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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMZ2
Full Name:
Archaemetzincin-2
Alias:
Archeobacterial metalloproteinase-like protein 2
Type:
Mass (Da):
41264
Number AA:
360
UniProt ID:
Q86W34
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
I
I
R
H
S
E
Q
T
L
K
T
A
L
I
S
Site 2
T13
H
S
E
Q
T
L
K
T
A
L
I
S
K
N
P
Site 3
S24
S
K
N
P
V
L
V
S
Q
Y
E
K
L
D
A
Site 4
S45
N
E
A
F
Q
P
A
S
D
L
F
G
P
I
T
Site 5
T52
S
D
L
F
G
P
I
T
L
H
S
P
S
D
W
Site 6
S55
F
G
P
I
T
L
H
S
P
S
D
W
I
T
S
Site 7
S57
P
I
T
L
H
S
P
S
D
W
I
T
S
H
P
Site 8
T61
H
S
P
S
D
W
I
T
S
H
P
E
A
P
Q
Site 9
S62
S
P
S
D
W
I
T
S
H
P
E
A
P
Q
D
Site 10
S75
Q
D
F
E
Q
F
F
S
D
P
Y
R
K
T
P
Site 11
Y78
E
Q
F
F
S
D
P
Y
R
K
T
P
S
P
N
Site 12
T81
F
S
D
P
Y
R
K
T
P
S
P
N
K
R
S
Site 13
S83
D
P
Y
R
K
T
P
S
P
N
K
R
S
I
Y
Site 14
S88
T
P
S
P
N
K
R
S
I
Y
I
Q
S
I
G
Site 15
Y90
S
P
N
K
R
S
I
Y
I
Q
S
I
G
S
L
Site 16
S93
K
R
S
I
Y
I
Q
S
I
G
S
L
G
N
T
Site 17
T100
S
I
G
S
L
G
N
T
R
I
I
S
E
E
Y
Site 18
S104
L
G
N
T
R
I
I
S
E
E
Y
I
K
W
L
Site 19
S138
P
V
S
V
T
R
C
S
F
R
V
N
E
N
T
Site 20
T145
S
F
R
V
N
E
N
T
H
N
L
Q
I
H
A
Site 21
Y179
G
I
T
M
I
D
L
Y
P
R
D
S
W
N
F
Site 22
S201
T
D
G
V
G
I
F
S
F
A
R
Y
G
S
D
Site 23
Y205
G
I
F
S
F
A
R
Y
G
S
D
F
Y
S
M
Site 24
Y210
A
R
Y
G
S
D
F
Y
S
M
H
Y
K
G
K
Site 25
S225
V
K
K
L
K
K
T
S
S
S
D
Y
S
I
F
Site 26
S226
K
K
L
K
K
T
S
S
S
D
Y
S
I
F
D
Site 27
Y229
K
K
T
S
S
S
D
Y
S
I
F
D
N
Y
Y
Site 28
S230
K
T
S
S
S
D
Y
S
I
F
D
N
Y
Y
I
Site 29
Y235
D
Y
S
I
F
D
N
Y
Y
I
P
E
I
T
S
Site 30
T251
L
L
L
R
S
C
K
T
L
T
H
E
I
G
H
Site 31
T253
L
R
S
C
K
T
L
T
H
E
I
G
H
I
F
Site 32
S319
V
R
W
I
D
D
E
S
S
D
T
P
G
A
T
Site 33
S320
R
W
I
D
D
E
S
S
D
T
P
G
A
T
P
Site 34
T322
I
D
D
E
S
S
D
T
P
G
A
T
P
E
H
Site 35
T326
S
S
D
T
P
G
A
T
P
E
H
S
H
E
D
Site 36
S330
P
G
A
T
P
E
H
S
H
E
D
N
G
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation