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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LONP2
Full Name:
Lon protease homolog 2, peroxisomal
Alias:
Lon protease-like protein 2;Peroxisomal Lon protease
Type:
Mass (Da):
94617
Number AA:
852
UniProt ID:
Q86WA8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
S
V
S
P
I
Q
I
P
S
R
Site 2
S27
E
G
V
L
L
P
G
S
T
M
R
T
S
V
D
Site 3
T31
L
P
G
S
T
M
R
T
S
V
D
S
A
R
N
Site 4
S32
P
G
S
T
M
R
T
S
V
D
S
A
R
N
L
Site 5
S35
T
M
R
T
S
V
D
S
A
R
N
L
Q
L
V
Site 6
S44
R
N
L
Q
L
V
R
S
R
L
L
K
G
T
S
Site 7
T50
R
S
R
L
L
K
G
T
S
L
Q
S
T
I
L
Site 8
S68
P
N
T
P
D
P
A
S
D
A
Q
D
L
P
P
Site 9
Y98
S
N
W
P
K
P
H
Y
T
L
L
I
T
G
L
Site 10
Y119
Q
V
L
K
E
K
P
Y
P
I
A
E
V
E
Q
Site 11
T136
R
L
E
E
F
P
N
T
C
K
M
R
E
E
L
Site 12
Y151
G
E
L
S
E
Q
F
Y
K
Y
A
V
Q
L
V
Site 13
Y153
L
S
E
Q
F
Y
K
Y
A
V
Q
L
V
E
M
Site 14
S177
K
L
R
R
L
L
D
S
L
P
R
E
A
L
P
Site 15
S194
L
T
S
I
I
R
T
S
N
K
E
K
L
Q
I
Site 16
T252
I
R
P
I
R
R
I
T
H
I
S
G
T
L
E
Site 17
S255
I
R
R
I
T
H
I
S
G
T
L
E
D
E
D
Site 18
T257
R
I
T
H
I
S
G
T
L
E
D
E
D
E
D
Site 19
S280
L
E
K
K
I
R
T
S
S
M
P
E
Q
A
H
Site 20
S281
E
K
K
I
R
T
S
S
M
P
E
Q
A
H
K
Site 21
S303
R
L
K
K
M
P
Q
S
M
P
E
Y
A
L
T
Site 22
Y307
M
P
Q
S
M
P
E
Y
A
L
T
R
N
Y
L
Site 23
T310
S
M
P
E
Y
A
L
T
R
N
Y
L
E
L
M
Site 24
S325
V
E
L
P
W
N
K
S
T
T
D
R
L
D
I
Site 25
Y344
I
L
L
D
N
D
H
Y
A
M
E
K
L
K
K
Site 26
Y356
L
K
K
R
V
L
E
Y
L
A
V
R
Q
L
K
Site 27
T382
G
P
P
G
V
G
K
T
S
V
G
R
S
V
A
Site 28
S383
P
P
G
V
G
K
T
S
V
G
R
S
V
A
K
Site 29
S387
G
K
T
S
V
G
R
S
V
A
K
T
L
G
R
Site 30
T391
V
G
R
S
V
A
K
T
L
G
R
E
F
H
R
Site 31
S408
L
G
G
V
C
D
Q
S
D
I
R
G
H
R
R
Site 32
T416
D
I
R
G
H
R
R
T
Y
V
G
S
M
P
G
Site 33
Y417
I
R
G
H
R
R
T
Y
V
G
S
M
P
G
R
Site 34
S420
H
R
R
T
Y
V
G
S
M
P
G
R
I
I
N
Site 35
S450
E
V
D
K
L
G
K
S
L
Q
G
D
P
A
A
Site 36
Y475
N
H
N
F
T
D
H
Y
L
N
V
A
F
D
L
Site 37
Y513
E
I
I
Q
V
P
G
Y
T
Q
E
E
K
I
E
Site 38
T537
Q
L
E
Q
H
G
L
T
P
Q
Q
I
Q
I
P
Site 39
Y555
T
L
D
I
I
T
R
Y
T
R
E
A
G
V
R
Site 40
T556
L
D
I
I
T
R
Y
T
R
E
A
G
V
R
S
Site 41
S563
T
R
E
A
G
V
R
S
L
D
R
K
L
G
A
Site 42
S592
K
E
A
K
L
D
R
S
D
V
T
E
R
E
G
Site 43
T595
K
L
D
R
S
D
V
T
E
R
E
G
C
R
E
Site 44
S612
L
E
D
E
K
P
E
S
I
S
D
T
T
D
L
Site 45
S614
D
E
K
P
E
S
I
S
D
T
T
D
L
A
L
Site 46
T616
K
P
E
S
I
S
D
T
T
D
L
A
L
P
P
Site 47
T617
P
E
S
I
S
D
T
T
D
L
A
L
P
P
E
Site 48
Y643
D
I
L
G
P
P
M
Y
E
M
E
V
S
Q
R
Site 49
S648
P
M
Y
E
M
E
V
S
Q
R
L
S
Q
P
G
Site 50
S652
M
E
V
S
Q
R
L
S
Q
P
G
V
A
I
G
Site 51
T684
M
D
G
E
G
Q
L
T
L
T
G
Q
L
G
D
Site 52
S702
E
S
A
H
L
A
I
S
W
L
R
S
N
A
K
Site 53
S706
L
A
I
S
W
L
R
S
N
A
K
K
Y
Q
L
Site 54
T714
N
A
K
K
Y
Q
L
T
N
A
F
G
S
F
D
Site 55
S719
Q
L
T
N
A
F
G
S
F
D
L
L
D
N
T
Site 56
T726
S
F
D
L
L
D
N
T
D
I
H
L
H
F
P
Site 57
T843
D
G
G
F
T
V
K
T
R
P
G
L
L
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation