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Updated November 2019
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Protein Info
Short Name:
FAM131B
Full Name:
Protein FAM131B
Alias:
F131B; family with sequence similarity 131, member B; KIAA0773
Type:
Unknown function
Mass (Da):
35769
Number AA:
332
UniProt ID:
Q86XD5
International Prot ID:
IPI00641986
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
D
S
T
S
S
L
H
G
S
S
L
Site 2
S6
_
_
M
D
S
T
S
S
L
H
G
S
S
L
H
Site 3
S10
S
T
S
S
L
H
G
S
S
L
H
R
P
S
T
Site 4
S11
T
S
S
L
H
G
S
S
L
H
R
P
S
T
E
Site 5
S16
G
S
S
L
H
R
P
S
T
E
Q
T
R
T
D
Site 6
T17
S
S
L
H
R
P
S
T
E
Q
T
R
T
D
F
Site 7
T20
H
R
P
S
T
E
Q
T
R
T
D
F
S
W
D
Site 8
T22
P
S
T
E
Q
T
R
T
D
F
S
W
D
G
I
Site 9
S32
S
W
D
G
I
N
L
S
M
E
D
T
T
S
I
Site 10
S38
L
S
M
E
D
T
T
S
I
L
P
K
L
K
R
Site 11
S47
L
P
K
L
K
R
N
S
N
A
Y
G
I
G
A
Site 12
Y50
L
K
R
N
S
N
A
Y
G
I
G
A
L
A
K
Site 13
S61
A
L
A
K
S
S
F
S
G
I
S
R
S
M
K
Site 14
S64
K
S
S
F
S
G
I
S
R
S
M
K
D
H
V
Site 15
S66
S
F
S
G
I
S
R
S
M
K
D
H
V
T
K
Site 16
T72
R
S
M
K
D
H
V
T
K
P
T
A
M
G
Q
Site 17
S105
Q
P
Q
H
S
H
E
S
V
R
R
D
T
D
A
Site 18
T110
H
E
S
V
R
R
D
T
D
A
Y
S
D
L
S
Site 19
Y113
V
R
R
D
T
D
A
Y
S
D
L
S
D
G
E
Site 20
S114
R
R
D
T
D
A
Y
S
D
L
S
D
G
E
K
Site 21
S117
T
D
A
Y
S
D
L
S
D
G
E
K
E
A
R
Site 22
S145
A
T
L
M
A
W
S
S
M
D
G
E
D
M
S
Site 23
S152
S
M
D
G
E
D
M
S
V
N
S
T
Q
E
P
Site 24
S155
G
E
D
M
S
V
N
S
T
Q
E
P
L
G
C
Site 25
T156
E
D
M
S
V
N
S
T
Q
E
P
L
G
C
N
Site 26
Y168
G
C
N
Y
S
D
N
Y
Q
E
L
M
D
S
Q
Site 27
S174
N
Y
Q
E
L
M
D
S
Q
D
A
L
A
Q
A
Site 28
Y196
S
Y
V
S
Q
G
M
Y
C
L
G
S
S
D
A
Site 29
S201
G
M
Y
C
L
G
S
S
D
A
W
E
A
S
D
Site 30
S207
S
S
D
A
W
E
A
S
D
Q
S
L
I
A
S
Site 31
S210
A
W
E
A
S
D
Q
S
L
I
A
S
P
A
T
Site 32
S214
S
D
Q
S
L
I
A
S
P
A
T
G
S
Y
L
Site 33
Y220
A
S
P
A
T
G
S
Y
L
G
P
A
F
D
D
Site 34
S228
L
G
P
A
F
D
D
S
Q
P
S
L
H
E
M
Site 35
S231
A
F
D
D
S
Q
P
S
L
H
E
M
G
P
S
Site 36
S238
S
L
H
E
M
G
P
S
Q
P
A
S
G
Y
S
Site 37
S242
M
G
P
S
Q
P
A
S
G
Y
S
A
L
E
P
Site 38
T257
P
P
L
L
G
G
D
T
D
W
A
P
G
V
G
Site 39
S295
A
G
C
R
D
L
E
S
L
S
P
R
E
D
P
Site 40
S297
C
R
D
L
E
S
L
S
P
R
E
D
P
E
M
Site 41
S305
P
R
E
D
P
E
M
S
T
A
L
S
R
K
V
Site 42
S309
P
E
M
S
T
A
L
S
R
K
V
S
D
V
T
Site 43
S313
T
A
L
S
R
K
V
S
D
V
T
S
S
G
V
Site 44
T316
S
R
K
V
S
D
V
T
S
S
G
V
Q
S
F
Site 45
S317
R
K
V
S
D
V
T
S
S
G
V
Q
S
F
D
Site 46
S318
K
V
S
D
V
T
S
S
G
V
Q
S
F
D
E
Site 47
S322
V
T
S
S
G
V
Q
S
F
D
E
E
E
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation