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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAPTM4B
Full Name:
Lysosomal-associated transmembrane protein 4B
Alias:
LAP4B; LAPTM4beta; LC27; Lysosomal-associated transmembrane 4B
Type:
Transport protein, endomembrane. LAPTM4/LAPTM5 transporter family.
Mass (Da):
41146
Number AA:
370
UniProt ID:
Q86VI4
International Prot ID:
Isoform1 - IPI00465172
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0012505
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
D
E
R
R
K
A
R
T
S
T
Q
G
R
L
G
Site 2
S16
E
R
R
K
A
R
T
S
T
Q
G
R
L
G
D
Site 3
T17
R
R
K
A
R
T
S
T
Q
G
R
L
G
D
W
Site 4
T33
R
V
H
A
D
G
F
T
H
R
V
L
G
A
P
Site 5
S45
G
A
P
A
A
A
W
S
S
S
S
W
L
E
P
Site 6
S47
P
A
A
A
W
S
S
S
S
W
L
E
P
A
M
Site 7
T55
S
W
L
E
P
A
M
T
S
R
T
R
V
T
W
Site 8
T61
M
T
S
R
T
R
V
T
W
P
S
P
P
R
P
Site 9
S64
R
T
R
V
T
W
P
S
P
P
R
P
L
P
V
Site 10
S91
T
D
P
A
E
A
R
S
S
R
G
I
E
E
A
Site 11
S92
D
P
A
E
A
R
S
S
R
G
I
E
E
A
G
Site 12
S115
R
E
P
E
R
R
R
S
R
Q
Q
R
R
G
G
Site 13
S128
G
G
L
Q
A
R
R
S
T
L
L
K
T
C
A
Site 14
T129
G
L
Q
A
R
R
S
T
L
L
K
T
C
A
R
Site 15
T133
R
R
S
T
L
L
K
T
C
A
R
A
R
A
T
Site 16
T140
T
C
A
R
A
R
A
T
A
P
G
A
M
K
M
Site 17
Y197
A
L
A
D
P
D
Q
Y
N
F
S
S
S
E
L
Site 18
S200
D
P
D
Q
Y
N
F
S
S
S
E
L
G
G
D
Site 19
S202
D
Q
Y
N
F
S
S
S
E
L
G
G
D
F
E
Site 20
S272
T
V
L
I
Y
P
N
S
I
Q
E
Y
I
R
Q
Site 21
Y276
Y
P
N
S
I
Q
E
Y
I
R
Q
L
P
P
N
Site 22
S292
P
Y
R
D
D
V
M
S
V
N
P
T
C
L
V
Site 23
S332
R
Y
I
N
G
R
N
S
S
D
V
L
V
Y
V
Site 24
S333
Y
I
N
G
R
N
S
S
D
V
L
V
Y
V
T
Site 25
Y338
N
S
S
D
V
L
V
Y
V
T
S
N
D
T
T
Site 26
T345
Y
V
T
S
N
D
T
T
V
L
L
P
P
Y
D
Site 27
Y351
T
T
V
L
L
P
P
Y
D
D
A
T
V
N
G
Site 28
T355
L
P
P
Y
D
D
A
T
V
N
G
A
A
K
E
Site 29
Y367
A
K
E
P
P
P
P
Y
V
S
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation