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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR175
Full Name:
Transmembrane protein adipocyte-associated 1
Alias:
FLJ32197; G protein-coupled receptor 175; GP175; Integral membrane protein GPR175; Seven transmembrane domain orphan receptor; TMEM227; TPRA40; Transmembrane domain protein regulated in adipocytes 40 kDa; Transmembrane protein 227; Transmembrane protein, adipocyte asscociated 1
Type:
Receptor, GPCR
Mass (Da):
41053
Number AA:
373
UniProt ID:
Q86W33
International Prot ID:
IPI00293000
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007568
GO:0006629
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
D
T
L
E
E
V
T
W
A
Site 2
T14
V
T
W
A
N
G
S
T
A
L
P
P
P
L
A
Site 3
Y35
H
R
C
L
L
L
L
Y
E
D
I
G
T
S
R
Site 4
T40
L
L
Y
E
D
I
G
T
S
R
V
R
Y
W
D
Site 5
S144
L
A
F
G
H
L
E
S
K
S
S
I
K
R
V
Site 6
S146
F
G
H
L
E
S
K
S
S
I
K
R
V
L
A
Site 7
S147
G
H
L
E
S
K
S
S
I
K
R
V
L
A
I
Site 8
Y173
Q
G
T
L
E
I
L
Y
P
D
A
H
L
S
A
Site 9
S179
L
Y
P
D
A
H
L
S
A
E
D
F
N
I
Y
Site 10
Y186
S
A
E
D
F
N
I
Y
G
H
G
G
R
Q
F
Site 11
S221
T
P
L
K
E
R
I
S
L
P
S
R
R
S
F
Site 12
S224
K
E
R
I
S
L
P
S
R
R
S
F
Y
V
Y
Site 13
Y294
E
P
K
I
L
F
S
Y
K
C
Q
V
D
E
T
Site 14
T301
Y
K
C
Q
V
D
E
T
E
E
P
D
V
H
L
Site 15
Y312
D
V
H
L
P
Q
P
Y
A
V
A
R
R
E
G
Site 16
S332
A
A
G
A
S
A
A
S
Y
S
S
T
Q
F
D
Site 17
Y333
A
G
A
S
A
A
S
Y
S
S
T
Q
F
D
S
Site 18
S335
A
S
A
A
S
Y
S
S
T
Q
F
D
S
A
G
Site 19
T336
S
A
A
S
Y
S
S
T
Q
F
D
S
A
G
G
Site 20
S352
A
Y
L
D
D
I
A
S
M
P
C
H
T
G
S
Site 21
S359
S
M
P
C
H
T
G
S
I
N
S
T
D
S
E
Site 22
T363
H
T
G
S
I
N
S
T
D
S
E
R
W
K
A
Site 23
S365
G
S
I
N
S
T
D
S
E
R
W
K
A
I
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation