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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR5B
Full Name:
WD repeat-containing protein 5B
Alias:
WD repeat domain 5b
Type:
Uncharacterized protein
Mass (Da):
36338
Number AA:
330
UniProt ID:
Q86VZ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
K
A
Q
L
A
L
S
S
S
A
N
Q
S
K
Site 2
S18
A
Q
L
A
L
S
S
S
A
N
Q
S
K
E
V
Site 3
S22
L
S
S
S
A
N
Q
S
K
E
V
P
E
N
P
Site 4
Y31
E
V
P
E
N
P
N
Y
A
L
K
C
T
L
V
Site 5
S45
V
G
H
T
E
A
V
S
S
V
K
F
S
P
N
Site 6
S46
G
H
T
E
A
V
S
S
V
K
F
S
P
N
G
Site 7
S50
A
V
S
S
V
K
F
S
P
N
G
E
W
L
A
Site 8
S58
P
N
G
E
W
L
A
S
S
S
A
D
R
L
I
Site 9
S59
N
G
E
W
L
A
S
S
S
A
D
R
L
I
I
Site 10
S60
G
E
W
L
A
S
S
S
A
D
R
L
I
I
I
Site 11
Y75
W
G
A
Y
D
G
K
Y
E
K
T
L
Y
G
H
Site 12
T78
Y
D
G
K
Y
E
K
T
L
Y
G
H
N
L
E
Site 13
Y80
G
K
Y
E
K
T
L
Y
G
H
N
L
E
I
S
Site 14
S87
Y
G
H
N
L
E
I
S
D
V
A
W
S
S
D
Site 15
S92
E
I
S
D
V
A
W
S
S
D
S
S
R
L
V
Site 16
S93
I
S
D
V
A
W
S
S
D
S
S
R
L
V
S
Site 17
S95
D
V
A
W
S
S
D
S
S
R
L
V
S
A
S
Site 18
S96
V
A
W
S
S
D
S
S
R
L
V
S
A
S
D
Site 19
S100
S
D
S
S
R
L
V
S
A
S
D
D
K
T
L
Site 20
S102
S
S
R
L
V
S
A
S
D
D
K
T
L
K
L
Site 21
T106
V
S
A
S
D
D
K
T
L
K
L
W
D
V
R
Site 22
S114
L
K
L
W
D
V
R
S
G
K
C
L
K
T
L
Site 23
T120
R
S
G
K
C
L
K
T
L
K
G
H
S
N
Y
Site 24
Y127
T
L
K
G
H
S
N
Y
V
F
C
C
N
F
N
Site 25
T148
I
S
G
S
F
D
E
T
V
K
I
W
E
V
K
Site 26
T162
K
T
G
K
C
L
K
T
L
S
A
H
S
D
P
Site 27
S164
G
K
C
L
K
T
L
S
A
H
S
D
P
V
S
Site 28
S167
L
K
T
L
S
A
H
S
D
P
V
S
A
V
H
Site 29
S171
S
A
H
S
D
P
V
S
A
V
H
F
N
C
S
Site 30
T204
A
S
G
Q
C
L
K
T
L
V
D
D
D
N
P
Site 31
S214
D
D
D
N
P
P
V
S
F
V
K
F
S
P
N
Site 32
T233
L
T
A
T
L
D
N
T
L
K
L
W
D
Y
S
Site 33
Y239
N
T
L
K
L
W
D
Y
S
R
G
R
C
L
K
Site 34
T247
S
R
G
R
C
L
K
T
Y
T
G
H
K
N
E
Site 35
Y248
R
G
R
C
L
K
T
Y
T
G
H
K
N
E
K
Site 36
Y256
T
G
H
K
N
E
K
Y
C
I
F
A
N
F
S
Site 37
Y280
G
S
E
D
N
L
V
Y
I
W
N
L
Q
T
K
Site 38
T286
V
Y
I
W
N
L
Q
T
K
E
I
V
Q
K
L
Site 39
T322
A
A
L
E
N
D
K
T
I
K
L
W
M
S
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation