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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC47A2
Full Name:
Multidrug and toxin extrusion protein 2
Alias:
Kidney-specific H(+)/organic cation antiporter;Solute carrier family 47 member 2
Type:
Mass (Da):
65085
Number AA:
602
UniProt ID:
Q86VL8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
D
S
L
Q
D
T
V
A
L
D
H
G
G
Site 2
S97
S
A
C
D
T
L
M
S
Q
S
F
G
S
P
N
Site 3
S99
C
D
T
L
M
S
Q
S
F
G
S
P
N
K
K
Site 4
S102
L
M
S
Q
S
F
G
S
P
N
K
K
H
V
G
Site 5
T150
D
P
D
V
S
R
L
T
Q
D
Y
V
M
I
F
Site 6
Y173
L
Y
N
L
L
A
K
Y
L
Q
N
Q
G
W
L
Site 7
S187
L
K
G
Q
E
E
E
S
P
F
Q
T
P
G
L
Site 8
T191
E
E
E
S
P
F
Q
T
P
G
L
S
I
L
H
Site 9
S195
P
F
Q
T
P
G
L
S
I
L
H
P
S
H
S
Site 10
S200
G
L
S
I
L
H
P
S
H
S
H
L
S
R
A
Site 11
S202
S
I
L
H
P
S
H
S
H
L
S
R
A
S
F
Site 12
S205
H
P
S
H
S
H
L
S
R
A
S
F
H
L
F
Site 13
S208
H
S
H
L
S
R
A
S
F
H
L
F
Q
K
I
Site 14
T276
L
K
K
L
H
L
E
T
W
A
G
W
S
S
Q
Site 15
T434
Y
G
G
V
L
R
G
T
G
K
Q
A
F
G
A
Site 16
S505
A
E
E
A
K
K
H
S
G
R
Q
Q
Q
Q
R
Site 17
S515
Q
Q
Q
Q
R
A
E
S
T
A
T
R
P
G
P
Site 18
S528
G
P
E
K
A
V
L
S
S
V
A
T
G
S
S
Site 19
S529
P
E
K
A
V
L
S
S
V
A
T
G
S
S
P
Site 20
T539
T
G
S
S
P
G
I
T
L
T
T
Y
S
R
S
Site 21
T541
S
S
P
G
I
T
L
T
T
Y
S
R
S
E
C
Site 22
T542
S
P
G
I
T
L
T
T
Y
S
R
S
E
C
H
Site 23
Y543
P
G
I
T
L
T
T
Y
S
R
S
E
C
H
V
Site 24
S544
G
I
T
L
T
T
Y
S
R
S
E
C
H
V
D
Site 25
T555
C
H
V
D
F
F
R
T
P
E
E
A
H
A
L
Site 26
S563
P
E
E
A
H
A
L
S
A
P
T
S
R
L
S
Site 27
S567
H
A
L
S
A
P
T
S
R
L
S
V
K
Q
L
Site 28
S570
S
A
P
T
S
R
L
S
V
K
Q
L
V
I
R
Site 29
S586
G
A
A
L
G
A
A
S
A
T
L
M
V
G
L
Site 30
T588
A
L
G
A
A
S
A
T
L
M
V
G
L
T
V
Site 31
T594
A
T
L
M
V
G
L
T
V
R
I
L
A
T
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation