KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
URP2
Full Name:
Fermitin family homolog 3
Alias:
Fermitin family 3; KIND3; Kindlin-3; MGC10966; MIG-2; MIG2B; MIG2-like; Unc-112 related protein 2; UNC112C
Type:
Adhesion
Mass (Da):
75953
Number AA:
667
UniProt ID:
Q86UX7
International Prot ID:
IPI00397834
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005886
GO:0002102
Uniprot
OncoNet
Molecular Function:
GO:0005178
PhosphoSite+
KinaseNET
Biological Process:
GO:0033622
GO:0007159
GO:0070527
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
A
G
M
K
T
A
S
G
D
Y
I
D
Site 2
S8
M
A
G
M
K
T
A
S
G
D
Y
I
D
S
S
Site 3
Y11
M
K
T
A
S
G
D
Y
I
D
S
S
W
E
L
Site 4
S14
A
S
G
D
Y
I
D
S
S
W
E
L
R
V
F
Site 5
S15
S
G
D
Y
I
D
S
S
W
E
L
R
V
F
V
Site 6
S31
E
E
D
P
E
A
E
S
V
T
L
R
V
T
G
Site 7
T37
E
S
V
T
L
R
V
T
G
E
S
H
I
G
G
Site 8
Y83
T
H
W
T
L
D
K
Y
G
I
L
A
D
A
R
Site 9
S115
R
A
L
R
L
R
A
S
F
S
Q
P
L
F
Q
Site 10
S140
I
R
H
P
E
E
L
S
L
L
R
A
P
E
K
Site 11
Y162
K
E
P
E
E
E
L
Y
D
L
S
K
V
V
L
Site 12
S165
E
E
E
L
Y
D
L
S
K
V
V
L
A
G
G
Site 13
S186
R
G
M
P
A
H
F
S
D
S
A
Q
T
E
A
Site 14
Y195
S
A
Q
T
E
A
C
Y
H
M
L
S
R
P
Q
Site 15
S199
E
A
C
Y
H
M
L
S
R
P
Q
P
P
P
D
Site 16
S217
L
Q
R
L
P
R
P
S
S
L
S
D
K
T
Q
Site 17
S218
Q
R
L
P
R
P
S
S
L
S
D
K
T
Q
L
Site 18
S220
L
P
R
P
S
S
L
S
D
K
T
Q
L
H
S
Site 19
T223
P
S
S
L
S
D
K
T
Q
L
H
S
R
W
L
Site 20
Y254
L
W
L
R
F
K
Y
Y
S
F
F
D
L
D
P
Site 21
T263
F
F
D
L
D
P
K
T
D
P
V
R
L
T
Q
Site 22
T269
K
T
D
P
V
R
L
T
Q
L
Y
E
Q
A
R
Site 23
Y272
P
V
R
L
T
Q
L
Y
E
Q
A
R
W
D
L
Site 24
S305
Q
Y
H
I
N
K
L
S
Q
S
G
E
V
G
E
Site 25
T316
E
V
G
E
P
A
G
T
D
P
G
L
D
D
L
Site 26
T347
T
D
V
L
D
S
L
T
T
I
P
E
L
K
D
Site 27
T369
P
R
R
P
R
K
L
T
L
K
G
Y
R
Q
H
Site 28
Y373
R
K
L
T
L
K
G
Y
R
Q
H
W
V
V
F
Site 29
S386
V
F
K
E
T
T
L
S
Y
Y
K
S
Q
D
E
Site 30
S390
T
T
L
S
Y
Y
K
S
Q
D
E
A
P
G
D
Site 31
S428
C
I
K
L
L
V
P
S
P
E
G
M
S
E
I
Site 32
Y436
P
E
G
M
S
E
I
Y
L
R
C
Q
D
E
Q
Site 33
S456
M
A
G
C
R
L
A
S
K
G
R
T
M
A
D
Site 34
T460
R
L
A
S
K
G
R
T
M
A
D
S
S
Y
T
Site 35
S464
K
G
R
T
M
A
D
S
S
Y
T
S
E
V
Q
Site 36
S465
G
R
T
M
A
D
S
S
Y
T
S
E
V
Q
A
Site 37
Y466
R
T
M
A
D
S
S
Y
T
S
E
V
Q
A
I
Site 38
T482
A
F
L
S
L
Q
R
T
G
S
G
G
P
G
N
Site 39
S484
L
S
L
Q
R
T
G
S
G
G
P
G
N
H
P
Site 40
S497
H
P
H
G
P
D
A
S
A
E
G
L
N
P
Y
Site 41
Y504
S
A
E
G
L
N
P
Y
G
L
V
A
P
R
F
Site 42
T521
K
F
K
A
K
Q
L
T
P
R
I
L
E
A
H
Site 43
S535
H
Q
N
V
A
Q
L
S
L
A
E
A
Q
L
R
Site 44
S549
R
F
I
Q
A
W
Q
S
L
P
D
F
G
I
S
Site 45
T591
A
V
G
D
V
V
K
T
W
R
F
S
N
M
R
Site 46
S622
E
H
I
N
V
A
F
S
C
V
S
A
S
C
R
Site 47
S625
N
V
A
F
S
C
V
S
A
S
C
R
I
V
H
Site 48
S642
I
G
G
Y
I
F
L
S
T
R
E
R
A
R
G
Site 49
T661
E
D
L
F
L
Q
L
T
G
G
H
E
A
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation