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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF677
Full Name:
Zinc finger protein 677
Alias:
Type:
Mass (Da):
67996
Number AA:
584
UniProt ID:
Q86XU0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
K
D
V
A
I
E
F
S
Q
E
E
W
E
C
L
Site 2
Y33
D
P
A
Q
R
A
L
Y
R
D
V
M
L
E
N
Site 3
Y41
R
D
V
M
L
E
N
Y
R
N
L
L
S
L
D
Site 4
S46
E
N
Y
R
N
L
L
S
L
D
E
D
N
I
P
Site 5
S59
I
P
P
E
D
D
I
S
V
G
F
T
S
K
G
Site 6
T63
D
D
I
S
V
G
F
T
S
K
G
L
S
P
K
Site 7
S64
D
I
S
V
G
F
T
S
K
G
L
S
P
K
E
Site 8
S68
G
F
T
S
K
G
L
S
P
K
E
N
N
K
E
Site 9
Y78
E
N
N
K
E
E
L
Y
H
L
V
I
L
E
R
Site 10
S88
V
I
L
E
R
K
E
S
H
G
I
N
N
F
D
Site 11
Y112
K
F
D
S
L
W
D
Y
D
V
K
N
Y
K
G
Site 12
T129
L
T
C
N
K
N
L
T
H
R
K
D
Q
Q
H
Site 13
S139
K
D
Q
Q
H
N
K
S
S
I
H
F
S
L
K
Site 14
S140
D
Q
Q
H
N
K
S
S
I
H
F
S
L
K
Q
Site 15
S144
N
K
S
S
I
H
F
S
L
K
Q
S
V
S
I
Site 16
S148
I
H
F
S
L
K
Q
S
V
S
I
R
D
S
A
Site 17
S150
F
S
L
K
Q
S
V
S
I
R
D
S
A
H
Q
Site 18
S154
Q
S
V
S
I
R
D
S
A
H
Q
Y
F
I
H
Site 19
Y158
I
R
D
S
A
H
Q
Y
F
I
H
D
K
P
F
Site 20
Y178
K
L
K
N
N
I
R
Y
A
G
N
K
Y
V
K
Site 21
Y183
I
R
Y
A
G
N
K
Y
V
K
C
F
E
N
K
Site 22
S194
F
E
N
K
I
G
L
S
L
Q
A
Q
L
A
E
Site 23
T207
A
E
L
Q
R
F
Q
T
G
E
K
M
Y
E
C
Site 24
Y212
F
Q
T
G
E
K
M
Y
E
C
N
P
V
E
K
Site 25
S220
E
C
N
P
V
E
K
S
I
N
S
S
S
V
S
Site 26
S223
P
V
E
K
S
I
N
S
S
S
V
S
P
L
P
Site 27
S224
V
E
K
S
I
N
S
S
S
V
S
P
L
P
P
Site 28
S225
E
K
S
I
N
S
S
S
V
S
P
L
P
P
C
Site 29
S227
S
I
N
S
S
S
V
S
P
L
P
P
C
V
K
Site 30
Y240
V
K
N
I
C
N
K
Y
R
K
I
L
K
Y
P
Site 31
Y246
K
Y
R
K
I
L
K
Y
P
L
L
H
T
Q
Y
Site 32
T251
L
K
Y
P
L
L
H
T
Q
Y
G
R
T
H
I
Site 33
Y253
Y
P
L
L
H
T
Q
Y
G
R
T
H
I
R
E
Site 34
S273
N
D
C
G
K
A
F
S
K
S
S
N
L
T
N
Site 35
S275
C
G
K
A
F
S
K
S
S
N
L
T
N
H
Q
Site 36
T279
F
S
K
S
S
N
L
T
N
H
Q
R
I
H
S
Site 37
Y291
I
H
S
G
Q
R
P
Y
K
C
N
E
C
G
K
Site 38
T314
T
R
H
Q
R
V
H
T
G
E
K
P
Y
Q
C
Site 39
Y319
V
H
T
G
E
K
P
Y
Q
C
N
I
C
G
K
Site 40
S329
N
I
C
G
K
V
C
S
Q
N
S
N
L
A
S
Site 41
S332
G
K
V
C
S
Q
N
S
N
L
A
S
H
Q
R
Site 42
S336
S
Q
N
S
N
L
A
S
H
Q
R
M
H
T
G
Site 43
T342
A
S
H
Q
R
M
H
T
G
E
K
P
Y
K
C
Site 44
Y347
M
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 45
T370
W
G
H
E
R
I
H
T
G
E
K
P
Y
K
C
Site 46
S389
K
A
F
A
E
R
S
S
L
T
Q
H
K
R
I
Site 47
T398
T
Q
H
K
R
I
H
T
G
E
K
P
Y
I
C
Site 48
Y403
I
H
T
G
E
K
P
Y
I
C
N
E
C
G
K
Site 49
S443
C
G
R
A
F
I
Q
S
S
S
L
V
E
H
Q
Site 50
S445
R
A
F
I
Q
S
S
S
L
V
E
H
Q
R
I
Site 51
T454
V
E
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 52
T480
H
L
W
G
H
Q
R
T
H
T
G
E
K
P
Y
Site 53
T482
W
G
H
Q
R
T
H
T
G
E
K
P
Y
K
C
Site 54
Y487
T
H
T
G
E
K
P
Y
K
C
T
E
C
G
K
Site 55
T497
T
E
C
G
K
A
F
T
E
R
S
N
L
T
Q
Site 56
S500
G
K
A
F
T
E
R
S
N
L
T
Q
H
K
K
Site 57
T510
T
Q
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 58
Y565
L
G
D
H
Q
K
S
Y
N
R
E
K
H
I
K
Site 59
Y573
N
R
E
K
H
I
K
Y
N
E
T
K
I
K
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation