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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM23
Full Name:
Phosphatidylcholine:ceramide cholinephosphotransferase 1
Alias:
EC 2.7.8.27; Mob; SMS1; Sphingomyelin synthase 1; Transmembrane protein 23
Type:
Transferase
Mass (Da):
49208
Number AA:
419
UniProt ID:
Q86VZ5
International Prot ID:
IPI00014863
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000138
GO:0005783
GO:0030173
Uniprot
OncoNet
Molecular Function:
GO:0047493
GO:0016301
GO:0033188
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0016049
GO:0006686
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
S
T
M
K
E
V
V
Y
W
S
P
K
K
V
A
Site 2
S14
M
K
E
V
V
Y
W
S
P
K
K
V
A
D
W
Site 3
Y30
L
E
N
A
M
P
E
Y
C
E
P
L
E
H
F
Site 4
T46
G
Q
D
L
I
N
L
T
Q
E
D
F
K
K
P
Site 5
S59
K
P
P
L
C
R
V
S
S
D
N
G
Q
R
L
Site 6
S60
P
P
L
C
R
V
S
S
D
N
G
Q
R
L
L
Site 7
T72
R
L
L
D
M
I
E
T
L
K
M
E
H
H
L
Site 8
S103
D
I
P
T
P
D
G
S
F
S
I
K
I
K
P
Site 9
S105
P
T
P
D
G
S
F
S
I
K
I
K
P
N
G
Site 10
S132
P
M
P
E
L
E
R
S
Q
Y
P
M
E
W
G
Site 11
Y134
P
E
L
E
R
S
Q
Y
P
M
E
W
G
K
T
Site 12
T178
V
Q
P
P
L
P
D
T
F
F
D
H
F
N
R
Site 13
Y213
I
Q
W
L
L
L
K
Y
K
S
I
I
S
R
R
Site 14
S215
W
L
L
L
K
Y
K
S
I
I
S
R
R
F
F
Site 15
S218
L
K
Y
K
S
I
I
S
R
R
F
F
C
I
V
Site 16
Y286
S
H
N
M
C
G
D
Y
L
Y
S
G
H
T
V
Site 17
Y305
T
Y
L
F
I
K
E
Y
S
P
R
R
L
W
W
Site 18
S366
Q
Q
V
L
K
E
A
S
Q
M
N
L
L
A
R
Site 19
S407
P
W
P
V
V
H
L
S
R
Q
V
K
Y
S
R
Site 20
Y412
H
L
S
R
Q
V
K
Y
S
R
L
V
N
D
T
Site 21
S413
L
S
R
Q
V
K
Y
S
R
L
V
N
D
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation