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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP4Z1
Full Name:
Cytochrome P450 4Z1
Alias:
CYPIVZ1
Type:
Mass (Da):
59086
Number AA:
505
UniProt ID:
Q86W10
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
L
F
Q
V
I
R
L
Y
Q
R
R
R
W
M
I
Site 2
Y55
A
P
P
A
H
W
F
Y
G
H
K
E
F
Y
P
Site 3
Y61
F
Y
G
H
K
E
F
Y
P
V
K
E
F
E
V
Site 4
Y69
P
V
K
E
F
E
V
Y
H
K
L
M
E
K
Y
Site 5
Y76
Y
H
K
L
M
E
K
Y
P
C
A
V
P
L
W
Site 6
Y98
F
S
V
H
D
P
D
Y
A
K
I
L
L
K
R
Site 7
S110
L
K
R
Q
D
P
K
S
A
V
S
H
K
I
L
Site 8
S113
Q
D
P
K
S
A
V
S
H
K
I
L
E
S
W
Site 9
T127
W
V
G
R
G
L
V
T
L
D
G
S
K
W
K
Site 10
S201
C
A
F
S
H
Q
G
S
I
Q
L
D
S
T
L
Site 11
S206
Q
G
S
I
Q
L
D
S
T
L
D
S
Y
L
K
Site 12
T207
G
S
I
Q
L
D
S
T
L
D
S
Y
L
K
A
Site 13
S210
Q
L
D
S
T
L
D
S
Y
L
K
A
V
F
N
Site 14
S219
L
K
A
V
F
N
L
S
K
I
S
N
Q
R
M
Site 15
S240
N
D
L
V
F
K
F
S
S
Q
G
Q
I
F
S
Site 16
S241
D
L
V
F
K
F
S
S
Q
G
Q
I
F
S
K
Site 17
S247
S
S
Q
G
Q
I
F
S
K
F
N
Q
E
L
H
Site 18
S267
V
I
Q
D
R
K
E
S
L
K
D
K
L
K
Q
Site 19
T277
D
K
L
K
Q
D
T
T
Q
K
R
R
W
D
F
Site 20
S290
D
F
L
D
I
L
L
S
A
K
S
E
N
T
K
Site 21
S293
D
I
L
L
S
A
K
S
E
N
T
K
D
F
S
Site 22
T310
D
L
Q
A
E
V
K
T
F
M
F
A
G
H
D
Site 23
Y333
I
L
Y
C
L
A
K
Y
P
E
H
Q
Q
R
C
Site 24
S352
R
E
L
L
G
D
G
S
S
I
T
W
E
H
L
Site 25
S353
E
L
L
G
D
G
S
S
I
T
W
E
H
L
S
Site 26
T355
L
G
D
G
S
S
I
T
W
E
H
L
S
Q
M
Site 27
Y364
E
H
L
S
Q
M
P
Y
T
T
M
C
I
K
E
Site 28
T391
R
L
L
D
K
P
I
T
F
P
D
G
R
S
L
Site 29
S430
V
F
N
P
L
R
F
S
R
E
N
S
E
K
I
Site 30
S434
L
R
F
S
R
E
N
S
E
K
I
H
P
Y
A
Site 31
S480
F
K
L
A
P
D
H
S
R
P
P
Q
P
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation