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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R3B
Full Name:
Protein phosphatase 1 regulatory subunit 3B
Alias:
Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL;Protein phosphatase 1 regulatory subunit 4;Protein phosphatase 1 subunit GL
Type:
Mass (Da):
32695
Number AA:
285
UniProt ID:
Q86XI6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
A
V
D
I
E
Y
R
Y
N
C
M
A
P
S
L
Site 2
S16
R
Y
N
C
M
A
P
S
L
R
Q
E
R
F
A
Site 3
S27
E
R
F
A
F
K
I
S
P
K
P
S
K
P
L
Site 4
S31
F
K
I
S
P
K
P
S
K
P
L
R
P
C
I
Site 5
S41
L
R
P
C
I
Q
L
S
S
K
N
E
A
S
G
Site 6
S42
R
P
C
I
Q
L
S
S
K
N
E
A
S
G
M
Site 7
S64
K
K
V
K
K
R
V
S
F
A
D
N
Q
G
L
Site 8
S101
E
L
L
D
N
I
V
S
L
T
T
A
E
S
E
Site 9
S109
L
T
T
A
E
S
E
S
F
V
L
D
F
S
Q
Site 10
S115
E
S
F
V
L
D
F
S
Q
P
S
A
D
Y
L
Site 11
Y121
F
S
Q
P
S
A
D
Y
L
D
F
R
N
R
L
Site 12
T148
K
D
K
A
I
A
G
T
V
K
V
Q
N
L
A
Site 13
T159
Q
N
L
A
F
E
K
T
V
K
I
R
M
T
F
Site 14
T165
K
T
V
K
I
R
M
T
F
D
T
W
K
S
Y
Site 15
Y172
T
F
D
T
W
K
S
Y
T
D
F
P
C
Q
Y
Site 16
Y179
Y
T
D
F
P
C
Q
Y
V
K
D
T
Y
A
G
Site 17
T183
P
C
Q
Y
V
K
D
T
Y
A
G
S
D
R
D
Site 18
Y184
C
Q
Y
V
K
D
T
Y
A
G
S
D
R
D
T
Site 19
S187
V
K
D
T
Y
A
G
S
D
R
D
T
F
S
F
Site 20
T191
Y
A
G
S
D
R
D
T
F
S
F
D
I
S
L
Site 21
S193
G
S
D
R
D
T
F
S
F
D
I
S
L
P
E
Site 22
S197
D
T
F
S
F
D
I
S
L
P
E
K
I
Q
S
Site 23
S204
S
L
P
E
K
I
Q
S
Y
E
R
M
E
F
A
Site 24
Y205
L
P
E
K
I
Q
S
Y
E
R
M
E
F
A
V
Site 25
Y213
E
R
M
E
F
A
V
Y
Y
E
C
N
G
Q
T
Site 26
Y214
R
M
E
F
A
V
Y
Y
E
C
N
G
Q
T
Y
Site 27
Y230
D
S
N
R
G
K
N
Y
R
I
I
R
A
E
L
Site 28
S239
I
I
R
A
E
L
K
S
T
Q
G
M
T
K
P
Site 29
T240
I
R
A
E
L
K
S
T
Q
G
M
T
K
P
H
Site 30
T244
L
K
S
T
Q
G
M
T
K
P
H
S
G
P
D
Site 31
S248
Q
G
M
T
K
P
H
S
G
P
D
L
G
I
S
Site 32
S255
S
G
P
D
L
G
I
S
F
D
Q
F
G
S
P
Site 33
S261
I
S
F
D
Q
F
G
S
P
R
C
S
Y
G
L
Site 34
S265
Q
F
G
S
P
R
C
S
Y
G
L
F
P
E
W
Site 35
Y266
F
G
S
P
R
C
S
Y
G
L
F
P
E
W
P
Site 36
Y275
L
F
P
E
W
P
S
Y
L
G
Y
E
K
L
G
Site 37
Y278
E
W
P
S
Y
L
G
Y
E
K
L
G
P
Y
Y
Site 38
Y285
Y
E
K
L
G
P
Y
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation