
R
M
E
I
T
R
K
Site 134
S1898
H
E
L
V
D
W
N
S
I
L
L
E
L
S
E
Site 135
T1916
V
N
I
S
L
V
K
T
V
Q
K
F
W
H
K
Site 136
S1931
I
L
P
F
V
P
P
S
I
N
Q
T
R
D
S
Site 137
T1935
V
P
P
S
I
N
Q
T
R
D
S
I
S
E
L
Site 138
S1938
S
I
N
Q
T
R
D
S
I
S
E
L
C
P
S
Site 139
S1940
N
Q
T
R
D
S
I
S
E
L
C
P
S
G
S
Site 140
S1947
S
E
L
C
P
S
G
S
I
K
Q
V
A
L
Q
Site 141
S1978
E
N
I
L
D
K
L
S
S
L
N
K
I
L
N
Site 142
T1992
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N
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D
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V
Q
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I
I
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T2005
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S
S
N
L
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S2014
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L
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S2018
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W
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L
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S2024
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S
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S2038
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T
F
Y
R
D
Q
Site 294
T3864
V
V
Q
D
L
S
L
T
F
Y
R
D
Q
I
T
Site 295
Y3866
Q
D
L
S
L
T
F
Y
R
D
Q
I
T
A
L
Site 296
T3871
T
F
Y
R
D
Q
I
T
A
L
L
G
T
N
G
Site 297
S3911
K
N
L
Q
T
D
L
S
R
V
R
M
E
L
G
Site 298
T3966
T
L
Q
D
V
D
L
T
Q
H
Q
H
K
Q
T
Site 299
S3977
H
K
Q
T
R
A
L
S
G
G
L
K
R
K
L
Site 300
S4004
V
V
L
D
E
P
T
S
G
V
D
P
C
S
R
Site 301
S4010
T
S
G
V
D
P
C
S
R
H
S
L
W
D
I
Site 302
S4013
V
D
P
C
S
R
H
S
L
W
D
I
L
L
K
Site 303
T4030
E
G
R
T
I
I
F
T
T
H
H
L
D
E
A
Site 304
T4072
Y
G
Q
G
L
R
L
T
L
T
R
Q
P
S
V
Site 305
T4074
Q
G
L
R
L
T
L
T
R
Q
P
S
V
L
E
Site 306
S4078
L
T
L
T
R
Q
P
S
V
L
E
A
H
D
L
Site 307
S4107
P
Q
A
F
L
K
D
S
S
G
S
E
L
T
Y
Site 308
S4108
Q
A
F
L
K
D
S
S
G
S
E
L
T
Y
T
Site 309
Y4114
S
S
G
S
E
L
T
Y
T
I
P
K
D
T
D
Site 310
T4115
S
G
S
E
L
T
Y
T
I
P
K
D
T
D
K
Site 311
T4142
N
L
H
Q
L
H
L
T
G
Y
G
I
S
D
T
Site 312
S4162
F
L
M
L
L
Q
D
S
N
K
K
S
H
I
A
Site 313
S4166
L
Q
D
S
N
K
K
S
H
I
A
L
G
T
E
Site 314
T4182
E
L
Q
N
H
R
P
T
G
H
L
S
G
Y
C
Site 315
S4186
H
R
P
T
G
H
L
S
G
Y
C
G
S
L
A
Site 316
Y4188
P
T
G
H
L
S
G
Y
C
G
S
L
A
R
P
Site 317
T4219
L
A
R
R
L
R
R
T
L
R
A
G
K
S
T
Site 318
Y4253
V
R
P
L
A
T
E
Y
P
P
L
R
L
T
P
Site 319
T4259
E
Y
P
P
L
R
L
T
P
G
H
Y
Q
R
A
Site 320
Y4263
L
R
L
T
P
G
H
Y
Q
R
A
E
T
Y
F
Site 321
T4268
G
H
Y
Q
R
A
E
T
Y
F
F
S
S
G
G
Site 322
Y4269
H
Y
Q
R
A
E
T
Y
F
F
S
S
G
G
D
Site 323
S4273
A
E
T
Y
F
F
S
S
G
G
D
N
L
D
L
Site 324
T4281
G
G
D
N
L
D
L
T
R
V
L
L
R
K
F
Site 325
T4310
K
N
S
S
C
W
R
T
D
P
F
S
H
P
E
Site 326
S4333
K
C
P
N
R
S
A
S
A
P
Y
L
T
N
H
Site 327
S4349
G
H
T
L
L
N
L
S
G
F
N
M
E
E
Y
Site 328
Y4356
S
G
F
N
M
E
E
Y
L
L
A
P
S
E
K
Site 329
S4361
E
E
Y
L
L
A
P
S
E
K
P
R
L
G
G
Site 330
S4370
K
P
R
L
G
G
W
S
F
G
L
K
I
P
S
Site 331
S4377
S
F
G
L
K
I
P
S
E
A
G
G
A
N
G
Site 332
S4387
G
G
A
N
G
N
I
S
K
P
P
T
L
A
K
Site 333
T4391
G
N
I
S
K
P
P
T
L
A
K
V
W
Y
N
Site 334
Y4397
P
T
L
A
K
V
W
Y
N
Q
K
G
F
H
S
Site 335
S4404
Y
N
Q
K
G
F
H
S
L
P
S
Y
L
N
H
Site 336
Y4408
G
F
H
S
L
P
S
Y
L
N
H
L
N
N
L
Site 337
Y4430
P
T
V
D
W
R
Q
Y
G
I
T
L
Y
S
H
Site 338
Y4435
R
Q
Y
G
I
T
L
Y
S
H
P
Y
G
G
A
Site 339
S4436
Q
Y
G
I
T
L
Y
S
H
P
Y
G
G
A
L
Site 340
S4452
N
E
D
K
I
L
E
S
I
R
Q
C
G
V
A
Site 341
S4492
A
K
R
L
Q
H
I
S
G
L
G
Y
R
M
Y
Site 342
Y4499
S
G
L
G
Y
R
M
Y
W
F
T
N
F
L
Y
Site 343
S4558
L
P
W
M
Y
L
M
S
R
I
F
S
S
S
D
Site 344
S4596
P
R
L
L
A
I
I
S
K
A
K
N
L
Q
N
Site 345
Y4605
A
K
N
L
Q
N
I
Y
D
V
L
K
W
V
F
Site 346
Y4629
Q
G
L
V
E
L
C
Y
N
Q
I
K
Y
D
L
Site 347
Y4634
L
C
Y
N
Q
I
K
Y
D
L
T
H
N
F
G
Site 348
T4637
N
Q
I
K
Y
D
L
T
H
N
F
G
I
D
S
Site 349
Y4645
H
N
F
G
I
D
S
Y
V
S
P
F
E
M
N
Site 350
S4687
L
R
W
P
R
G
H
S
T
L
Q
G
T
V
K
Site 351
T4688
R
W
P
R
G
H
S
T
L
Q
G
T
V
K
S
Site 352
T4692
G
H
S
T
L
Q
G
T
V
K
S
S
K
D
T
Site 353
T4699
T
V
K
S
S
K
D
T
D
V
E
K
E
E
K
Site 354
Y4721
N
G
D
I
L
V
L
Y
N
L
S
K
H
Y
R
Site 355
Y4727
L
Y
N
L
S
K
H
Y
R
R
F
F
Q
N
I
Site 356
S4761
G
V
N
G
A
G
K
S
T
T
F
K
M
L
N
Site 357
T4763
N
G
A
G
K
S
T
T
F
K
M
L
N
G
E
Site 358
T4782
S
G
H
A
I
I
R
T
P
M
G
D
A
V
D
Site 359
T4814
D
A
L
D
E
L
L
T
G
W
E
H
L
Y
Y
Site 360
Y4820
L
T
G
W
E
H
L
Y
Y
Y
C
S
L
R
G
Site 361
Y4821
T
G
W
E
H
L
Y
Y
Y
C
S
L
R
G
I
Site 362
Y4822
G
W
E
H
L
Y
Y
Y
C
S
L
R
G
I
P
Site 363
S4885
L
L
L
D
E
P
S
S
G
M
D
P
C
S
K
Site 364
T4898
S
K
R
Y
L
W
Q
T
I
M
K
E
V
R
E
Site 365
T4912
E
G
C
A
A
V
L
T
S
H
S
M
E
E
C
Site 366
S4939
G
S
F
K
C
L
G
S
P
Q
H
I
K
N
R
Site 367
Y4951
K
N
R
F
G
D
G
Y
T
V
K
V
W
L
C
Site 368
T4966
K
E
A
N
Q
H
C
T
V
S
D
H
L
K
L
Site 369
Y4974
V
S
D
H
L
K
L
Y
F
P
G
I
Q
F
K
Site 370
Y4990
Q
H
L
N
L
L
E
Y
H
V
P
K
R
W
G
Site 371
T5011
K
V
I
E
N
N
K
T
F
L
N
I
K
H
Y
Site 372
T5023
K
H
Y
S
I
N
Q
T
T
L
E
Q
V
F
I
Site 373
T5024
H
Y
S
I
N
Q
T
T
L
E
Q
V
F
I
N
Site 374
T5039
F
A
S
E
Q
Q
Q
T
L
Q
S
T
L
D
P
Site 375
T5043
Q
Q
Q
T
L
Q
S
T
L
D
P
S
T
D
S
Site 376
S5047
L
Q
S
T
L
D
P
S
T
D
S
H
H
T
H
Site 377
T5048
Q
S
T
L
D
P
S
T
D
S
H
H
T
H
H
Site 378
S5050
T
L
D
P
S
T
D
S
H
H
T
H
H
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation