KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PLA2G4D
Full Name:
Cytosolic phospholipase A2 delta
Alias:
Phospholipase A2 group IVD
Type:
Mass (Da):
91952
Number AA:
818
UniProt ID:
Q86XP0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
S
L
S
P
G
G
P
T
G
H
Site 2
Y14
G
G
P
T
G
H
P
Y
Q
G
E
A
S
T
C
Site 3
T63
G
M
K
F
K
T
K
T
L
T
D
T
S
H
P
Site 4
T65
K
F
K
T
K
T
L
T
D
T
S
H
P
V
W
Site 5
T67
K
T
K
T
L
T
D
T
S
H
P
V
W
N
E
Site 6
S91
V
K
N
V
L
E
L
S
I
Y
D
E
D
S
V
Site 7
Y93
N
V
L
E
L
S
I
Y
D
E
D
S
V
T
E
Site 8
S97
L
S
I
Y
D
E
D
S
V
T
E
D
D
I
C
Site 9
T99
I
Y
D
E
D
S
V
T
E
D
D
I
C
F
K
Site 10
T123
P
G
K
L
L
R
K
T
F
S
Q
S
P
Q
G
Site 11
S125
K
L
L
R
K
T
F
S
Q
S
P
Q
G
E
E
Site 12
S127
L
R
K
T
F
S
Q
S
P
Q
G
E
E
E
L
Site 13
S144
E
F
L
M
E
E
T
S
D
R
P
E
N
L
I
Site 14
T152
D
R
P
E
N
L
I
T
N
K
V
I
V
A
R
Site 15
T174
H
L
D
S
T
G
S
T
A
V
V
A
D
Q
D
Site 16
S192
L
E
L
V
L
K
G
S
Y
E
D
T
Q
T
S
Site 17
T196
L
K
G
S
Y
E
D
T
Q
T
S
F
L
G
T
Site 18
T198
G
S
Y
E
D
T
Q
T
S
F
L
G
T
A
S
Site 19
S199
S
Y
E
D
T
Q
T
S
F
L
G
T
A
S
A
Site 20
T203
T
Q
T
S
F
L
G
T
A
S
A
F
R
F
H
Site 21
Y211
A
S
A
F
R
F
H
Y
M
A
A
L
E
T
E
Site 22
S220
A
A
L
E
T
E
L
S
G
R
L
R
S
S
R
Site 23
S225
E
L
S
G
R
L
R
S
S
R
S
N
G
W
N
Site 24
S226
L
S
G
R
L
R
S
S
R
S
N
G
W
N
G
Site 25
S228
G
R
L
R
S
S
R
S
N
G
W
N
G
D
N
Site 26
S236
N
G
W
N
G
D
N
S
A
G
Y
L
T
V
P
Site 27
Y239
N
G
D
N
S
A
G
Y
L
T
V
P
L
R
P
Site 28
T241
D
N
S
A
G
Y
L
T
V
P
L
R
P
L
T
Site 29
S295
A
E
E
Q
A
F
L
S
R
R
K
Q
V
V
A
Site 30
S377
L
Y
G
D
P
E
W
S
Q
R
D
L
E
G
P
Site 31
Y387
D
L
E
G
P
I
R
Y
A
R
E
H
L
A
K
Site 32
S401
K
S
K
L
E
V
F
S
P
E
R
L
A
S
Y
Site 33
S407
F
S
P
E
R
L
A
S
Y
R
R
E
L
E
L
Site 34
Y408
S
P
E
R
L
A
S
Y
R
R
E
L
E
L
R
Site 35
T423
A
E
Q
G
H
P
T
T
F
V
D
L
W
A
L
Site 36
Y462
G
Q
N
P
L
P
L
Y
L
S
L
N
V
K
E
Site 37
S464
N
P
L
P
L
Y
L
S
L
N
V
K
E
N
N
Site 38
S484
F
K
E
W
V
E
F
S
P
Y
E
V
G
F
L
Site 39
Y486
E
W
V
E
F
S
P
Y
E
V
G
F
L
K
Y
Site 40
Y540
L
N
L
L
D
A
W
Y
D
L
T
S
S
G
E
Site 41
T543
L
D
A
W
Y
D
L
T
S
S
G
E
S
W
K
Site 42
S544
D
A
W
Y
D
L
T
S
S
G
E
S
W
K
Q
Site 43
S548
D
L
T
S
S
G
E
S
W
K
Q
H
I
K
D
Site 44
T557
K
Q
H
I
K
D
K
T
R
S
L
E
K
E
P
Site 45
S559
H
I
K
D
K
T
R
S
L
E
K
E
P
L
T
Site 46
T566
S
L
E
K
E
P
L
T
T
S
G
T
S
S
R
Site 47
T567
L
E
K
E
P
L
T
T
S
G
T
S
S
R
L
Site 48
S568
E
K
E
P
L
T
T
S
G
T
S
S
R
L
E
Site 49
T570
E
P
L
T
T
S
G
T
S
S
R
L
E
A
S
Site 50
S572
L
T
T
S
G
T
S
S
R
L
E
A
S
W
L
Site 51
T594
Q
A
F
K
G
F
L
T
G
R
P
L
H
Q
R
Site 52
S602
G
R
P
L
H
Q
R
S
P
N
F
L
Q
G
L
Site 53
Y615
G
L
Q
L
H
Q
D
Y
C
S
H
K
D
F
S
Site 54
Y627
D
F
S
T
W
A
D
Y
Q
L
D
S
M
P
S
Site 55
S631
W
A
D
Y
Q
L
D
S
M
P
S
Q
L
T
P
Site 56
T637
D
S
M
P
S
Q
L
T
P
K
E
P
R
L
C
Site 57
T654
D
A
A
Y
F
I
N
T
S
S
P
S
M
F
R
Site 58
S656
A
Y
F
I
N
T
S
S
P
S
M
F
R
P
G
Site 59
S658
F
I
N
T
S
S
P
S
M
F
R
P
G
R
R
Site 60
Y689
A
L
Q
Q
T
E
L
Y
C
R
A
R
G
L
P
Site 61
S703
P
F
P
R
V
E
P
S
P
Q
D
Q
H
Q
P
Site 62
S717
P
R
E
C
H
L
F
S
D
P
A
C
P
E
A
Site 63
S736
H
F
P
L
V
N
A
S
F
K
D
H
S
A
P
Site 64
S748
S
A
P
G
V
Q
R
S
P
A
E
L
Q
G
G
Site 65
T760
Q
G
G
Q
V
D
L
T
G
A
T
C
P
Y
T
Site 66
T767
T
G
A
T
C
P
Y
T
L
S
N
M
T
Y
K
Site 67
Y773
Y
T
L
S
N
M
T
Y
K
E
E
D
F
E
R
Site 68
S785
F
E
R
L
L
R
L
S
D
Y
N
V
Q
T
S
Site 69
Y787
R
L
L
R
L
S
D
Y
N
V
Q
T
S
Q
G
Site 70
S792
S
D
Y
N
V
Q
T
S
Q
G
A
I
L
Q
A
Site 71
T808
R
T
A
L
K
H
R
T
L
E
A
R
P
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation