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Updated November 2019
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Protein Info
Short Name:
RIMS1
Full Name:
Regulating synaptic membrane exocytosis protein 1
Alias:
CORD7; KIAA0340; Rab3-interacting molecule; Rab3-interacting molecule 1; RAB3IP2; Regulating synaptic membrane exocytosis 1; RIM; RIM 1; RIM1; RIM1alpha
Type:
Adaptor/scaffold; Vesicle protein
Mass (Da):
189073
Number AA:
1692
UniProt ID:
Q86UR5
International Prot ID:
IPI00339390
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0019898
GO:0042734
Uniprot
OncoNet
Molecular Function:
GO:0017137
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0017156
GO:0006886
GO:0006944
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
P
R
G
P
R
P
P
T
V
P
P
P
M
Q
E
Site 2
S26
M
Q
E
L
P
D
L
S
H
L
T
E
E
E
R
Site 3
T69
A
K
P
A
A
C
K
T
P
R
N
A
E
N
Q
Site 4
S81
E
N
Q
P
H
Q
P
S
P
R
L
H
Q
Q
F
Site 5
Y105
I
G
E
E
A
R
R
Y
Q
G
E
H
K
D
D
Site 6
S148
A
R
C
G
G
R
V
S
L
R
S
N
N
E
D
Site 7
S151
G
G
R
V
S
L
R
S
N
N
E
D
K
V
V
Site 8
T173
R
K
Q
Q
E
I
L
T
K
S
G
A
W
F
F
Site 9
S175
Q
Q
E
I
L
T
K
S
G
A
W
F
F
G
S
Site 10
S182
S
G
A
W
F
F
G
S
G
P
Q
Q
T
S
Q
Site 11
S188
G
S
G
P
Q
Q
T
S
Q
D
G
T
L
S
D
Site 12
T192
Q
Q
T
S
Q
D
G
T
L
S
D
T
A
T
G
Site 13
S194
T
S
Q
D
G
T
L
S
D
T
A
T
G
A
G
Site 14
T196
Q
D
G
T
L
S
D
T
A
T
G
A
G
S
E
Site 15
T198
G
T
L
S
D
T
A
T
G
A
G
S
E
V
P
Site 16
S216
K
A
R
L
Q
E
R
S
R
S
Q
T
P
L
S
Site 17
S218
R
L
Q
E
R
S
R
S
Q
T
P
L
S
T
A
Site 18
T220
Q
E
R
S
R
S
Q
T
P
L
S
T
A
A
A
Site 19
S223
S
R
S
Q
T
P
L
S
T
A
A
A
S
S
Q
Site 20
T224
R
S
Q
T
P
L
S
T
A
A
A
S
S
Q
D
Site 21
S228
P
L
S
T
A
A
A
S
S
Q
D
A
A
P
P
Site 22
S229
L
S
T
A
A
A
S
S
Q
D
A
A
P
P
S
Site 23
S236
S
Q
D
A
A
P
P
S
A
P
P
D
R
S
K
Site 24
S242
P
S
A
P
P
D
R
S
K
G
A
E
P
S
Q
Site 25
S248
R
S
K
G
A
E
P
S
Q
Q
A
L
G
P
E
Site 26
S260
G
P
E
Q
K
Q
A
S
S
R
S
R
S
E
P
Site 27
S261
P
E
Q
K
Q
A
S
S
R
S
R
S
E
P
P
Site 28
S263
Q
K
Q
A
S
S
R
S
R
S
E
P
P
R
E
Site 29
S265
Q
A
S
S
R
S
R
S
E
P
P
R
E
R
K
Site 30
T274
P
P
R
E
R
K
K
T
P
G
L
S
E
Q
N
Site 31
S278
R
K
K
T
P
G
L
S
E
Q
N
G
K
G
A
Site 32
S288
N
G
K
G
A
L
K
S
E
R
K
R
V
P
K
Site 33
S297
R
K
R
V
P
K
T
S
A
Q
P
V
E
G
A
Site 34
S316
E
R
K
E
R
R
E
S
R
R
L
E
K
G
R
Site 35
S324
R
R
L
E
K
G
R
S
Q
D
Y
P
D
T
P
Site 36
Y327
E
K
G
R
S
Q
D
Y
P
D
T
P
E
K
R
Site 37
T330
R
S
Q
D
Y
P
D
T
P
E
K
R
D
E
G
Site 38
Y351
K
Q
R
K
E
E
D
Y
Q
T
R
Y
R
S
D
Site 39
T353
R
K
E
E
D
Y
Q
T
R
Y
R
S
D
P
N
Site 40
S357
D
Y
Q
T
R
Y
R
S
D
P
N
L
A
R
Y
Site 41
Y364
S
D
P
N
L
A
R
Y
P
V
K
P
P
P
E
Site 42
S382
M
R
M
H
A
R
V
S
R
A
R
H
E
R
R
Site 43
S391
A
R
H
E
R
R
H
S
D
V
A
L
P
R
T
Site 44
S420
A
P
A
A
A
R
A
S
P
P
D
S
P
R
A
Site 45
S424
A
R
A
S
P
P
D
S
P
R
A
Y
S
A
E
Site 46
Y428
P
P
D
S
P
R
A
Y
S
A
E
R
T
A
E
Site 47
S429
P
D
S
P
R
A
Y
S
A
E
R
T
A
E
T
Site 48
T445
A
P
G
A
K
Q
L
T
N
H
S
P
P
A
P
Site 49
S448
A
K
Q
L
T
N
H
S
P
P
A
P
R
H
G
Site 50
S474
Q
E
P
L
R
K
Q
S
R
L
D
P
S
S
A
Site 51
S479
K
Q
S
R
L
D
P
S
S
A
V
L
M
R
K
Site 52
S480
Q
S
R
L
D
P
S
S
A
V
L
M
R
K
A
Site 53
T494
A
K
R
E
K
V
E
T
M
L
R
N
D
S
L
Site 54
S500
E
T
M
L
R
N
D
S
L
S
S
D
Q
S
E
Site 55
S502
M
L
R
N
D
S
L
S
S
D
Q
S
E
S
V
Site 56
S503
L
R
N
D
S
L
S
S
D
Q
S
E
S
V
R
Site 57
S506
D
S
L
S
S
D
Q
S
E
S
V
R
P
S
P
Site 58
S508
L
S
S
D
Q
S
E
S
V
R
P
S
P
P
K
Site 59
S512
Q
S
E
S
V
R
P
S
P
P
K
P
H
R
S
Site 60
S519
S
P
P
K
P
H
R
S
K
R
G
G
K
K
R
Site 61
S529
G
G
K
K
R
Q
M
S
V
S
S
S
E
E
E
Site 62
S531
K
K
R
Q
M
S
V
S
S
S
E
E
E
G
V
Site 63
S533
R
Q
M
S
V
S
S
S
E
E
E
G
V
S
T
Site 64
S539
S
S
E
E
E
G
V
S
T
P
E
Y
T
S
C
Site 65
T540
S
E
E
E
G
V
S
T
P
E
Y
T
S
C
E
Site 66
Y543
E
G
V
S
T
P
E
Y
T
S
C
E
D
V
E
Site 67
S553
C
E
D
V
E
L
E
S
E
S
V
S
E
K
G
Site 68
S555
D
V
E
L
E
S
E
S
V
S
E
K
G
D
L
Site 69
S557
E
L
E
S
E
S
V
S
E
K
G
D
L
D
Y
Site 70
Y564
S
E
K
G
D
L
D
Y
Y
W
L
D
P
A
T
Site 71
Y565
E
K
G
D
L
D
Y
Y
W
L
D
P
A
T
W
Site 72
S574
L
D
P
A
T
W
H
S
R
E
T
S
P
I
S
Site 73
T577
A
T
W
H
S
R
E
T
S
P
I
S
S
H
P
Site 74
S578
T
W
H
S
R
E
T
S
P
I
S
S
H
P
V
Site 75
S581
S
R
E
T
S
P
I
S
S
H
P
V
T
W
Q
Site 76
S582
R
E
T
S
P
I
S
S
H
P
V
T
W
Q
P
Site 77
T586
P
I
S
S
H
P
V
T
W
Q
P
S
K
E
G
Site 78
T606
R
V
I
L
N
K
R
T
T
M
P
K
D
S
G
Site 79
T607
V
I
L
N
K
R
T
T
M
P
K
D
S
G
A
Site 80
T636
G
R
L
G
A
F
I
T
K
V
K
K
G
S
L
Site 81
S642
I
T
K
V
K
K
G
S
L
A
D
V
V
G
H
Site 82
S681
N
I
I
L
E
S
K
S
E
P
Q
V
E
I
I
Site 83
S702
D
I
P
R
I
P
E
S
S
H
P
P
L
E
S
Site 84
S703
I
P
R
I
P
E
S
S
H
P
P
L
E
S
S
Site 85
S709
S
S
H
P
P
L
E
S
S
S
S
S
F
E
S
Site 86
S710
S
H
P
P
L
E
S
S
S
S
S
F
E
S
Q
Site 87
S711
H
P
P
L
E
S
S
S
S
S
F
E
S
Q
K
Site 88
S712
P
P
L
E
S
S
S
S
S
F
E
S
Q
K
M
Site 89
S713
P
L
E
S
S
S
S
S
F
E
S
Q
K
M
E
Site 90
S716
S
S
S
S
S
F
E
S
Q
K
M
E
R
P
S
Site 91
S723
S
Q
K
M
E
R
P
S
I
S
V
I
S
P
T
Site 92
S725
K
M
E
R
P
S
I
S
V
I
S
P
T
S
P
Site 93
S728
R
P
S
I
S
V
I
S
P
T
S
P
G
A
L
Site 94
T730
S
I
S
V
I
S
P
T
S
P
G
A
L
K
D
Site 95
S731
I
S
V
I
S
P
T
S
P
G
A
L
K
D
A
Site 96
S747
Q
V
L
P
G
Q
L
S
V
K
L
W
Y
D
K
Site 97
Y752
Q
L
S
V
K
L
W
Y
D
K
V
G
H
Q
L
Site 98
Y781
D
G
R
P
R
N
P
Y
V
K
M
Y
F
L
P
Site 99
Y785
R
N
P
Y
V
K
M
Y
F
L
P
D
R
S
D
Site 100
S794
L
P
D
R
S
D
K
S
K
R
R
T
K
T
V
Site 101
T798
S
D
K
S
K
R
R
T
K
T
V
K
K
I
L
Site 102
T800
K
S
K
R
R
T
K
T
V
K
K
I
L
E
P
Site 103
Y815
K
W
N
Q
T
F
V
Y
S
H
V
H
R
R
D
Site 104
T831
R
E
R
M
L
E
I
T
V
W
D
Q
P
R
V
Site 105
S843
P
R
V
Q
E
E
E
S
E
F
L
G
E
I
L
Site 106
Y865
L
D
D
E
P
H
W
Y
K
L
Q
T
H
D
E
Site 107
T869
P
H
W
Y
K
L
Q
T
H
D
E
S
S
L
P
Site 108
S873
K
L
Q
T
H
D
E
S
S
L
P
L
P
Q
P
Site 109
S874
L
Q
T
H
D
E
S
S
L
P
L
P
Q
P
S
Site 110
S881
S
L
P
L
P
Q
P
S
P
F
M
P
R
R
H
Site 111
S893
R
R
H
I
H
G
E
S
S
S
K
K
L
Q
R
Site 112
S901
S
S
K
K
L
Q
R
S
Q
R
I
S
D
S
D
Site 113
S905
L
Q
R
S
Q
R
I
S
D
S
D
I
S
D
Y
Site 114
S907
R
S
Q
R
I
S
D
S
D
I
S
D
Y
E
V
Site 115
S910
R
I
S
D
S
D
I
S
D
Y
E
V
D
D
G
Site 116
Y912
S
D
S
D
I
S
D
Y
E
V
D
D
G
I
G
Site 117
S928
V
P
P
V
G
Y
R
S
S
A
R
E
S
K
S
Site 118
S929
P
P
V
G
Y
R
S
S
A
R
E
S
K
S
T
Site 119
S933
Y
R
S
S
A
R
E
S
K
S
T
T
L
T
V
Site 120
S935
S
S
A
R
E
S
K
S
T
T
L
T
V
P
E
Site 121
T936
S
A
R
E
S
K
S
T
T
L
T
V
P
E
Q
Site 122
T937
A
R
E
S
K
S
T
T
L
T
V
P
E
Q
Q
Site 123
T939
E
S
K
S
T
T
L
T
V
P
E
Q
Q
R
T
Site 124
T946
T
V
P
E
Q
Q
R
T
T
H
H
R
S
R
S
Site 125
T947
V
P
E
Q
Q
R
T
T
H
H
R
S
R
S
V
Site 126
S951
Q
R
T
T
H
H
R
S
R
S
V
S
P
H
R
Site 127
S953
T
T
H
H
R
S
R
S
V
S
P
H
R
G
N
Site 128
S955
H
H
R
S
R
S
V
S
P
H
R
G
N
D
Q
Site 129
S967
N
D
Q
G
K
P
R
S
R
L
P
N
V
P
L
Site 130
S977
P
N
V
P
L
Q
R
S
L
D
E
I
H
P
T
Site 131
T984
S
L
D
E
I
H
P
T
R
R
S
R
S
P
T
Site 132
S987
E
I
H
P
T
R
R
S
R
S
P
T
R
H
H
Site 133
S989
H
P
T
R
R
S
R
S
P
T
R
H
H
D
A
Site 134
T991
T
R
R
S
R
S
P
T
R
H
H
D
A
S
R
Site 135
S997
P
T
R
H
H
D
A
S
R
S
P
V
D
H
R
Site 136
S999
R
H
H
D
A
S
R
S
P
V
D
H
R
T
R
Site 137
T1005
R
S
P
V
D
H
R
T
R
D
V
D
S
Q
Y
Site 138
S1010
H
R
T
R
D
V
D
S
Q
Y
L
S
E
Q
D
Site 139
Y1012
T
R
D
V
D
S
Q
Y
L
S
E
Q
D
S
E
Site 140
S1014
D
V
D
S
Q
Y
L
S
E
Q
D
S
E
L
L
Site 141
S1018
Q
Y
L
S
E
Q
D
S
E
L
L
M
L
P
R
Site 142
S1031
P
R
A
K
R
G
R
S
A
E
C
L
H
T
T
Site 143
T1037
R
S
A
E
C
L
H
T
T
R
H
L
V
R
H
Site 144
Y1045
T
R
H
L
V
R
H
Y
K
T
L
P
P
K
M
Site 145
T1047
H
L
V
R
H
Y
K
T
L
P
P
K
M
P
L
Site 146
S1057
P
K
M
P
L
L
Q
S
S
S
H
W
N
I
Y
Site 147
S1059
M
P
L
L
Q
S
S
S
H
W
N
I
Y
S
S
Site 148
Y1064
S
S
S
H
W
N
I
Y
S
S
I
L
P
A
H
Site 149
S1065
S
S
H
W
N
I
Y
S
S
I
L
P
A
H
T
Site 150
S1066
S
H
W
N
I
Y
S
S
I
L
P
A
H
T
K
Site 151
T1072
S
S
I
L
P
A
H
T
K
T
K
S
V
T
R
Site 152
T1074
I
L
P
A
H
T
K
T
K
S
V
T
R
Q
D
Site 153
S1076
P
A
H
T
K
T
K
S
V
T
R
Q
D
I
S
Site 154
T1097
N
S
T
V
L
R
F
T
D
E
I
L
V
S
E
Site 155
S1114
P
F
L
D
R
A
R
S
A
S
T
N
C
L
R
Site 156
S1116
L
D
R
A
R
S
A
S
T
N
C
L
R
P
D
Site 157
T1124
T
N
C
L
R
P
D
T
S
L
H
S
P
E
R
Site 158
S1125
N
C
L
R
P
D
T
S
L
H
S
P
E
R
E
Site 159
S1128
R
P
D
T
S
L
H
S
P
E
R
E
R
G
R
Site 160
S1137
E
R
E
R
G
R
W
S
P
S
L
D
R
R
R
Site 161
S1139
E
R
G
R
W
S
P
S
L
D
R
R
R
P
P
Site 162
S1147
L
D
R
R
R
P
P
S
P
R
I
Q
I
Q
H
Site 163
S1156
R
I
Q
I
Q
H
A
S
P
E
N
D
R
H
S
Site 164
S1163
S
P
E
N
D
R
H
S
R
K
S
E
R
S
S
Site 165
S1166
N
D
R
H
S
R
K
S
E
R
S
S
I
Q
K
Site 166
S1169
H
S
R
K
S
E
R
S
S
I
Q
K
Q
T
R
Site 167
S1170
S
R
K
S
E
R
S
S
I
Q
K
Q
T
R
K
Site 168
T1179
Q
K
Q
T
R
K
G
T
A
S
D
A
E
R
V
Site 169
S1181
Q
T
R
K
G
T
A
S
D
A
E
R
V
L
P
Site 170
S1192
R
V
L
P
T
C
L
S
R
R
G
H
A
A
P
Site 171
T1202
G
H
A
A
P
R
A
T
D
Q
P
V
I
R
G
Site 172
S1215
R
G
K
H
P
A
R
S
R
S
S
E
H
S
S
Site 173
S1217
K
H
P
A
R
S
R
S
S
E
H
S
S
I
R
Site 174
S1218
H
P
A
R
S
R
S
S
E
H
S
S
I
R
T
Site 175
S1221
R
S
R
S
S
E
H
S
S
I
R
T
L
C
S
Site 176
S1222
S
R
S
S
E
H
S
S
I
R
T
L
C
S
M
Site 177
T1225
S
E
H
S
S
I
R
T
L
C
S
M
H
H
L
Site 178
S1241
P
G
G
S
A
P
P
S
P
L
L
T
R
M
H
Site 179
T1245
A
P
P
S
P
L
L
T
R
M
H
R
Q
R
S
Site 180
S1252
T
R
M
H
R
Q
R
S
P
T
Q
S
P
P
A
Site 181
T1254
M
H
R
Q
R
S
P
T
Q
S
P
P
A
D
T
Site 182
S1256
R
Q
R
S
P
T
Q
S
P
P
A
D
T
S
F
Site 183
T1261
T
Q
S
P
P
A
D
T
S
F
S
S
R
R
G
Site 184
S1262
Q
S
P
P
A
D
T
S
F
S
S
R
R
G
R
Site 185
S1264
P
P
A
D
T
S
F
S
S
R
R
G
R
Q
L
Site 186
S1265
P
A
D
T
S
F
S
S
R
R
G
R
Q
L
P
Site 187
S1278
L
P
Q
V
P
V
R
S
G
S
I
E
Q
A
S
Site 188
S1280
Q
V
P
V
R
S
G
S
I
E
Q
A
S
L
V
Site 189
S1285
S
G
S
I
E
Q
A
S
L
V
V
E
E
R
T
Site 190
T1306
V
H
R
F
K
Q
T
T
G
S
G
S
S
Q
E
Site 191
S1308
R
F
K
Q
T
T
G
S
G
S
S
Q
E
L
D
Site 192
Y1319
Q
E
L
D
R
E
Q
Y
S
K
Y
N
I
H
K
Site 193
Y1322
D
R
E
Q
Y
S
K
Y
N
I
H
K
D
Q
Y
Site 194
Y1329
Y
N
I
H
K
D
Q
Y
R
S
C
D
N
V
S
Site 195
S1336
Y
R
S
C
D
N
V
S
A
K
S
S
D
S
D
Site 196
S1339
C
D
N
V
S
A
K
S
S
D
S
D
V
S
D
Site 197
S1340
D
N
V
S
A
K
S
S
D
S
D
V
S
D
V
Site 198
S1342
V
S
A
K
S
S
D
S
D
V
S
D
V
S
A
Site 199
S1345
K
S
S
D
S
D
V
S
D
V
S
A
I
S
R
Site 200
S1348
D
S
D
V
S
D
V
S
A
I
S
R
T
S
S
Site 201
S1351
V
S
D
V
S
A
I
S
R
T
S
S
A
S
R
Site 202
T1353
D
V
S
A
I
S
R
T
S
S
A
S
R
L
S
Site 203
S1354
V
S
A
I
S
R
T
S
S
A
S
R
L
S
S
Site 204
S1355
S
A
I
S
R
T
S
S
A
S
R
L
S
S
T
Site 205
S1357
I
S
R
T
S
S
A
S
R
L
S
S
T
S
F
Site 206
S1360
T
S
S
A
S
R
L
S
S
T
S
F
M
S
E
Site 207
S1361
S
S
A
S
R
L
S
S
T
S
F
M
S
E
Q
Site 208
T1362
S
A
S
R
L
S
S
T
S
F
M
S
E
Q
S
Site 209
S1363
A
S
R
L
S
S
T
S
F
M
S
E
Q
S
E
Site 210
S1366
L
S
S
T
S
F
M
S
E
Q
S
E
R
P
R
Site 211
S1369
T
S
F
M
S
E
Q
S
E
R
P
R
G
R
I
Site 212
S1377
E
R
P
R
G
R
I
S
S
F
T
P
K
M
Q
Site 213
S1378
R
P
R
G
R
I
S
S
F
T
P
K
M
Q
G
Site 214
T1380
R
G
R
I
S
S
F
T
P
K
M
Q
G
R
R
Site 215
T1390
M
Q
G
R
R
M
G
T
S
G
R
S
I
M
K
Site 216
S1391
Q
G
R
R
M
G
T
S
G
R
S
I
M
K
S
Site 217
S1394
R
M
G
T
S
G
R
S
I
M
K
S
T
S
V
Site 218
S1398
S
G
R
S
I
M
K
S
T
S
V
S
G
E
M
Site 219
S1400
R
S
I
M
K
S
T
S
V
S
G
E
M
Y
T
Site 220
S1402
I
M
K
S
T
S
V
S
G
E
M
Y
T
L
E
Site 221
Y1406
T
S
V
S
G
E
M
Y
T
L
E
H
N
D
G
Site 222
T1407
S
V
S
G
E
M
Y
T
L
E
H
N
D
G
S
Site 223
S1414
T
L
E
H
N
D
G
S
Q
S
D
T
A
V
G
Site 224
S1416
E
H
N
D
G
S
Q
S
D
T
A
V
G
T
V
Site 225
T1418
N
D
G
S
Q
S
D
T
A
V
G
T
V
G
A
Site 226
T1422
Q
S
D
T
A
V
G
T
V
G
A
G
G
K
K
Site 227
S1432
A
G
G
K
K
R
R
S
S
L
S
A
K
V
V
Site 228
S1433
G
G
K
K
R
R
S
S
L
S
A
K
V
V
A
Site 229
S1435
K
K
R
R
S
S
L
S
A
K
V
V
A
I
V
Site 230
S1443
A
K
V
V
A
I
V
S
R
R
S
R
S
T
S
Site 231
S1446
V
A
I
V
S
R
R
S
R
S
T
S
Q
L
S
Site 232
S1448
I
V
S
R
R
S
R
S
T
S
Q
L
S
Q
T
Site 233
T1449
V
S
R
R
S
R
S
T
S
Q
L
S
Q
T
E
Site 234
S1450
S
R
R
S
R
S
T
S
Q
L
S
Q
T
E
S
Site 235
S1453
S
R
S
T
S
Q
L
S
Q
T
E
S
G
H
K
Site 236
T1455
S
T
S
Q
L
S
Q
T
E
S
G
H
K
K
L
Site 237
S1457
S
Q
L
S
Q
T
E
S
G
H
K
K
L
K
S
Site 238
S1464
S
G
H
K
K
L
K
S
T
I
Q
R
S
T
E
Site 239
T1465
G
H
K
K
L
K
S
T
I
Q
R
S
T
E
T
Site 240
T1470
K
S
T
I
Q
R
S
T
E
T
G
M
A
A
E
Site 241
S1486
R
K
M
V
R
Q
P
S
R
E
S
T
D
G
S
Site 242
S1489
V
R
Q
P
S
R
E
S
T
D
G
S
I
N
S
Site 243
T1490
R
Q
P
S
R
E
S
T
D
G
S
I
N
S
Y
Site 244
S1493
S
R
E
S
T
D
G
S
I
N
S
Y
S
S
E
Site 245
S1496
S
T
D
G
S
I
N
S
Y
S
S
E
G
N
L
Site 246
Y1497
T
D
G
S
I
N
S
Y
S
S
E
G
N
L
I
Site 247
S1498
D
G
S
I
N
S
Y
S
S
E
G
N
L
I
F
Site 248
S1499
G
S
I
N
S
Y
S
S
E
G
N
L
I
F
P
Site 249
S1514
G
V
R
L
G
A
D
S
Q
F
S
D
F
L
D
Site 250
S1517
L
G
A
D
S
Q
F
S
D
F
L
D
G
L
G
Site 251
T1536
V
G
R
Q
T
L
A
T
P
A
M
G
D
I
Q
Site 252
S1562
V
E
V
I
R
A
R
S
L
T
Q
K
P
G
S
Site 253
T1564
V
I
R
A
R
S
L
T
Q
K
P
G
S
K
S
Site 254
S1569
S
L
T
Q
K
P
G
S
K
S
T
P
A
P
Y
Site 255
S1571
T
Q
K
P
G
S
K
S
T
P
A
P
Y
V
K
Site 256
T1572
Q
K
P
G
S
K
S
T
P
A
P
Y
V
K
V
Site 257
Y1576
S
K
S
T
P
A
P
Y
V
K
V
Y
L
L
E
Site 258
Y1580
P
A
P
Y
V
K
V
Y
L
L
E
N
G
A
C
Site 259
T1599
K
T
R
I
A
R
K
T
L
D
P
L
Y
Q
Q
Site 260
Y1604
R
K
T
L
D
P
L
Y
Q
Q
S
L
V
F
D
Site 261
S1607
L
D
P
L
Y
Q
Q
S
L
V
F
D
E
S
P
Site 262
S1613
Q
S
L
V
F
D
E
S
P
Q
G
K
V
L
Q
Site 263
Y1627
Q
V
I
V
W
G
D
Y
G
R
M
D
H
K
C
Site 264
S1662
W
Y
K
L
F
P
P
S
S
L
V
D
P
T
L
Site 265
S1663
Y
K
L
F
P
P
S
S
L
V
D
P
T
L
T
Site 266
T1668
P
S
S
L
V
D
P
T
L
T
P
L
T
R
R
Site 267
T1670
S
L
V
D
P
T
L
T
P
L
T
R
R
A
S
Site 268
T1673
D
P
T
L
T
P
L
T
R
R
A
S
Q
S
S
Site 269
S1677
T
P
L
T
R
R
A
S
Q
S
S
L
E
S
S
Site 270
S1679
L
T
R
R
A
S
Q
S
S
L
E
S
S
T
G
Site 271
S1680
T
R
R
A
S
Q
S
S
L
E
S
S
T
G
P
Site 272
S1683
A
S
Q
S
S
L
E
S
S
T
G
P
P
C
I
Site 273
S1684
S
Q
S
S
L
E
S
S
T
G
P
P
C
I
R
Site 274
S1692
T
G
P
P
C
I
R
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation