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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
METT10D
Full Name:
Putative methyltransferase METT10D
Alias:
EC 2.1.1.-; LOC79066; MET10; Methyltransferase 10 domain containing; MGC3329; Putative methyltransferase METT10D
Type:
EC 2.1.1.-; Methyltransferase
Mass (Da):
63621
Number AA:
562
UniProt ID:
Q86W50
International Prot ID:
IPI00163391
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008168
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
S
M
H
A
R
N
R
Y
K
D
K
P
P
D
F
Site 2
Y22
D
K
P
P
D
F
A
Y
L
A
S
K
Y
P
D
Site 3
Y27
F
A
Y
L
A
S
K
Y
P
D
F
K
Q
H
V
Site 4
S43
I
N
L
N
G
R
V
S
L
N
F
K
D
P
E
Site 5
T56
P
E
A
V
R
A
L
T
C
T
L
L
R
E
D
Site 6
S67
L
R
E
D
F
G
L
S
I
D
I
P
L
E
R
Site 7
S98
D
L
I
G
H
Q
D
S
D
K
S
T
L
R
R
Site 8
S101
G
H
Q
D
S
D
K
S
T
L
R
R
G
I
D
Site 9
T102
H
Q
D
S
D
K
S
T
L
R
R
G
I
D
I
Site 10
T111
R
R
G
I
D
I
G
T
G
A
S
C
I
Y
P
Site 11
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Site 12
Y178
K
E
E
S
E
I
I
Y
D
F
C
M
C
N
P
Site 13
S208
N
P
R
R
P
P
P
S
S
V
N
T
G
G
I
Site 14
S209
P
R
R
P
P
P
S
S
V
N
T
G
G
I
T
Site 15
T212
P
P
P
S
S
V
N
T
G
G
I
T
E
I
M
Site 16
S235
V
K
R
I
I
H
D
S
L
Q
L
K
K
R
L
Site 17
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Site 18
S254
C
M
L
G
K
K
C
S
L
A
P
L
K
E
E
Site 19
Y272
Q
G
V
P
K
V
T
Y
T
E
F
C
Q
G
R
Site 20
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Site 21
S297
Y
D
D
V
T
V
P
S
P
P
S
K
R
R
K
Site 22
S300
V
T
V
P
S
P
P
S
K
R
R
K
L
E
K
Site 23
S325
A
S
V
M
K
E
L
S
L
K
A
S
P
L
R
Site 24
S329
K
E
L
S
L
K
A
S
P
L
R
S
E
T
A
Site 25
S333
L
K
A
S
P
L
R
S
E
T
A
E
G
I
V
Site 26
T351
T
W
I
E
K
I
L
T
D
L
K
V
Q
H
K
Site 27
T412
A
L
E
E
K
K
P
T
P
K
E
S
G
N
S
Site 28
S416
K
K
P
T
P
K
E
S
G
N
S
Q
E
L
A
Site 29
S419
T
P
K
E
S
G
N
S
Q
E
L
A
R
G
P
Site 30
T430
A
R
G
P
Q
E
R
T
P
C
G
P
A
L
R
Site 31
S450
A
V
E
G
P
C
P
S
Q
E
S
L
S
Q
E
Site 32
S453
G
P
C
P
S
Q
E
S
L
S
Q
E
E
N
P
Site 33
S455
C
P
S
Q
E
S
L
S
Q
E
E
N
P
E
P
Site 34
T463
Q
E
E
N
P
E
P
T
E
D
E
R
S
E
E
Site 35
S468
E
P
T
E
D
E
R
S
E
E
K
G
G
V
E
Site 36
S493
G
A
Q
D
Q
E
A
S
E
Q
F
G
S
P
V
Site 37
S498
E
A
S
E
Q
F
G
S
P
V
A
E
R
G
K
Site 38
Y514
L
P
G
V
A
G
Q
Y
L
F
K
C
L
I
N
Site 39
Y550
L
M
N
Q
L
C
T
Y
I
R
N
Q
I
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation