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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC6
Full Name:
Leucine-rich repeat-containing protein 6
Alias:
Leucine-rich testis-specific protein;Testis-specific leucine-rich repeat protein
Type:
Mass (Da):
54255
Number AA:
466
UniProt ID:
Q86X45
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y70
S
K
L
K
K
L
E
Y
L
N
L
A
L
N
N
Site 2
S105
N
F
I
G
E
L
S
S
I
K
N
L
Q
H
N
Site 3
Y131
P
C
A
S
F
D
H
Y
R
E
F
V
V
A
T
Site 4
S153
D
G
K
E
I
E
P
S
E
R
I
K
A
L
Q
Site 5
Y162
R
I
K
A
L
Q
D
Y
S
V
I
E
P
Q
I
Site 6
S163
I
K
A
L
Q
D
Y
S
V
I
E
P
Q
I
R
Site 7
S202
D
K
N
E
D
K
R
S
N
A
G
F
D
G
R
Site 8
Y211
A
G
F
D
G
R
W
Y
T
D
I
N
A
T
L
Site 9
T212
G
F
D
G
R
W
Y
T
D
I
N
A
T
L
S
Site 10
S219
T
D
I
N
A
T
L
S
S
L
E
S
K
D
H
Site 11
S220
D
I
N
A
T
L
S
S
L
E
S
K
D
H
L
Site 12
S223
A
T
L
S
S
L
E
S
K
D
H
L
Q
A
P
Site 13
T232
D
H
L
Q
A
P
D
T
E
E
H
N
T
K
K
Site 14
T237
P
D
T
E
E
H
N
T
K
K
L
D
N
S
E
Site 15
S243
N
T
K
K
L
D
N
S
E
D
D
L
E
F
W
Site 16
T257
W
N
K
P
C
L
F
T
P
E
S
R
L
E
T
Site 17
S260
P
C
L
F
T
P
E
S
R
L
E
T
L
R
H
Site 18
T264
T
P
E
S
R
L
E
T
L
R
H
M
E
K
Q
Site 19
S279
R
K
K
Q
E
K
L
S
E
K
K
K
K
V
K
Site 20
T290
K
K
V
K
P
P
R
T
L
I
T
E
D
G
K
Site 21
S309
N
E
P
K
I
D
F
S
L
K
D
N
E
K
Q
Site 22
S330
V
Y
R
Y
M
D
T
S
L
I
D
V
D
V
Q
Site 23
Y340
D
V
D
V
Q
P
T
Y
V
R
V
M
I
K
G
Site 24
S362
P
A
E
V
K
P
D
S
S
S
A
K
R
S
Q
Site 25
S364
E
V
K
P
D
S
S
S
A
K
R
S
Q
T
T
Site 26
S368
D
S
S
S
A
K
R
S
Q
T
T
G
H
L
V
Site 27
T370
S
S
A
K
R
S
Q
T
T
G
H
L
V
I
C
Site 28
S394
G
G
Q
R
A
F
K
S
M
K
T
T
S
D
R
Site 29
T397
R
A
F
K
S
M
K
T
T
S
D
R
S
R
E
Site 30
T398
A
F
K
S
M
K
T
T
S
D
R
S
R
E
Q
Site 31
S399
F
K
S
M
K
T
T
S
D
R
S
R
E
Q
T
Site 32
T406
S
D
R
S
R
E
Q
T
N
T
R
S
K
H
M
Site 33
T408
R
S
R
E
Q
T
N
T
R
S
K
H
M
E
K
Site 34
S421
E
K
L
E
V
D
P
S
K
H
S
F
P
D
V
Site 35
S424
E
V
D
P
S
K
H
S
F
P
D
V
T
N
I
Site 36
T429
K
H
S
F
P
D
V
T
N
I
V
Q
E
K
K
Site 37
T438
I
V
Q
E
K
K
H
T
P
R
R
R
P
E
P
Site 38
S450
P
E
P
K
I
I
P
S
E
E
D
P
T
F
E
Site 39
T455
I
P
S
E
E
D
P
T
F
E
D
N
P
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation