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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF573
Full Name:
Zinc finger protein 573
Alias:
Type:
Mass (Da):
75883
Number AA:
645
UniProt ID:
Q86YE8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
F
S
R
Q
E
W
E
Y
L
D
P
N
Q
R
D
Site 2
Y33
D
P
N
Q
R
D
L
Y
R
D
V
M
L
E
N
Site 3
Y41
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 4
S46
E
N
Y
R
N
L
V
S
L
G
G
H
S
I
S
Site 5
T75
W
M
I
L
R
E
E
T
Q
F
T
D
L
D
L
Site 6
T78
L
R
E
E
T
Q
F
T
D
L
D
L
Q
C
E
Site 7
Y95
S
Y
I
E
V
P
T
Y
E
T
D
I
S
S
T
Site 8
S100
P
T
Y
E
T
D
I
S
S
T
Q
L
Q
S
I
Site 9
S101
T
Y
E
T
D
I
S
S
T
Q
L
Q
S
I
Y
Site 10
S106
I
S
S
T
Q
L
Q
S
I
Y
K
R
E
K
L
Site 11
Y108
S
T
Q
L
Q
S
I
Y
K
R
E
K
L
Y
E
Site 12
Y114
I
Y
K
R
E
K
L
Y
E
C
K
K
C
Q
K
Site 13
S124
K
K
C
Q
K
K
F
S
S
G
Y
Q
L
I
L
Site 14
Y142
F
H
V
I
E
R
P
Y
E
C
K
E
C
G
K
Site 15
Y155
G
K
N
F
R
S
G
Y
Q
L
T
L
H
Q
R
Site 16
T158
F
R
S
G
Y
Q
L
T
L
H
Q
R
F
H
T
Site 17
T165
T
L
H
Q
R
F
H
T
G
E
K
P
Y
E
C
Site 18
Y170
F
H
T
G
E
K
P
Y
E
C
T
E
C
G
K
Site 19
Y183
G
K
N
F
R
S
G
Y
Q
L
T
V
H
Q
R
Site 20
T186
F
R
S
G
Y
Q
L
T
V
H
Q
R
F
H
T
Site 21
T193
T
V
H
Q
R
F
H
T
G
E
K
T
Y
E
C
Site 22
T197
R
F
H
T
G
E
K
T
Y
E
C
R
Q
C
G
Site 23
Y198
F
H
T
G
E
K
T
Y
E
C
R
Q
C
G
K
Site 24
T221
V
Q
H
E
R
I
H
T
G
G
K
P
Y
E
C
Site 25
Y226
I
H
T
G
G
K
P
Y
E
C
Q
E
C
G
R
Site 26
S236
Q
E
C
G
R
A
F
S
Q
G
G
H
L
R
I
Site 27
T249
R
I
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 28
Y254
V
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 29
T262
K
C
K
E
C
G
K
T
F
S
R
R
S
N
L
Site 30
S264
K
E
C
G
K
T
F
S
R
R
S
N
L
V
E
Site 31
S267
G
K
T
F
S
R
R
S
N
L
V
E
H
G
Q
Site 32
Y282
F
H
T
D
E
K
P
Y
I
C
E
K
C
G
K
Site 33
T298
F
R
R
G
H
Q
L
T
V
H
Q
R
V
H
T
Site 34
T305
T
V
H
Q
R
V
H
T
G
K
K
P
Y
E
C
Site 35
Y310
V
H
T
G
K
K
P
Y
E
C
K
E
C
G
K
Site 36
T321
E
C
G
K
G
Y
T
T
A
S
Y
F
L
L
H
Site 37
S323
G
K
G
Y
T
T
A
S
Y
F
L
L
H
Q
R
Site 38
Y324
K
G
Y
T
T
A
S
Y
F
L
L
H
Q
R
I
Site 39
Y338
I
H
K
G
G
K
P
Y
E
C
K
E
C
K
K
Site 40
T346
E
C
K
E
C
K
K
T
F
T
L
Y
R
N
L
Site 41
T348
K
E
C
K
K
T
F
T
L
Y
R
N
L
T
R
Site 42
Y350
C
K
K
T
F
T
L
Y
R
N
L
T
R
H
Q
Site 43
T374
E
C
K
Q
C
G
K
T
Y
T
T
G
S
K
L
Site 44
S379
G
K
T
Y
T
T
G
S
K
L
F
Q
H
Q
K
Site 45
T387
K
L
F
Q
H
Q
K
T
H
T
G
E
K
P
Y
Site 46
Y394
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 47
S404
K
E
C
G
K
A
F
S
L
Y
G
Y
L
K
Q
Site 48
Y406
C
G
K
A
F
S
L
Y
G
Y
L
K
Q
H
Q
Site 49
Y408
K
A
F
S
L
Y
G
Y
L
K
Q
H
Q
K
I
Site 50
S460
Q
E
C
G
K
A
Y
S
T
G
S
N
L
I
Q
Site 51
T471
N
L
I
Q
H
R
K
T
H
T
G
E
K
P
Y
Site 52
Y478
T
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 53
T486
K
C
K
E
C
G
K
T
F
S
L
H
G
Y
L
Site 54
S488
K
E
C
G
K
T
F
S
L
H
G
Y
L
N
Q
Site 55
Y492
K
T
F
S
L
H
G
Y
L
N
Q
H
Q
K
I
Site 56
Y506
I
H
T
G
M
K
P
Y
E
C
K
V
C
R
K
Site 57
T516
K
V
C
R
K
T
F
T
F
Y
R
N
L
T
L
Site 58
Y518
C
R
K
T
F
T
F
Y
R
N
L
T
L
H
Q
Site 59
T522
F
T
F
Y
R
N
L
T
L
H
Q
S
I
H
T
Site 60
T542
E
C
K
E
C
G
K
T
F
R
R
S
S
H
L
Site 61
S546
C
G
K
T
F
R
R
S
S
H
L
T
A
H
Q
Site 62
S547
G
K
T
F
R
R
S
S
H
L
T
A
H
Q
S
Site 63
T550
F
R
R
S
S
H
L
T
A
H
Q
S
I
H
A
Site 64
S554
S
H
L
T
A
H
Q
S
I
H
A
D
K
K
P
Site 65
Y562
I
H
A
D
K
K
P
Y
E
C
K
E
C
G
K
Site 66
Y574
C
G
K
A
F
K
M
Y
G
Y
L
T
Q
H
Q
Site 67
Y576
K
A
F
K
M
Y
G
Y
L
T
Q
H
Q
K
I
Site 68
Y590
I
H
T
G
G
K
P
Y
E
C
K
E
C
G
K
Site 69
S600
K
E
C
G
K
A
F
S
R
A
S
N
L
V
Q
Site 70
S603
G
K
A
F
S
R
A
S
N
L
V
Q
H
E
R
Site 71
T613
V
Q
H
E
R
I
H
T
G
E
K
P
Y
V
C
Site 72
Y618
I
H
T
G
E
K
P
Y
V
C
K
Q
C
G
K
Site 73
T626
V
C
K
Q
C
G
K
T
F
R
Y
G
S
A
L
Site 74
S631
G
K
T
F
R
Y
G
S
A
L
K
A
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation