PhosphoNET

           
Protein Info 
   
Short Name:  TMEM146
Full Name:  Transmembrane protein 146
Alias:  Loc257062; MGC39581; TM146
Type: 
Mass (Da):  90468
Number AA:  798
UniProt ID:  Q86XM0
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S206GGIFHFFSLSQVAML
Site 2S208IFHFFSLSQVAMLVV
Site 3S225GKGMFKYSDHPLNRS
Site 4S236LNRSFGLSFDYNGTL
Site 5Y317TREDNLYYGNLGIVP
Site 6T743SVWLAYKTPKLLRTA
Site 7T749KTPKLLRTARGRRIK
Site 8T768QLCRRCKTVCQFRAS
Site 9S775TVCQFRASATARAGT
Site 10T782SATARAGTEPPGRHR
Site 11T790EPPGRHRTPHGGRSD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation