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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IQCA1
Full Name:
IQ and AAA domain-containing protein 1
Alias:
Type:
Mass (Da):
95341
Number AA:
822
UniProt ID:
Q86XH1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y100
L
E
L
T
E
F
H
Y
F
D
D
I
L
Q
D
Site 2
Y122
L
D
I
P
I
P
K
Y
F
L
K
E
K
L
E
Site 3
T149
L
A
D
S
G
I
D
T
S
D
M
K
Y
P
V
Site 4
S150
A
D
S
G
I
D
T
S
D
M
K
Y
P
V
K
Site 5
Y154
I
D
T
S
D
M
K
Y
P
V
K
S
I
P
F
Site 6
S158
D
M
K
Y
P
V
K
S
I
P
F
D
E
A
V
Site 7
Y188
A
L
F
M
K
Q
I
Y
L
Q
E
Y
R
A
K
Site 8
Y192
K
Q
I
Y
L
Q
E
Y
R
A
K
Q
S
K
M
Site 9
T227
R
F
H
Q
R
K
E
T
E
K
L
R
E
E
E
Site 10
Y274
Q
I
K
H
E
E
D
Y
R
E
A
L
V
T
I
Site 11
T280
D
Y
R
E
A
L
V
T
I
K
N
D
L
K
L
Site 12
T312
F
I
E
C
R
N
L
T
G
T
F
P
D
Y
P
Site 13
T314
E
C
R
N
L
T
G
T
F
P
D
Y
P
D
V
Site 14
Y318
L
T
G
T
F
P
D
Y
P
D
V
E
E
G
G
Site 15
S326
P
D
V
E
E
G
G
S
A
I
I
F
S
D
K
Site 16
T334
A
I
I
F
S
D
K
T
I
Q
Q
V
I
E
D
Site 17
S387
E
D
E
K
W
K
M
S
P
S
L
F
L
P
A
Site 18
S389
E
K
W
K
M
S
P
S
L
F
L
P
A
M
K
Site 19
S416
K
D
E
S
W
N
F
S
Q
D
Y
D
P
E
L
Site 20
Y419
S
W
N
F
S
Q
D
Y
D
P
E
L
I
K
E
Site 21
S434
E
K
R
K
E
L
Q
S
E
I
R
I
Q
V
D
Site 22
T490
A
K
K
D
K
D
L
T
A
D
R
T
I
E
S
Site 23
T494
K
D
L
T
A
D
R
T
I
E
S
L
Y
K
E
Site 24
S497
T
A
D
R
T
I
E
S
L
Y
K
E
L
V
E
Site 25
Y499
D
R
T
I
E
S
L
Y
K
E
L
V
E
E
G
Site 26
S517
Q
A
L
K
V
N
L
S
D
Y
I
G
E
Y
S
Site 27
Y519
L
K
V
N
L
S
D
Y
I
G
E
Y
S
Y
L
Site 28
Y523
L
S
D
Y
I
G
E
Y
S
Y
L
G
T
T
L
Site 29
S524
S
D
Y
I
G
E
Y
S
Y
L
G
T
T
L
R
Site 30
Y525
D
Y
I
G
E
Y
S
Y
L
G
T
T
L
R
Q
Site 31
T528
G
E
Y
S
Y
L
G
T
T
L
R
Q
V
S
I
Site 32
S534
G
T
T
L
R
Q
V
S
I
E
P
M
P
S
L
Site 33
S600
G
A
N
L
F
N
L
S
S
S
N
I
A
G
K
Site 34
S601
A
N
L
F
N
L
S
S
S
N
I
A
G
K
Y
Site 35
S602
N
L
F
N
L
S
S
S
N
I
A
G
K
Y
P
Site 36
Y608
S
S
N
I
A
G
K
Y
P
G
K
N
G
L
Q
Site 37
S631
V
A
R
Q
L
Q
P
S
V
V
W
I
E
D
T
Site 38
T638
S
V
V
W
I
E
D
T
E
K
T
F
Y
K
K
Site 39
T641
W
I
E
D
T
E
K
T
F
Y
K
K
V
P
N
Site 40
Y643
E
D
T
E
K
T
F
Y
K
K
V
P
N
A
E
Site 41
T680
D
R
I
L
I
V
G
T
T
R
R
P
F
D
A
Site 42
T681
R
I
L
I
V
G
T
T
R
R
P
F
D
A
E
Site 43
S709
V
P
R
P
D
Y
A
S
R
Y
V
L
W
K
Q
Site 44
Y711
R
P
D
Y
A
S
R
Y
V
L
W
K
Q
I
I
Site 45
T774
L
T
A
V
E
F
I
T
A
I
T
S
M
N
P
Site 46
Y783
I
T
S
M
N
P
V
Y
K
E
E
E
E
S
F
Site 47
Y794
E
E
S
F
K
N
W
Y
A
K
T
P
L
G
K
Site 48
T797
F
K
N
W
Y
A
K
T
P
L
G
K
K
R
A
Site 49
T808
K
K
R
A
L
A
I
T
G
G
S
T
E
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation