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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM69
Full Name:
Tripartite motif-containing protein 69
Alias:
RFP-like domain-containing protein trimless;RING finger protein 36
Type:
Mass (Da):
57419
Number AA:
500
UniProt ID:
Q86WT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
V
S
T
N
P
S
S
N
I
D
P
G
D
Site 2
S9
E
V
S
T
N
P
S
S
N
I
D
P
G
D
Y
Site 3
Y16
S
N
I
D
P
G
D
Y
V
E
M
N
D
S
I
Site 4
S22
D
Y
V
E
M
N
D
S
I
T
H
L
P
S
K
Site 5
T24
V
E
M
N
D
S
I
T
H
L
P
S
K
V
V
Site 6
S143
Q
C
K
D
A
R
L
S
V
G
Q
S
K
E
F
Site 7
S147
A
R
L
S
V
G
Q
S
K
E
F
L
Q
I
S
Site 8
T180
T
T
L
K
E
L
Q
T
L
R
N
M
Q
K
E
Site 9
T223
S
K
E
K
D
I
L
T
E
L
R
E
E
G
K
Site 10
S241
E
E
M
E
L
N
L
S
Q
L
Q
E
Q
C
L
Site 11
T261
L
V
S
I
Q
A
K
T
E
Q
Q
N
S
F
D
Site 12
S266
A
K
T
E
Q
Q
N
S
F
D
F
L
K
D
I
Site 13
T275
D
F
L
K
D
I
T
T
L
L
H
S
L
E
Q
Site 14
T289
Q
G
M
K
V
L
A
T
R
E
L
I
S
R
K
Site 15
S294
L
A
T
R
E
L
I
S
R
K
L
N
L
G
Q
Site 16
Y302
R
K
L
N
L
G
Q
Y
K
G
P
I
Q
Y
M
Site 17
T317
V
W
R
E
M
Q
D
T
L
C
P
G
L
S
P
Site 18
S323
D
T
L
C
P
G
L
S
P
L
T
L
D
P
K
Site 19
T326
C
P
G
L
S
P
L
T
L
D
P
K
T
A
H
Site 20
S339
A
H
P
N
L
V
L
S
K
S
Q
T
S
V
W
Site 21
S341
P
N
L
V
L
S
K
S
Q
T
S
V
W
H
G
Site 22
T343
L
V
L
S
K
S
Q
T
S
V
W
H
G
D
I
Site 23
S363
D
D
P
E
R
F
D
S
S
V
A
V
L
G
S
Site 24
S364
D
P
E
R
F
D
S
S
V
A
V
L
G
S
R
Site 25
S370
S
S
V
A
V
L
G
S
R
G
F
T
S
G
K
Site 26
T374
V
L
G
S
R
G
F
T
S
G
K
W
Y
W
E
Site 27
Y379
G
F
T
S
G
K
W
Y
W
E
V
E
V
A
K
Site 28
S404
E
S
I
I
R
K
G
S
C
P
L
T
P
E
Q
Site 29
T408
R
K
G
S
C
P
L
T
P
E
Q
G
F
W
L
Site 30
T422
L
L
R
L
R
N
Q
T
D
L
K
A
L
D
L
Site 31
T435
D
L
P
S
F
S
L
T
L
T
N
N
L
D
K
Site 32
T437
P
S
F
S
L
T
L
T
N
N
L
D
K
V
G
Site 33
Y446
N
L
D
K
V
G
I
Y
L
D
Y
E
G
G
Q
Site 34
Y449
K
V
G
I
Y
L
D
Y
E
G
G
Q
L
S
F
Site 35
S455
D
Y
E
G
G
Q
L
S
F
Y
N
A
K
T
M
Site 36
Y457
E
G
G
Q
L
S
F
Y
N
A
K
T
M
T
H
Site 37
Y466
A
K
T
M
T
H
I
Y
T
F
S
N
T
F
M
Site 38
Y479
F
M
E
K
L
Y
P
Y
F
C
P
C
L
N
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation