PhosphoNET

           
Protein Info 
   
Short Name:  ZC3HC1
Full Name:  Nuclear-interacting partner of ALK
Alias:  NIPA; Nuclear interacting partner of ALK; Nuclear interaction partner of ALK; Nuclear-interacting partner of anaplastic lymphoma kinase; Zinc finger, C3HC-type containing 1
Type:  Ubiquitin conjugating system; Cell cycle regulation
Mass (Da):  55262
Number AA:  502
UniProt ID:  Q86WB0
International Prot ID:  IPI00301421
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0019901  GO:0008270  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0051301  GO:0007067  GO:0019941 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S24NWGAVVRSPEGTPQK
Site 2T28VVRSPEGTPQKIRQL
Site 3T52GGVDAKDTSATSQSV
Site 4S53GVDAKDTSATSQSVN
Site 5S56AKDTSATSQSVNGSP
Site 6S58DTSATSQSVNGSPQA
Site 7S62TSQSVNGSPQAEQPS
Site 8S69SPQAEQPSLESTSKE
Site 9T73EQPSLESTSKEAFFS
Site 10S80TSKEAFFSRVETFSS
Site 11S86FSRVETFSSLKWAGK
Site 12S87SRVETFSSLKWAGKP
Site 13S98AGKPFELSPLVCAKY
Site 14Y105SPLVCAKYGWVTVEC
Site 15Y137PAFDFDRYKQRCAEL
Site 16S161KFCFWPDSPSPDRFG
Site 17S163CFWPDSPSPDRFGML
Site 18S188EFLDRFQSLCHLDLQ
Site 19S198HLDLQLPSLRPEDLK
Site 20T206LRPEDLKTMCLTEDK
Site 21T229EDELDHRTDERKTTI
Site 22T234HRTDERKTTIKLGSD
Site 23T235RTDERKTTIKLGSDI
Site 24S259SVCGWACSSSLESMQ
Site 25S261CGWACSSSLESMQLS
Site 26S290GFQQIESSMTDLDAS
Site 27T292QQIESSMTDLDASFG
Site 28S297SMTDLDASFGLTSSP
Site 29S321RLPLVPESPRRMMTR
Site 30T327ESPRRMMTRSQDATF
Site 31S329PRRMMTRSQDATFSP
Site 32T333MTRSQDATFSPGSEQ
Site 33S335RSQDATFSPGSEQAE
Site 34S338DATFSPGSEQAEKSP
Site 35S344GSEQAEKSPGPIVSR
Site 36S350KSPGPIVSRTRSWDS
Site 37T352PGPIVSRTRSWDSSS
Site 38S354 PIVSRTRSWDSSSPV
Site 39S357SRTRSWDSSSPVDRP
Site 40S358RTRSWDSSSPVDRPE
Site 41S359TRSWDSSSPVDRPEP
Site 42S370RPEPEAASPTTRTRP
Site 43T372EPEAASPTTRTRPVT
Site 44T379TTRTRPVTRSMGTGD
Site 45S381RTRPVTRSMGTGDTP
Site 46T384PVTRSMGTGDTPGLE
Site 47T387RSMGTGDTPGLEVPS
Site 48S394TPGLEVPSSPLRKAK
Site 49S395PGLEVPSSPLRKAKR
Site 50S407AKRARLCSSSSSDTS
Site 51S408KRARLCSSSSSDTSS
Site 52S409RARLCSSSSSDTSSR
Site 53S410ARLCSSSSSDTSSRS
Site 54S411RLCSSSSSDTSSRSF
Site 55T413CSSSSSDTSSRSFFD
Site 56S414SSSSSDTSSRSFFDP
Site 57S415SSSSDTSSRSFFDPT
Site 58S417SSDTSSRSFFDPTSQ
Site 59T422SRSFFDPTSQHRDWC
Site 60T446ESRENGGTEPDASAP
Site 61S451GGTEPDASAPAEPGW
Site 62S471ILLAHKQSSQPAETD
Site 63S472LLAHKQSSQPAETDS
Site 64T477QSSQPAETDSMSLSE
Site 65S479SQPAETDSMSLSEKS
Site 66S481PAETDSMSLSEKSRK
Site 67S483ETDSMSLSEKSRKVF
Site 68S486SMSLSEKSRKVFRIF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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