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Updated November 2019
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Protein Info
Short Name:
FAM134C
Full Name:
Protein FAM134C
Alias:
DKFZp686B1036; F134C; family with sequence similarity 134, member C; FLJ33806
Type:
Unknown function
Mass (Da):
51396
Number AA:
466
UniProt ID:
Q86VR2
International Prot ID:
IPI00254338
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
E
A
E
G
V
P
T
T
P
G
P
A
S
G
Site 2
T10
E
A
E
G
V
P
T
T
P
G
P
A
S
G
S
Site 3
S15
P
T
T
P
G
P
A
S
G
S
T
F
R
G
R
Site 4
S17
T
P
G
P
A
S
G
S
T
F
R
G
R
R
D
Site 5
T18
P
G
P
A
S
G
S
T
F
R
G
R
R
D
V
Site 6
S26
F
R
G
R
R
D
V
S
G
S
W
E
R
D
Q
Site 7
S28
G
R
R
D
V
S
G
S
W
E
R
D
Q
Q
V
Site 8
Y49
L
V
E
V
L
G
P
Y
E
P
L
L
S
R
V
Site 9
S126
P
D
A
L
D
N
E
S
W
G
F
V
H
P
R
Site 10
Y216
H
R
L
W
D
R
A
Y
V
R
L
K
P
A
L
Site 11
S229
A
L
Q
R
L
D
F
S
V
R
G
Y
M
M
S
Site 12
Y233
L
D
F
S
V
R
G
Y
M
M
S
K
Q
R
E
Site 13
S236
S
V
R
G
Y
M
M
S
K
Q
R
E
R
Q
L
Site 14
S258
E
R
A
M
D
N
H
S
D
S
E
E
E
L
A
Site 15
S260
A
M
D
N
H
S
D
S
E
E
E
L
A
A
F
Site 16
S274
F
C
P
Q
L
D
D
S
T
V
A
R
E
L
A
Site 17
T275
C
P
Q
L
D
D
S
T
V
A
R
E
L
A
I
Site 18
T283
V
A
R
E
L
A
I
T
D
S
E
H
S
D
A
Site 19
S285
R
E
L
A
I
T
D
S
E
H
S
D
A
E
V
Site 20
S288
A
I
T
D
S
E
H
S
D
A
E
V
S
C
T
Site 21
S293
E
H
S
D
A
E
V
S
C
T
D
N
G
T
F
Site 22
T295
S
D
A
E
V
S
C
T
D
N
G
T
F
N
L
Site 23
T299
V
S
C
T
D
N
G
T
F
N
L
S
R
G
Q
Site 24
S303
D
N
G
T
F
N
L
S
R
G
Q
T
P
L
T
Site 25
T307
F
N
L
S
R
G
Q
T
P
L
T
E
G
S
E
Site 26
T310
S
R
G
Q
T
P
L
T
E
G
S
E
D
L
D
Site 27
S313
Q
T
P
L
T
E
G
S
E
D
L
D
G
H
S
Site 28
S320
S
E
D
L
D
G
H
S
D
P
E
E
S
F
A
Site 29
S325
G
H
S
D
P
E
E
S
F
A
R
D
L
P
D
Site 30
S335
R
D
L
P
D
F
P
S
I
N
M
D
P
A
G
Site 31
T349
G
L
D
D
E
D
D
T
S
I
G
M
P
S
L
Site 32
S350
L
D
D
E
D
D
T
S
I
G
M
P
S
L
M
Site 33
S355
D
T
S
I
G
M
P
S
L
M
Y
R
S
P
P
Site 34
Y358
I
G
M
P
S
L
M
Y
R
S
P
P
G
A
E
Site 35
S360
M
P
S
L
M
Y
R
S
P
P
G
A
E
E
P
Site 36
S419
G
A
S
Q
P
G
P
S
G
A
P
A
Q
R
A
Site 37
T427
G
A
P
A
Q
R
A
T
R
G
F
L
R
S
P
Site 38
S433
A
T
R
G
F
L
R
S
P
S
S
D
L
D
T
Site 39
S435
R
G
F
L
R
S
P
S
S
D
L
D
T
D
A
Site 40
S436
G
F
L
R
S
P
S
S
D
L
D
T
D
A
E
Site 41
T440
S
P
S
S
D
L
D
T
D
A
E
G
D
D
F
Site 42
S453
D
F
E
L
L
D
Q
S
E
L
S
Q
L
D
P
Site 43
S456
L
L
D
Q
S
E
L
S
Q
L
D
P
A
S
S
Site 44
S462
L
S
Q
L
D
P
A
S
S
R
S
H
_
_
_
Site 45
S463
S
Q
L
D
P
A
S
S
R
S
H
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation