KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
C6orf152
Full Name:
Lebercilin
Alias:
CF152; Leber congenital amaurosis 5; Lebercilin
Type:
Unknown function
Mass (Da):
80554
Number AA:
697
UniProt ID:
Q86VQ0
International Prot ID:
IPI00334013
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0035085
GO:0005932
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
E
R
A
G
S
P
G
T
D
Q
E
R
Site 2
Y21
R
K
A
G
K
H
H
Y
S
Y
L
S
D
F
E
Site 3
Y23
A
G
K
H
H
Y
S
Y
L
S
D
F
E
T
P
Site 4
S25
K
H
H
Y
S
Y
L
S
D
F
E
T
P
Q
S
Site 5
T29
S
Y
L
S
D
F
E
T
P
Q
S
S
G
R
S
Site 6
S32
S
D
F
E
T
P
Q
S
S
G
R
S
S
L
V
Site 7
S33
D
F
E
T
P
Q
S
S
G
R
S
S
L
V
S
Site 8
S36
T
P
Q
S
S
G
R
S
S
L
V
S
S
S
P
Site 9
S37
P
Q
S
S
G
R
S
S
L
V
S
S
S
P
A
Site 10
S40
S
G
R
S
S
L
V
S
S
S
P
A
S
V
R
Site 11
S41
G
R
S
S
L
V
S
S
S
P
A
S
V
R
R
Site 12
S42
R
S
S
L
V
S
S
S
P
A
S
V
R
R
K
Site 13
S45
L
V
S
S
S
P
A
S
V
R
R
K
N
P
K
Site 14
T55
R
K
N
P
K
R
Q
T
S
D
G
Q
V
H
H
Site 15
S56
K
N
P
K
R
Q
T
S
D
G
Q
V
H
H
Q
Site 16
S69
H
Q
A
P
R
K
P
S
P
K
G
L
P
N
R
Site 17
S85
G
V
R
V
G
F
R
S
Q
S
L
N
R
E
P
Site 18
S87
R
V
G
F
R
S
Q
S
L
N
R
E
P
L
R
Site 19
T97
R
E
P
L
R
K
D
T
D
L
V
T
K
R
I
Site 20
T101
R
K
D
T
D
L
V
T
K
R
I
L
S
A
R
Site 21
S135
E
L
L
K
E
N
K
S
L
K
R
L
Q
Y
R
Site 22
Y141
K
S
L
K
R
L
Q
Y
R
Q
E
K
A
L
N
Site 23
S158
E
D
A
E
N
E
I
S
Q
L
I
F
R
H
N
Site 24
S178
L
K
E
R
L
R
K
S
Q
E
K
E
R
A
T
Site 25
T185
S
Q
E
K
E
R
A
T
E
K
R
V
K
D
T
Site 26
S194
K
R
V
K
D
T
E
S
E
L
F
R
T
K
F
Site 27
T199
T
E
S
E
L
F
R
T
K
F
S
L
Q
K
L
Site 28
S202
E
L
F
R
T
K
F
S
L
Q
K
L
K
E
I
Site 29
S210
L
Q
K
L
K
E
I
S
E
A
R
H
L
P
E
Site 30
T235
A
E
L
K
L
D
D
T
E
R
R
I
K
E
L
Site 31
S243
E
R
R
I
K
E
L
S
K
N
L
E
L
S
T
Site 32
S249
L
S
K
N
L
E
L
S
T
N
S
F
Q
R
Q
Site 33
S252
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Site 34
Y265
L
A
E
R
K
R
A
Y
E
A
H
D
E
N
K
Site 35
Y282
Q
K
E
V
Q
R
L
Y
H
K
L
K
E
K
E
Site 36
Y298
E
L
D
I
K
N
I
Y
S
N
R
L
P
K
S
Site 37
S299
L
D
I
K
N
I
Y
S
N
R
L
P
K
S
S
Site 38
S305
Y
S
N
R
L
P
K
S
S
P
N
K
E
K
E
Site 39
S306
S
N
R
L
P
K
S
S
P
N
K
E
K
E
L
Site 40
T330
S
D
F
A
D
L
C
T
K
G
V
Q
T
M
E
Site 41
Y344
E
D
F
K
P
E
E
Y
P
L
T
P
E
T
I
Site 42
T347
K
P
E
E
Y
P
L
T
P
E
T
I
M
C
Y
Site 43
Y354
T
P
E
T
I
M
C
Y
E
N
K
W
E
E
P
Site 44
T365
W
E
E
P
G
H
L
T
L
D
L
Q
S
Q
K
Site 45
S370
H
L
T
L
D
L
Q
S
Q
K
Q
D
R
H
G
Site 46
T394
E
R
E
E
K
F
V
T
D
E
E
L
H
V
V
Site 47
S426
K
K
Q
K
E
K
A
S
L
L
E
R
E
E
K
Site 48
Y441
P
E
W
E
T
G
R
Y
Q
L
G
M
Y
P
I
Site 49
Y446
G
R
Y
Q
L
G
M
Y
P
I
Q
N
M
D
K
Site 50
S481
I
D
R
E
L
Q
D
S
R
N
L
K
Y
P
V
Site 51
Y486
Q
D
S
R
N
L
K
Y
P
V
L
P
L
L
P
Site 52
S497
P
L
L
P
D
F
E
S
K
L
H
S
P
E
R
Site 53
S501
D
F
E
S
K
L
H
S
P
E
R
S
P
K
T
Site 54
S505
K
L
H
S
P
E
R
S
P
K
T
Y
R
F
S
Site 55
T508
S
P
E
R
S
P
K
T
Y
R
F
S
E
S
S
Site 56
Y509
P
E
R
S
P
K
T
Y
R
F
S
E
S
S
E
Site 57
S512
S
P
K
T
Y
R
F
S
E
S
S
E
R
L
F
Site 58
S514
K
T
Y
R
F
S
E
S
S
E
R
L
F
N
G
Site 59
S515
T
Y
R
F
S
E
S
S
E
R
L
F
N
G
H
Site 60
S528
G
H
H
L
Q
D
I
S
F
S
T
P
K
G
E
Site 61
S530
H
L
Q
D
I
S
F
S
T
P
K
G
E
G
Q
Site 62
T531
L
Q
D
I
S
F
S
T
P
K
G
E
G
Q
N
Site 63
S539
P
K
G
E
G
Q
N
S
G
N
V
R
S
P
A
Site 64
S544
Q
N
S
G
N
V
R
S
P
A
S
P
N
E
F
Site 65
S547
G
N
V
R
S
P
A
S
P
N
E
F
A
F
G
Site 66
S555
P
N
E
F
A
F
G
S
Y
V
P
S
F
A
K
Site 67
Y556
N
E
F
A
F
G
S
Y
V
P
S
F
A
K
T
Site 68
S559
A
F
G
S
Y
V
P
S
F
A
K
T
S
E
R
Site 69
T563
Y
V
P
S
F
A
K
T
S
E
R
S
N
P
F
Site 70
S564
V
P
S
F
A
K
T
S
E
R
S
N
P
F
S
Site 71
S571
S
E
R
S
N
P
F
S
Q
K
S
S
F
L
D
Site 72
S575
N
P
F
S
Q
K
S
S
F
L
D
F
Q
R
N
Site 73
S583
F
L
D
F
Q
R
N
S
M
E
K
L
S
K
D
Site 74
S612
M
E
Q
L
F
G
A
S
G
S
S
T
I
S
S
Site 75
S614
Q
L
F
G
A
S
G
S
S
T
I
S
S
K
S
Site 76
S615
L
F
G
A
S
G
S
S
T
I
S
S
K
S
S
Site 77
T616
F
G
A
S
G
S
S
T
I
S
S
K
S
S
D
Site 78
S618
A
S
G
S
S
T
I
S
S
K
S
S
D
P
N
Site 79
S619
S
G
S
S
T
I
S
S
K
S
S
D
P
N
S
Site 80
S621
S
S
T
I
S
S
K
S
S
D
P
N
S
V
A
Site 81
S622
S
T
I
S
S
K
S
S
D
P
N
S
V
A
S
Site 82
S626
S
K
S
S
D
P
N
S
V
A
S
S
K
G
D
Site 83
S630
D
P
N
S
V
A
S
S
K
G
D
I
D
P
L
Site 84
S660
E
D
E
G
F
F
L
S
E
G
R
S
F
N
P
Site 85
S664
F
F
L
S
E
G
R
S
F
N
P
N
R
H
R
Site 86
S686
P
A
V
K
A
A
D
S
V
E
D
E
I
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation