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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
P2RY8
Full Name:
P2Y purinoceptor 8
Alias:
G-protein coupled purinergic receptor P2Y8; P2Y8; purinergic receptor P2Y, G-protein coupled, 8
Type:
Receptor, GPCR
Mass (Da):
40635
Number AA:
359
UniProt ID:
Q86VZ1
International Prot ID:
IPI00329027
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0045028
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
S
T
G
P
D
N
A
T
L
Q
M
L
R
N
P
Site 2
Y127
E
R
F
L
G
V
L
Y
P
L
S
S
K
R
W
Site 3
S130
L
G
V
L
Y
P
L
S
S
K
R
W
R
R
R
Site 4
S131
G
V
L
Y
P
L
S
S
K
R
W
R
R
R
R
Site 5
Y139
K
R
W
R
R
R
R
Y
A
V
A
A
C
A
G
Site 6
S263
V
L
L
A
H
I
V
S
R
L
F
Y
G
K
S
Site 7
Y267
H
I
V
S
R
L
F
Y
G
K
S
Y
Y
H
V
Site 8
Y271
R
L
F
Y
G
K
S
Y
Y
H
V
Y
K
L
T
Site 9
Y272
L
F
Y
G
K
S
Y
Y
H
V
Y
K
L
T
L
Site 10
Y293
N
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Site 11
Y294
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Q
Site 12
S297
P
F
V
Y
Y
F
A
S
R
E
F
Q
L
R
L
Site 13
Y307
F
Q
L
R
L
R
E
Y
L
G
C
R
R
V
P
Site 14
T317
C
R
R
V
P
R
D
T
L
D
T
R
R
E
S
Site 15
T320
V
P
R
D
T
L
D
T
R
R
E
S
L
F
S
Site 16
S324
T
L
D
T
R
R
E
S
L
F
S
A
R
T
T
Site 17
S327
T
R
R
E
S
L
F
S
A
R
T
T
S
V
R
Site 18
T330
E
S
L
F
S
A
R
T
T
S
V
R
S
E
A
Site 19
T331
S
L
F
S
A
R
T
T
S
V
R
S
E
A
G
Site 20
S332
L
F
S
A
R
T
T
S
V
R
S
E
A
G
A
Site 21
S335
A
R
T
T
S
V
R
S
E
A
G
A
H
P
E
Site 22
S357
P
G
L
Q
R
Q
E
S
V
F
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation