KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NT5DC4
Full Name:
5'-nucleotidase domain-containing protein 4
Alias:
Type:
Mass (Da):
48951
Number AA:
428
UniProt ID:
Q86YG4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
F
G
F
D
M
D
Y
T
L
A
A
Y
K
S
P
Site 2
Y30
M
D
Y
T
L
A
A
Y
K
S
P
A
Y
E
A
Site 3
S32
Y
T
L
A
A
Y
K
S
P
A
Y
E
A
L
T
Site 4
Y35
A
A
Y
K
S
P
A
Y
E
A
L
T
F
E
L
Site 5
Y52
E
R
L
V
C
I
G
Y
P
H
E
I
L
R
Y
Site 6
Y59
Y
P
H
E
I
L
R
Y
T
Y
D
P
T
F
P
Site 7
T60
P
H
E
I
L
R
Y
T
Y
D
P
T
F
P
T
Site 8
Y61
H
E
I
L
R
Y
T
Y
D
P
T
F
P
T
R
Site 9
T64
L
R
Y
T
Y
D
P
T
F
P
T
R
R
L
V
Site 10
Y107
E
A
E
I
W
S
F
Y
P
S
K
F
I
Q
R
Site 11
Y148
F
F
S
G
C
S
R
Y
T
N
C
D
T
G
Y
Site 12
S163
Q
H
G
N
L
F
M
S
F
R
S
L
F
Q
D
Site 13
T187
Q
S
G
C
L
K
K
T
L
E
D
L
E
K
Y
Site 14
Y194
T
L
E
D
L
E
K
Y
V
K
K
D
P
R
L
Site 15
T218
V
G
K
V
F
L
A
T
N
S
S
Y
N
Y
T
Site 16
S220
K
V
F
L
A
T
N
S
S
Y
N
Y
T
N
A
Site 17
Y224
A
T
N
S
S
Y
N
Y
T
N
A
I
M
T
Y
Site 18
S236
M
T
Y
L
F
S
I
S
E
A
E
A
S
G
R
Site 19
S241
S
I
S
E
A
E
A
S
G
R
P
W
R
S
Y
Site 20
Y248
S
G
R
P
W
R
S
Y
F
D
L
I
V
V
D
Site 21
T273
L
V
L
R
Q
V
N
T
D
S
G
K
L
H
V
Site 22
S283
G
K
L
H
V
G
T
S
T
G
P
H
Q
H
C
Site 23
Y293
P
H
Q
H
C
A
V
Y
S
G
G
S
S
D
M
Site 24
Y314
V
R
G
M
D
I
L
Y
I
G
D
H
I
F
G
Site 25
T334
K
K
R
Q
G
W
R
T
C
L
V
V
P
E
L
Site 26
T363
E
E
L
K
R
L
D
T
H
L
A
D
I
Y
Q
Site 27
Y369
D
T
H
L
A
D
I
Y
Q
H
M
D
G
S
S
Site 28
S395
E
I
Q
M
P
H
E
S
V
V
E
Q
E
Q
A
Site 29
S408
Q
A
N
L
D
P
A
S
C
L
L
S
C
N
Q
Site 30
S412
D
P
A
S
C
L
L
S
C
N
Q
R
S
L
P
Site 31
S417
L
L
S
C
N
Q
R
S
L
P
A
K
S
C
L
Site 32
S422
Q
R
S
L
P
A
K
S
C
L
S
S
A
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation