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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR180
Full Name:
Integral membrane protein GPR180
Alias:
Intimal thickness-related receptor
Type:
Mass (Da):
49395
Number AA:
440
UniProt ID:
Q86V85
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
P
Q
G
S
Q
G
K
T
L
R
G
S
F
S
S
Site 2
S28
Q
G
K
T
L
R
G
S
F
S
S
T
A
A
Q
Site 3
S30
K
T
L
R
G
S
F
S
S
T
A
A
Q
D
A
Site 4
S31
T
L
R
G
S
F
S
S
T
A
A
Q
D
A
Q
Site 5
T32
L
R
G
S
F
S
S
T
A
A
Q
D
A
Q
G
Site 6
Y72
V
G
K
E
A
K
L
Y
L
F
Q
A
Q
E
W
Site 7
S85
E
W
L
K
L
Q
Q
S
S
H
G
Y
S
C
S
Site 8
S86
W
L
K
L
Q
Q
S
S
H
G
Y
S
C
S
E
Site 9
S90
Q
Q
S
S
H
G
Y
S
C
S
E
K
L
S
K
Site 10
S92
S
S
H
G
Y
S
C
S
E
K
L
S
K
A
Q
Site 11
S96
Y
S
C
S
E
K
L
S
K
A
Q
L
T
M
T
Site 12
T103
S
K
A
Q
L
T
M
T
M
N
Q
T
E
H
N
Site 13
T112
N
Q
T
E
H
N
L
T
V
S
Q
I
P
S
P
Site 14
S114
T
E
H
N
L
T
V
S
Q
I
P
S
P
Q
T
Site 15
T121
S
Q
I
P
S
P
Q
T
W
H
V
F
Y
A
D
Site 16
Y130
H
V
F
Y
A
D
K
Y
T
C
Q
D
D
K
E
Site 17
S139
C
Q
D
D
K
E
N
S
Q
V
E
D
I
P
F
Site 18
S164
G
N
P
F
D
H
F
S
A
G
E
S
G
L
H
Site 19
S168
D
H
F
S
A
G
E
S
G
L
H
E
F
F
F
Site 20
Y224
A
G
S
A
L
A
N
Y
I
H
F
S
S
Y
S
Site 21
S229
A
N
Y
I
H
F
S
S
Y
S
K
D
G
I
G
Site 22
Y230
N
Y
I
H
F
S
S
Y
S
K
D
G
I
G
V
Site 23
S231
Y
I
H
F
S
S
Y
S
K
D
G
I
G
V
P
Site 24
S274
T
I
V
R
M
K
K
S
Q
S
R
P
L
Q
W
Site 25
S276
V
R
M
K
K
S
Q
S
R
P
L
Q
W
D
S
Site 26
S283
S
R
P
L
Q
W
D
S
T
P
A
S
T
G
I
Site 27
T284
R
P
L
Q
W
D
S
T
P
A
S
T
G
I
A
Site 28
Y315
E
D
I
S
H
H
S
Y
H
S
H
H
N
L
A
Site 29
T351
I
I
T
V
E
R
S
T
L
K
R
E
F
Y
I
Site 30
Y357
S
T
L
K
R
E
F
Y
I
T
F
A
K
G
C
Site 31
S413
Y
R
L
F
L
S
H
S
L
Y
W
E
V
S
S
Site 32
T429
S
S
V
T
L
P
L
T
I
S
S
G
H
K
S
Site 33
S431
V
T
L
P
L
T
I
S
S
G
H
K
S
R
P
Site 34
S432
T
L
P
L
T
I
S
S
G
H
K
S
R
P
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation