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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSPYL5
Full Name:
Testis-specific Y-encoded-like protein 5
Alias:
TSPY-like 5; TSYL5
Type:
Mass (Da):
45143
Number AA:
417
UniProt ID:
Q86VY4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006334
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
G
R
S
R
G
R
K
S
S
R
Site 2
S10
G
R
S
R
G
R
K
S
S
R
A
K
N
R
G
Site 3
S11
R
S
R
G
R
K
S
S
R
A
K
N
R
G
K
Site 4
S39
A
P
R
D
P
D
P
S
Q
Y
Q
S
L
G
E
Site 5
Y41
R
D
P
D
P
S
Q
Y
Q
S
L
G
E
D
T
Site 6
S43
P
D
P
S
Q
Y
Q
S
L
G
E
D
T
Q
A
Site 7
S111
P
G
P
G
K
A
A
S
L
S
E
R
L
A
A
Site 8
S113
P
G
K
A
A
S
L
S
E
R
L
A
A
D
T
Site 9
T120
S
E
R
L
A
A
D
T
V
F
V
G
T
A
G
Site 10
T152
A
G
K
K
A
P
E
T
C
S
T
A
G
R
G
Site 11
T155
K
A
P
E
T
C
S
T
A
G
R
G
P
Q
V
Site 12
S178
G
A
A
G
E
N
T
S
V
S
A
G
E
E
K
Site 13
S180
A
G
E
N
T
S
V
S
A
G
E
E
K
K
E
Site 14
S193
K
E
E
R
D
A
G
S
G
P
P
A
T
E
G
Site 15
T198
A
G
S
G
P
P
A
T
E
G
S
M
D
T
L
Site 16
S201
G
P
P
A
T
E
G
S
M
D
T
L
E
N
V
Site 17
T204
A
T
E
G
S
M
D
T
L
E
N
V
Q
L
K
Site 18
Y223
N
A
Q
A
D
R
A
Y
L
R
L
S
R
K
F
Site 19
S227
D
R
A
Y
L
R
L
S
R
K
F
G
Q
L
R
Site 20
S264
Q
N
H
P
Q
L
A
S
F
L
N
S
Q
E
K
Site 21
S268
Q
L
A
S
F
L
N
S
Q
E
K
E
V
L
S
Site 22
S275
S
Q
E
K
E
V
L
S
Y
L
N
S
L
E
V
Site 23
Y276
Q
E
K
E
V
L
S
Y
L
N
S
L
E
V
E
Site 24
Y297
L
G
Y
K
I
K
F
Y
F
D
R
N
P
Y
F
Site 25
Y303
F
Y
F
D
R
N
P
Y
F
Q
N
K
V
L
I
Site 26
Y313
N
K
V
L
I
K
E
Y
G
C
G
P
S
G
Q
Site 27
S318
K
E
Y
G
C
G
P
S
G
Q
V
V
S
R
S
Site 28
S323
G
P
S
G
Q
V
V
S
R
S
T
P
I
Q
W
Site 29
S325
S
G
Q
V
V
S
R
S
T
P
I
Q
W
L
P
Site 30
T326
G
Q
V
V
S
R
S
T
P
I
Q
W
L
P
G
Site 31
S338
L
P
G
H
D
L
Q
S
L
S
Q
G
N
P
E
Site 32
S340
G
H
D
L
Q
S
L
S
Q
G
N
P
E
N
N
Site 33
S355
R
S
F
F
G
W
F
S
N
H
S
S
I
E
S
Site 34
S359
G
W
F
S
N
H
S
S
I
E
S
D
K
I
V
Site 35
S362
S
N
H
S
S
I
E
S
D
K
I
V
E
I
I
Site 36
Y381
W
P
N
P
L
Q
F
Y
L
L
S
E
G
A
R
Site 37
S384
P
L
Q
F
Y
L
L
S
E
G
A
R
V
E
K
Site 38
T408
P
G
K
Q
P
M
E
T
T
Q
P
G
V
S
Q
Site 39
T409
G
K
Q
P
M
E
T
T
Q
P
G
V
S
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation